Search results for "Mphi"

showing 10 items of 626 documents

Widespread vertical transmission and associated host sex–ratio distortion within the eukaryotic phylum Microspora

2004

Vertical transmission (VT) and associated manipulation of host reproduction are widely reported among prokaryotic endosymbionts. Here, we present evidence for widespread use of VT and associated sex-ratio distortion in a eukaryotic phylum. The Microspora are an unusual and diverse group of eukaryotic parasites that infect all animal phyla. Following our initial description of a microsporidian that feminizes its crustacean host, we survey the diversity and distribution of VT within the Microspora. We find that vertically transmitted microsporidia are ubiquitous in the amphipod hosts sampled and that they are also diverse, with 11 species of microsporidia detected within 16 host species. We f…

Male0106 biological sciencesSex DifferentiationMolecular Sequence DataZoology010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyHost-Parasite Interactions03 medical and health sciencesSex FactorsSpecies SpecificityPhylogeneticsMicrosporaAnimalsParasite hostingAmphipodaSex RatioPhylogeny030304 developmental biologyGeneral Environmental Science0303 health sciencesBase SequenceModels GeneticGeneral Immunology and MicrobiologyPhylogenetic treebiologyPhylumHost (biology)Bayes TheoremSequence Analysis DNAGeneral Medicinebiology.organism_classificationTaxonMicrosporidiaMicrosporidiaFemaleGeneral Agricultural and Biological SciencesResearch ArticleProceedings of the Royal Society of London. Series B: Biological Sciences
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Identifying a key host in an acanthocephalan-amphipod system.

2015

SUMMARYTrophically transmitted parasites may use multiple intermediate hosts, some of which may be ‘key-hosts’, i.e. contributing significantly more to the completion of the parasite life cycle, while others may be ‘sink hosts’ with a poor contribution to parasite transmission. Gammarus fossarum and Gammarus roeseli are sympatric crustaceans used as intermediate hosts by the acanthocephalan Pomphorhynchus laevis. Gammarus roeseli suffers higher field prevalence and is less sensitive to parasite behavioural manipulation and to predation by definitive hosts. However, no data are available on between-host differences in susceptibility to P. laevis infection, making it difficult to untangle the…

Male0106 biological sciences[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyGenotypeprevalenceCyprinidaeBiology010603 evolutionary biology01 natural scienceshost qualityAcanthocephalaHost-Parasite InteractionsPredationFish DiseasesRandom Allocation03 medical and health sciencesRiversGammarus roeseli[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimalsParasite hostinghost specificityAmphipoda[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyParasite transmissionMulti-host parasites030304 developmental biologyInfectivity0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyEcologyinfectivitytransmissionGenetic Variationbiology.organism_classificationCrustaceanLogistic ModelsPhenotypeInfectious DiseasesSympatric speciationPredatory BehaviorFemaleAnimal Science and ZoologyParasitologyPomphorhynchus laevisHelminthiasis Animal[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Species complexes and phylogenetic lineages of Hoferellus (Myxozoa, Cnidaria) including revision of the genus: A problematic case for taxonomy

2015

Background Myxozoans are metazoan parasites whose traditional spore morphology-based taxonomy conflicts DNA based phylogenies. Freshwater species of the genus Hoferellus are parasites of the excretory system, with several members infecting food and ornamental fish species, as well as amphibians. This study aims to increase our understanding of their molecular diversity and development, aspects about which little is known, and to generate a molecular diagnostic tool to discriminate between different pathogenic and non-pathogenic Hoferellus spp. Methods SSU and ITS rDNA phylogeny, along with morphological descriptions using light and electron microscopy were used to identify and characterize …

Male0301 basic medicineSpecies complexParasitic Diseases AnimalMolecular Sequence DataCyprinidaeZoologyTeleosteiKidneyDNA RibosomalAmphibiaFish Diseases03 medical and health sciencesCyprinus carpioSensuPhylogeneticsMode of attachmentPolyphylyAnimalsITS cloningMyxozoaPhylogenyfishMyxozoaBase SequencePhylogenetic treebiologyResearchSequence Analysis DNA030108 mycology & parasitologybiology.organism_classificationType speciesInfectious DiseasesCarassiusUltrastructureTaxonomy (biology)ParasitologyAnuraParasites & Vectors
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SARS CoV2 infection _The longevity study perspectives

2021

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MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
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Limiting immunopathology: Interaction between carotenoids and enzymatic antioxidant defences.

2015

The release of reactive oxygen and nitrogen species (ROS and RNS) during the inflammatory response generates damages to host tissues, referred to as immunopathology, and is an important factor in ecological immunology. The integrated antioxidant system, comprising endogenous antioxidant enzymes (e.g. superoxide dismutase SOD, and catalase CAT) and dietary antioxidants (e.g. carotenoids), helps to cope with immune-mediated oxidative stress. Crustaceans store large amounts of dietary carotenoids for yet unclear reasons. While being immunostimulants and antioxidants, the interaction of these pigments with antioxidant enzymes remains unclear. Here, we tested the interaction between dietary supp…

MaleAntioxidantmedicine.medical_treatmentImmunologyCrustaceanImmunopathologyEcological immunologyImmuno-stimulantsmedicine.disease_causeAntioxidantsSuperoxide dismutase03 medical and health sciencesImmune systemImmunityHemolymphmedicine[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyAnimalsAmphipodaCarotenoidComputingMilieux_MISCELLANEOUS030304 developmental biologychemistry.chemical_classificationInflammation0303 health sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologybiologySuperoxide Dismutase04 agricultural and veterinary sciencesCatalaseCarotenoidsReactive Nitrogen SpeciesOxidative StressEnzymechemistryBiochemistryCatalaseDietary Supplements040102 fisheriesbiology.protein0401 agriculture forestry and fisheries[SDV.IMM]Life Sciences [q-bio]/Immunology[SDE.BE]Environmental Sciences/Biodiversity and EcologyAntioxidantReactive Oxygen SpeciesOxidative stressDevelopmental BiologyDevelopmental and comparative immunology
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Genes coding for intermediate filament proteins closely related to the hagfish "thread keratins (TK)" alpha and gamma also exist in lamprey, teleosts…

2005

The "thread keratins (TK)" alpha and gamma so far have been considered highly specialized intermediate filament (IF) proteins restricted to hagfish. From lamprey, we now have sequenced five novel IF proteins closely related to TKalpha and TKgamma, respectively. Moreover, we have detected corresponding sequences in EST and genomic databases of teleosts and amphibians. The structure of the TKalpha genes and the positions of their deduced amino acid sequences in a phylogenetic tree clearly support their classification as type II keratins. The genes encoding TKgamma show a structure typical for type III IF proteins, whereas their positions in phylogenetic trees favor a close relationship to the…

MaleBranchiostomaDNA ComplementaryLanceletXenopusMolecular Sequence DataAmphibiansIntermediate Filament Proteinsbiology.animalKeratinAnimalsProtein IsoformsElectrophoresis Gel Two-DimensionalAmino Acid SequenceIntermediate filamentGenePhylogenyZebrafishchemistry.chemical_classificationintegumentary systembiologyPhylogenetic treeSequence Homology Amino AcidEcologyLampreyGene Expression ProfilingFishesGene Expression Regulation DevelopmentalLampreysCell BiologyExonsSequence Analysis DNAbiology.organism_classificationIntronschemistryEvolutionary biologyKeratinsFemaleHagfishesHagfishExperimental cell research
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Periodontal clinical and microbiological data in desquamative gingivitis patients.

2013

Objectives: A series of patients affected by desquamative gingivitis (DG) was investigated in order to evaluate relation patterns among clinical parameters relevant to plaque induced periodontitis, periodontal microbiological data and the presence of DG lesions. Patients and methods: Eight oral lichen planus (OLP) and four mucous membrane pemphigoid (MMP) patients were examined. Periodontal measurements (performed at six sites per tooth on all teeth) included probing depth (PD), gingival recession (REC), clinical attachment loss (CAL) and full mouth plaque (FMPS) and bleeding (FMBS) scores; the presence and the exact location (site by site) of DG lesions were carefully recorded. Sub-gingiva…

MaleDesquamative gingivitiMucous membrane pemphigoidSettore MED/50 - Scienze Tecniche Mediche ApplicateDentistrySettore MED/28 - Malattie OdontostomatologicheMedicineHumansGeneral DentistryGingival recessionAgedPeriodontitisbiologybusiness.industryPeriodontal pathogensSignificant differenceAggregatibacter actinomycetemcomitansMiddle Agedmedicine.diseasebiology.organism_classificationGingivitisDesquamative gingivitisstomatognathic diseasesPeriodontal statuOral lichen planuClinical attachment lossMucous membrane pemphigoidOral lichen planusFemalemedicine.symptombusinessClinical oral investigations
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Fate of Linear and Branched Polyether-Lipids In Vivo in Comparison to Their Liposomal Formulations by 18F-Radiolabeling and Positron Emission Tomogra…

2015

In this study, linear poly(ethylene glycol) (PEG) and novel linear-hyperbranched, amphiphilic polyglycerol (hbPG) polymers with cholesterol (Ch) as a lipid anchor moiety were radiolabeled with fluorine-18 via copper-catalyzed click chemistry. In vivo investigations via positron emission tomography (PET) and ex vivo biodistribution in mice were conducted. A systematic comparison to the liposomal formulations with and without the polymers with respect to their initial pharmacokinetic properties during the first hour was carried out, revealing remarkable differences. Additionally, cholesterol was directly labeled with fluorine-18 and examined likewise. Both polymers, Ch-PEG27-CH2-triazole-TEG-…

MaleFluorine RadioisotopesBiodistributionHydrodynamic radiusPolymers and PlasticsPolymersBioengineeringBiomaterialschemistry.chemical_compoundIn vivoAmphiphilePEG ratioMaterials ChemistryAnimalsOrganic chemistryTissue DistributionMicellesLiposomeChromatographyMice Inbred C57BLCholesterolchemistryIsotope LabelingPositron-Emission TomographyLiposomeslipids (amino acids peptides and proteins)RadiopharmaceuticalsEthylene glycolEx vivoEthersBiomacromolecules
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Microsporidia parasites disrupt the responses to cadmium exposure in a gammarid.

2011

7 pages; International audience; Microsporidia parasites are commonly found in amphipods, where they are often asymptomatic, vertically-transmitted and have several effects on host sexuality and behaviour. As amphipods are often used as models in ecotoxicological studies, we investigated the effect of microsporidian infections on energy reserves and defence capacities of Gammarus roeseli under cadmium stress. Only females were infected by two microsporidia parasites: Dictyocoela roeselum or Dictyocoela muelleri. In physiological conditions, microsporidia had no major effect on energy reserves and defence capacities of G. roeseli, while under cadmium exposure, energy reserves and antioxidant…

MaleHealth Toxicology and Mutagenesis[ SDV.TOX.ECO ] Life Sciences [q-bio]/Toxicology/EcotoxicologyMicrosporidian parasites010501 environmental sciencesToxicology01 natural sciencesMalondialdehyde[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/Symbiosis0303 health sciencesCadmiumbiologyEcologyCadmium stressGeneral MedicineConfounding factorPollutionMicrosporidiaFemale[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/EcotoxicologyCadmium[ SDV.MP.PAR ] Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyAmphipodaZoologychemistry.chemical_elementHost-Parasite Interactions03 medical and health sciencesDictyocoela muelleriSpecies SpecificityGammarus roeseliparasitic diseasesEcotoxicologyAnimals[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyAmphipodaParasitesGammarus roeseli030304 developmental biology0105 earth and related environmental sciences[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyHost (biology)fungibiology.organism_classificationCADMIUM EXPOSUREchemistryMicrosporidia[SDE.BE]Environmental Sciences/Biodiversity and EcologyEnergy MetabolismBiomarkers[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisEnvironmental pollution (Barking, Essex : 1987)
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Analysis of the tegument of Zygocotyle lunata (Trematoda: Paramphistomidae) adults by scanning electron microscopy.

2012

Paramphistomiasis is a parasitic disease caused by various species of the Paramphistomidae. These species mainly affect domestic and wild ruminants; the economic impact of these diseases is often underestimated. Traditionally, the identification of paramphistomes has been difficult and has been based on morphological aspects such as the body shape, the position of the esophagus and cecae, or the tegumental papillae. Despite the many investigations regarding the tegumental papillae for other paramphistomes, very few efforts have been made using Zygocotyle lunata, partly because many authors differ with respect to the importance of papillae in the classification of paramphistomids. Herein, we…

MaleMice Inbred BALB CbiologyRosette (schizont appearance)SnailsViral tegumentAnatomyRuminantsTrematode InfectionsParamphistomatidaebiology.organism_classificationMicestomatognathic systemMicroscopy Electron ScanningHelminthsAnimalsParasitologyIntegumentParamphistomatidaeTrematodaZygocotyle lunataEcology Evolution Behavior and SystematicsThe Journal of parasitology
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