Search results for "Movement"
showing 10 items of 2021 documents
Impact of an oral appliance on obstructive sleep apnea severity, quality of life, and biomarkers
2017
OBJECTIVE/HYPOTHESIS To investigate outcomes including efficacy, quality of life, and levels of inflammatory markers of a mandibular advancement device (MAD) for moderate-to-severe obstructive sleep apnea (OSA). STUDY DESIGN Case-control study. METHODS Patients with apnea-hypopnea index (AHI) ≥ 15/hr who only accepted MAD therapy (study group) or who refused any treatment (control group) were recruited. At baseline and at 6 months, polysomnography, Epworth Sleepiness Scale (ESS), Functional Outcomes of Sleep Questionnaire (FOSQ), C-reactive protein (CRP), interleukin 1β, interleukin 6, and tumor necrosis factor α (TNF-α) were assessed in both groups. RESULTS At baseline, the study group (n …
Is Sleep Disruption a Cause or Consequence of Alzheimer’s Disease? Reviewing Its Possible Role as a Biomarker
2020
In recent years, the idea that sleep is critical for cognitive processing has gained strength. Alzheimer’s disease (AD) is the most common form of dementia worldwide and presents a high prevalence of sleep disturbances. However, it is difficult to establish causal relations, since a vicious circle emerges between different aspects of the disease. Nowadays, we know that sleep is crucial to consolidate memory and to remove the excess of beta-amyloid and hyperphosphorilated tau accumulated in AD patients’ brains. In this review, we discuss how sleep disturbances often precede in years some pathological traits, as well as cognitive decline, in AD. We describe the relevance of sleep to memory co…
REM sleep behavior disorder and periodic leg movements in sleep in patients with amyotrophic lateral sclerosis
2013
Introduction In the last few years, it has been increasingly recognized that patients with amyotrophic lateral sclerosis (ALS) frequently suffer of sleep-related complaints, including insomnia, restless legs syndrome, and daytime sleepiness, although, in the past, many of the nocturnal symptoms have been mainly ascribed to chronic respiratory insufficiency and hypoventilation. In addition, excluding few single cases reported, polysomnographic studies did not look for abnormal motor activity during sleep that could be indicative of Rapid Eye Movements (REM) sleep behavior disorder (RBD) and REM sleep without atonia (RSWA), which are highly prevalent in other neurodegenerative disorders with …
Hábitos de sueño de la población infantil del Grau de Gandía. Un estudio descriptivo.
2012
El insomnio es es trastorno de sueño infantil más frecuente y puede aparecer en la edad lactante o en la etapa preescolar, siendo de utilidad para la detección precoz el uso de cuestionarios de sueño, como la versión española del Pediatric Sleep Questionnaire (PSQ). Nos planteamos conocer la prevalencia de los trastornos de sueño en una población de 3 a 6 años del Grau de Gandía, utilizando para ello la versión española del PSQ mediante una encuesta autocumplimentada por los padres de los alumnos de los diferentes colegios. Se ha realizado un estudio descriptivo de corte transversal, recogiéndose 144 encuestas válidas, realizándose la entrada de los datos en una base de datos EXCEL para su …
Percentile Reference Charts for Selected Sleep Parameters for 20- to 80-Year-Old Healthy Subjects from the SIESTA Database. Referenzkurven fur ausgew…
2005
One of the aims of the SIESTA project was to establish a normative database of sleep parameters for healthy and sleep-disturbed patients. Reference data for sleep parameters in non-sleep-disturbed subjects are scarce and usually refer to means and standard deviations. However, since most of the parameters do not follow a Gaussian distribution, percentiles of the distribution provide more detailed information. The present results are based on data from 198 healthy, non-sleep-disturbed subjects (104 females) in the age range of 20 to 95 years. For every subject, two consecutive nights were polysomnographically recorded in one of the eight participating clinical centres. Percentile charts were…
The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells
2013
In this study, we demonstrate that constitutive activation of Raf-1 oncogenic signaling induces stabilization and accumulation of Aurora-A mitotic kinase that ultimately drives the transition from an epithelial to a highly invasive mesenchymal phenotype in estrogen receptor α-positive (ERα(+)) breast cancer cells. The transition from an epithelial- to a mesenchymal-like phenotype was characterized by reduced expression of ERα, HER-2/Neu overexpression and loss of CD24 surface receptor (CD24(-/low)). Importantly, expression of key epithelial-to-mesenchymal transition (EMT) markers and upregulation of the stemness gene SOX2 was linked to acquisition of stem cell-like properties such as the ab…
Novel approach to study the perception of animacy in dogs.
2017
Humans tend to perceive inanimate objects as animate based on simple motion cues. So far this perceptual bias has been studied mostly in humans by utilizing two-dimensional video and interactive displays. Considering its importance for survival, the perception of animacy is probably also widespread among animals, however two-dimensional displays are not necessarily the best approach to study the phenomenon in non-human species. Here we applied a novel method to study whether dogs recognize a dependent (chasing-like) movement pattern performed by inanimate agents in live demonstration. We found that dogs showed more interest toward the agents that demonstrated the chasing-like motion, compar…
See how it feels to move: Relationships between movement characteristics and perception of emotions in dance
2020
Music makes humans move in ways found to relate to, for instance, musical characteristics, personality, or emotional content of the music. In this study, we investigated associations between embodiments of musical emotions and the perception thereof. After collecting motion capture data of dancers moving to emotionally distinct musical stimuli, silent stick-figure animations were rated by a set of observers regarding perceived discrete emotions, while 10 movement features were computationally extracted from the motion capture data. Results indicate kinematic profiles—emotion-specific sets of movement characteristics—that furthermore conform with dimensional models of valence and arousal, su…
The otherness of social work under neoliberal governance
2013
This special issue examines the topic of ‘understanding the Other’ from a very different perspective of ‘Otherness’, which advocates that the own Otherness of social work be reflected on as well. In the contexts of many current societies, social work itself increasingly appears as a strange element – an exceptional idea – as ‘the Other’. Moreover, a question raises over whether social work itself is understandable to those who are outside of it. In this paper, social work is distinguished at three institutional levels: as a science, as a profession and as an ideology or social movement. The paper aims at analysing how social work itself is put into the position of ‘the Other’ in the current…
Partecipazione 2.0: l’avatar scende in piazza (paper 6.3.2.)
2011
Al declino della partecipazione elettorale ed alla crisi delle capacità identificanti dei partiti fanno da contrappeso nuove forme di partecipazione politica. I new media in tale contesto hanno un ruolo essenziale sia per i grandi movimenti transnazionali, sia per i comitati locali single issue e per mobilitazioni spontanee caratterizzate dal passare con estrema rapidità dal mondo virtuale alle piazze. Nuove forme di democrazia integrano le democrazie rappresentative. Le tecnologie per la comunicazione e l’informazione hanno un forte impatto sulla definizione dei confini e dell’identità della comunità politica e possono contribuire a trasformare i processi decisionali pubblici, incrementand…