Search results for "Movement"
showing 10 items of 2021 documents
Use of the Transglutaminase Reaction To Study the Dissociation of Histone N-Terminal Tails from DNA in Nucleosome Core Particles
1997
We have recently shown that core histones are glutaminyl substrates for transglutaminase (TGase) and that when native nucleosome cores are incubated with monodansylcadaverine (DNC) as donor amine, this fluorescent probe is incorporated into Gln5 and Gln19 of H3 and in Gln22 of H2B [Ballestar et al. (1996) J. Biol. Chem. 271, 18817-18825]. In the present paper, we report that the cause by which Gln22 of H2B is modified in nucleosomes but not in the free histone is the interaction of the region containing that glutamine with DNA. We have used the specificity of the TGase reaction to study the changes induced by increasing ionic strength in the interaction between the histone N-terminal tails …
Damping excessive inflammation and tissue damage in Mycobacterium tuberculosis infection by Toll IL-1 receptor 8/single Ig IL-1-related receptor, a n…
2007
Abstract Toll IL-1R 8/single Ig IL-1-related receptor (TIR8/SIGIRR) is a member of the IL-1R family, expressed by epithelial tissues and immature dendritic cells, and is regarded as a negative regulator of TLR/IL-1R signaling. Tir8-deficient mice were rapidly killed by intranasal administration of low doses of Mycobacterium tuberculosis, despite controlling efficiently the number of viable bacilli in different organs. Tir8−/−-infected mice showed an increased number of neutrophils and macrophages in the lungs; however, mycobacteria-specific CD4 and CD8 T cells were similar in Tir8−/− and Tir8+/+ mice. Exaggerated mortality of Tir8−/− mice was due to massive liver necrosis and was accompanie…
Orígenes de las movilizaciones #primaveravalenciana. Un análisis de los actores sociales más influyentes en Twitter
2018
Twitter publics have become consolidated research objects. The main aim of this article is to make a contribution to this research current by analysing the social conditions that gave shape to the hashtag #primaveravalenciana. In order to do this, this study shall follow an analysis of the early tweets giving shape to this phenomenon. This approach shall stablish a participant's typology, identifying the most influent actors and pursuying a content analysis of relevant micro-messages which pushed forward the hashtag's viral expansion in the next few days. Against theories which tend to minimise the social distinction of digital actors, data analysis shows that the hashtag's origins were in …
Signals of intensification and attenuation in orchestra and choir conduction
2017
Based on a model of communication according to which not only words but also body signals constitute lexicons (Poggi, 2007), the study presented aimes at building a lexicon of conductors’ multimodal behaviours requesting intensification and attenuation of sound intensity. In a corpus of concerts and rehearsals, the conductors’ body signals requesting to play or sing forte, piano, crescendo, diminuendo were analysed through an annotation scheme describing the body signals, their meanings, and their semiotic devices: generic codified (the same as in everyday language); specific codified (shared with laypeople but with specific meanings in conduction); direct iconic, (resemblance between visua…
« Mouvement est nécessité » Pour une relation au monde du mouvement et de la musique
2021
Starting from a stationary state in order to feed a process, the idea of movement in music can affect both the sound material and the listening (the Hoerspiel...), both the view (musical theater) and the ancillary disciplines (dance or maping-video)... Based on examples taken in the 20th and 21st centuries (Debussy, Berg, Webern, Stravinsky, Stockhausen, Kagel, Ferrari, La Monte Young, Xenakis, Adams, De Chizy, De Mey, Trapani?), musicological study ultimately deduces that the metaphor of movement is for man an experience considered fundamental to his particular relationship to the world.
The Effect of Music on Movement Perception: Synchresis in Hits for HIIT
2021
Hits for HIIT consists in a research-creation project aiming to produce both musical pieces and training exercises for, on the one hand, optimizing HIIT practice and, on the other, enriching scholarly research on the relations between music and sports. These questions and their related studies have highlighted music/movement relations and the way they are perceived. In this paper we would like to outline how we attempt to build a two-way dialogue between the production of music adapted to HIIT and the design of workouts based on the music.
La rebelión de los estudiantes
2012
La rebeldía de los jóvenes en los años sesenta se desarrolló en todo el mundo, y no se circunscribe sólo a los estudiantes sino que alcanza amplios sectores de la juventud. Los jóvenes universitarios fueron, en todo caso, actores destacados de la protesta, que se manifestó en varias facetas convergentes. En el artículo se estudia, en primer lugar, los rasgos básicos de la rebelión juvenil y en segundo lugar, las líneas básicas del movimiento estudiantil en España. The rebelliousness of youth in the sixties was developed around the world, and not confined only to students but reaches large sections of youth. The university students were, in any case, outstanding actors of the protest, which …
Alix protein is substrate of Ozz-E3 ligase and modulates actin remodeling in skeletal muscle
2012
Alix/AIP1 is a multifunctional adaptor protein that participates in basic cellular processes, including membrane trafficking and actin cytoskeleton assembly, by binding selectively to a variety of partner proteins. However, the mechanisms regulating Alix turnover, subcellular distribution, and function in muscle cells are unknown. We now report that Alix is expressed in skeletal muscle throughout myogenic differentiation. In myotubes, a specific pool of Alix colocalizes with Ozz, the substrate-binding component of the muscle-specific ubiquitin ligase complex Ozz-E3. We found that interaction of the two endogenous proteins in the differentiated muscle fibers changes Alix conformation and pro…
Enzymatically modified, nonoxidized LDL induces selective adhesion and transmigration of monocytes and T-lymphocytes through human endothelial cell m…
1999
Abstract —Circulating monocytes and T lymphocytes extravasate through the endothelium at sites of developing atheromatous lesions, where they tend to accumulate and mediate the progression of the disease. We have previously demonstrated the presence of an enzymatically degraded, nonoxidized form of LDL (E-LDL) in early human fatty streaks, which possesses major biological properties of an atherogenic lipoprotein. The effects of E-LDL on human endothelial cells have now been studied with respect to adhesion and transmigration of monocytes and T lymphocytes. E-LDL induced a rapid and dose-dependent selective adhesion of monocytes and T lymphocytes to endothelial cell monolayers within 30 min…
Apigenin‐induced nitric oxide production involves calcium‐activated potassium channels and is responsible for antiangiogenic effects
2007
Summary. Background: The dietary flavonoid apigenin (Api) has been demonstrated to exert multiple beneficial effects upon the vascular endothelium. The aim of this study was to examine whether Ca2+-activated K+ channels (KCa) are involved in endothelial nitric oxide (NO) production and antiangiogenic effects.Methods: Endothelial NO generation was monitored using a cyclic guanosine monophosphate radioimmunoassay. KCa activity and changes of the intracellular Ca2+ concentration [Ca2+]i were analyzed using the fluorescent dyes bis-barbituric acid oxonol, potassium-binding benzofuran isophthalate, and fluo-3. The endothelial angiogenic parameters measured were cell proliferation, [3H]-thymidine…