Search results for "Movement"
showing 10 items of 2021 documents
Las organizaciones solidarias un análisis de su naturaleza y significado a la luz del caso valenciano
2018
Las organizaciones de voluntariado están recibiendo una creciente atención por parte de los analistas de la acción colectiva. Para unos, en su fulgurante auge reciente, se manifiesta la estrategia privatizadora del Estado de Bienestar; para otros, son expresión de un nuevo movimiento social. En este artículo los autores utilizan la amplia evidencia reunida en el caso valenciano, mediante distintas estrategias de exploración (entrevistas abiertas, encuestas, análisis de casos), para someter a examen dichas tesis. El resultado obtenido muestra más bien la heterogeneidad, disparidad y diversidad de organizaciones existentes, su reducido tamaño de recursos y su exigua articulación interna. Los …
Cyclotriveratrylene-Containing Porphyrins
2016
International audience; The C-3-symmetric cyclotriveratrylene (CTV) was covalently bonded via click chemistry to 1, 2, 3, and 6 zinc(II) porphyrin units to various host for C-60. The binding constants, Ka, were measured from the quenching of the porphyrin fluorescence by C-60. These constants vary between 400 and 4000 M-1 and are considered weak. Computer modeling demonstrated that the zinc(II) porphyrin units, [Zn], exhibit a strong tendency to occupy the CTV cavity, hence blocking the access for C-60 to land on this site. Instead, the pincer of the type [Zn]-[Zn] and in one case [Zn]-CTV, were found to be the most probable geometry to promote host-guest associations in these systems.
MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells
2014
Osteosarcoma (OS) is the most common type of bone cancer, with a peak incidence in the early childhood. Emerging evidence suggests that treatments targeting cancer stem cells (CSCs) within a tumor can halt cancer and improve patient survival. MicroRNAs (miRNAs) have been implicated in the maintenance of the CSC phenotype, thus, identification of CSC-related miRNAs would provide information for a better understanding of CSCs. Downregulation of miRNA-29 family members (miR-29a/b/c; miR‑29s) was observed in human OS, however, little is known about the functions of miR-29s in human OS CSCs. Previously, during the characterization of 3AB-OS cells, a CSC line selected from human OS MG63 cells, we…
The Status of EGFR Modulates the Effect of miRNA-200c on ZEB1 Expression and Cell Migration in Glioblastoma Cells
2020
Migration of glioblastoma cells into surrounding tissue is one of the main features that makes this tumor incurable. We evaluated whole-genome miRNA expression profiling associated with different EGFR amplification patterns in 30 cases of primary glioblastoma. From the 64 miRNAs that showed differential expression between tumors with a high level of EGFR amplification and tumors without EGFR amplification, 40% were related with cell migration, being miR-200c the most differentially expressed between these two groups. We investigated the effect of miR-200c on ZEB1 expression and cell migration in an in vitro transfection model with a miR-200c mimic, a miR-200c inhibitor and siRNA targeting E…
Spatial Memory Drives Foraging Strategies of Wolves, but in Highly Individual Ways
2022
The ability of wild animals to navigate and survive in complex and dynamic environments depends on their ability to store relevant information and place it in a spatial context. Despite the centrality of spatial memory, and given our increasing ability to observe animal movements in the wild, it is perhaps surprising how difficult it is to demonstrate spatial memory empirically. We present a cognitive analysis of movements of several wolves (Canis lupus) in Finland during a summer period of intensive hunting and den-centered pup-rearing. We tracked several wolves in the field by visiting nearly all GPS locations outside the den, allowing us to identify the species, location and timing of ne…
Effect of chelatants on gellan gel rheological properties and setting temperature for immobilization of living bifidobacteria.
1993
The effect of various concentrations of sequestrants (sodium citrate, sodium metaphosphate, and EDTA) was studied on gellan gel (1.5-2.5% (w/v)) setting temperature and rheological properties. Addition of EDTA between 0 and 0.8% (w/v) led to a progressive decrease of setting temperature. Citrate and metaphosphate decreased this parameter when added up to 0.4 or 0.6%, depending on gellan gum concentration, eventually resulting in the absence of gel formation at room temperature for the 1.5% gellan solution containing 0.4% citrate. This effect was accompanied by a significant decrease of gel strength and stiffness and might be attributed to the binding of the divalent cations required for cha…
Kościół św. Barbary w Drogosławiu jako ważny ośrodek cecylianizmu na ziemi kłodzkiej
2017
Idee reformy cecyliańskiej znalazły podatny grunt w Drogosławiu, gdzie w 1911 roku wybudowano kościół filialny ku czci św. Barbary. Dzięki działalności kantora i organisty Bruno Kiefela (1877–1955) po raz pierwszy w hrabstwie kłodzkim wprowadzono tu śpiew chorałowy z udziałem wiernych. Kiefel zasłynął też jako wirtuoz organowy i kompozytor. Na potrzeby utworzonego przez siebie w 1911 roku chóru kościelnego napisał kilkadziesiąt utworów, które cieszyły się dużą popularnością w regionie. Ważnymi wydarzeniami w dziejach miejscowości były walne zjazdy Stowarzyszenia Cecyliańskiego Hrabstwa Kłodzkiego w 1924 i 1933 roku. Ten ostatni połączono z jubileuszem 60-lecia związku. Obrzędom liturgicznym…
¿Quién decide qué y cómo? el conflicto en torno a la participación ciudadana en el contexto del desarrollo de la iniciativa urbana: Cuenca-San Antón …
2018
This article describes the main results of an ethnographic study on citizen participation carried out in the context of the development of the Urban Initiative (2007-2015): Cuenca-Barrio de San Antón. Managed by the City Council of Cuenca and financed by the European Regional Development Funds (FEDER) under the Ministry of Economy and Finance at the Government of Spain The results of the research show how in the context of the application of neoliberal policies, citizen participation becomes the trigger for new conflicts between institutions and citizens. In this sense, it is worth noting how, in practice, institutions in their capacity as experts and not willing to dis-empower themselves, …
Miasto (a)polityczne: rzecz o pragmatyczności i ideologiczności polityki lokalnej
2016
Celem niniejszego artykułu jest przede wszystkim spojrzenie na politykę lokalną z perspektywy politologicznej i zaproponowanie rozumienia przestrzeni polityki lokalnej jako pola, które wbrew dominującej narracji politycznej jest polem o charakterze ideologicznym. Artykuł został podzielony na dwie podstawowe części - w części pierwszej zajmujemy się przede wszystkim stroną teoretyczną całego zagadnienia - zostają przedstawione założenia teoretyczne polityki lokalnej, jej właściwości, a także kwestia polityczności i ideologiczności tego poziomu sceny politycznej. W drugiej naszą intencją jest bliższe przyjrzenie się aktualnej praktyce politycznej w tym ostatnim kontekście - bazując przede wsz…
Voluntary Imitation in Alzheimer’s Disease Patients
2016
International audience; Although Alzheimer's disease (AD) primarily manifests as cognitive deficits, the implicit sensorimotor processes that underlie social interactions, such as automatic imitation, seem to be preserved in mild and moderate stages of the disease, as is the ability to communicate with other persons. Nevertheless, when AD patients face more challenging tasks, which do not rely on automatic processes but on explicit voluntary mechanisms and require the patient to pay attention to external events, the cognitive deficits resulting from the disease might negatively affect patients' behavior. The aim of the present study was to investigate whether voluntary motor imitation, i.e.…