Search results for "Multicenter"

showing 10 items of 378 documents

Robot-Assisted, Laparoscopic, and Open Radical Cystectomy: Pre-Operative Data of 1400 Patients From The Italian Radical Cystectomy Registry.

2022

The Italian Radical Cystectomy Registry (RIC) is an observational prospective study aiming to understand clinical variables and patient characteristics associated with short- and long-term outcomes among bladder cancer (BC) patients undergoing radical cystectomy (RC). Moreover, it compares the effectiveness of three RC techniques - open, robotic, and laparoscopic.From 2017 to 2020, 1400 patients were enrolled at one of the 28 centers across Italy. Patient characteristics, as well as preoperative, postoperative, and follow-up (3, 6, 12, and 24 months) clinical variables and outcomes were collected.Preoperatively, it was found that patients undergoing robotic procedures were younger (p.001) a…

Cancer ResearchItaly; RIC; multicenter; radical cystectomy; urinary bladder neoplasmsItalyOncologyRICmulticenterurinary bladder neoplasmsradical cystectomySettore MED/24 - UrologiaFrontiers in oncology
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Comparison between doppler-echocardiography and uncalibrated pulse contour method for cardiac output measurement. a multicenter observational study

2016

Objectives: Echocardiography and pulse contour methods allow, respectively, noninvasive and less invasive cardiac output estimation. The aim of the present study was to compare Doppler echocardiography with the pulse contour method MostCare for cardiac output estimation in a large and nonselected critically ill population. Design: A prospective multicenter observational comparison study. Setting: The study was conducted in 15 European medicosurgical ICUs. Patients: We assessed cardiac output in 400 patients in whom an echocardiographic evaluation was performed as a routine need or for cardiocirculatory assessment. Interventions: None. Measurements and Main Results: One echocardiographic car…

Cardiac outputgenetic structuresintensive care unitsBlood PressureDoppler echocardiographyCritical Care and Intensive Care Medicinearterial waveform analysis; cardiac output; Doppler echocardiography; echocardiography; hemodynamic monitoring; pulse contour method; Critical Care and Intensive Care Medicinehemodynamic monitoring0302 clinical medicine030202 anesthesiologyechocardiographyhumansarterial waveform analysisarterial waveform analysis; cardiac output; doppler echocardiography; echocardiography; hemodynamic monitoring; pulse contour method; heart; humans; intensive care units; linear models; monitoring; physiologic; prospective studies; blood pressure; cardiac output; echocardiography; doppler; pulse; critical care and intensive care medicinemedicine.diagnostic_testPulse (signal processing)physiologicblood pressureHeartEchocardiography Dopplercardiovascular systemCardiologysymbolsLinear ModelDoppler effectHumandoppler echocardiographymedicine.medical_specialtyIntensive Care UnitLess invasiveheartpulse contour methoddoppler03 medical and health sciencesCardiac output measurementsymbols.namesakeInternal medicinemedicinePulsearterial waveform analysiMonitoring Physiologicbusiness.industrycardiac output030208 emergency & critical care medicineDoppler echocardiographyprospective studiesProspective StudiemonitoringMulticenter studycritical care and intensive care medicineObservational studylinear modelsbusinesspulse
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Children <1 year show an inferior outcome when treated according to the traditional LGG treatment strategy: A report from the german multicenter t…

2013

Background Children diagnosed with LGG at an age <1 year are reported to have an impaired prognosis in comparison to older patients. Analysis of this subgroup could reveal the necessity to develop risk-adapted treatment approaches. Procedure Children <1 year at diagnosis (n = 66, median age 7.3 months, 33 female, none NFI) from the HIT-LGG 1996 cohort were analyzed for risk factors for EFS, PFS and OS. Several children suffered from diencephalic syndrome (DS, n = 22) and primary dissemination (DLGG, n = 9), 50 had a supratentorial midline (SML) location. Extent of resection was complete/subtotal in 12, partial in 15, biopsy in 27. Tumors were pilocytic astrocytoma WHO grade I (n = 33), othe…

ChemotherapyPediatricsmedicine.medical_specialtyPilocytic astrocytomamedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentBrachytherapyHematologymedicine.diseaseCarboplatinRadiation therapychemistry.chemical_compoundOncologychemistryMulticenter trialPediatrics Perinatology and Child HealthBiopsyCohortmedicinebusinessPediatric Blood &amp; Cancer
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High-flow nasal therapy versus noninvasive ventilation in COPD patients with mild-to-moderate hypercapnic acute respiratory failure: study protocol f…

2019

Background Noninvasive ventilation (NIV) is indicated to treat respiratory acidosis due to exacerbation of chronic obstructive pulmonary disease (COPD). Recent nonrandomized studies also demonstrated some physiological effects of high-flow nasal therapy (HFNT) in COPD patients. We designed a prospective, unblinded, multicenter, randomized controlled trial to assess the noninferiority of HFNT compared to NIV with respect to the reduction of arterial partial pressure of carbon dioxide (PaCO2) in patients with hypercapnic acute respiratory failure with mild-to-moderate respiratory acidosis. Methods We will enroll adult patients with acute hypercapnic respiratory failure, as defined by arterial…

Chronic ObstructiveTime FactorsExacerbationRespiratory ratemedicine.medical_treatmentMedicine (miscellaneous)Equivalence Trials as TopicAcute respiratory failurelaw.inventionPulmonary DiseaseHypercapnia03 medical and health sciencesPulmonary Disease Chronic ObstructiveStudy Protocol0302 clinical medicineAcute respiratory failure; Carbon dioxide; Chronic obstructive pulmonary disease; Emergency department; High-flow oxygen therapy through nasal cannula; Intensive care unit; Noninvasive ventilation; Acute Disease; Equivalence Trials as Topic; Humans; Hypercapnia; Italy; Lung; Multicenter Studies as Topic; Oxygen Inhalation Therapy; Prospective Studies; Pulmonary Disease Chronic Obstructive; Respiratory Insufficiency; Time Factors; Treatment Outcome; Noninvasive VentilationRandomized controlled triallawHigh-flow oxygen therapy through nasal cannulamedicineHumansMulticenter Studies as TopicPharmacology (medical)Intensive care unit030212 general & internal medicineProspective StudiesLungTidal volumeMechanical ventilationCOPDlcsh:R5-920business.industryEmergency departmentChronic obstructive pulmonary diseaseOxygen Inhalation Therapymedicine.diseaseIntensive care unitRespiratory acidosisTreatment OutcomeItalyCarbon dioxideAnesthesiaAcute DiseasebusinessRespiratory Insufficiencylcsh:Medicine (General)Acute respiratory failure; Carbon dioxide; Chronic obstructive pulmonary disease; Emergency department; High-flow oxygen therapy through nasal cannula; Intensive care unit; Noninvasive ventilationNoninvasive ventilation030217 neurology & neurosurgeryTrials
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[Clinical audit of patients admitted to hospital in Spain due to exacerbation of COPD (AUDIPOC study): method and organisation].

2010

There is little information regarding the clinical management of hospital inpatients diagnosed with exacerbation of Chronic Obstructive Pulmonary Disease (COPD). AUDIPOC is a clinical audit dealing with the clinical management of COPD in Spain.To examine the adequacy and validity of the instruments used to measure the variables proposed by AUDIPOC Spain (Preliminary Study) and to verify the viability of AUDIPOC in a complex environment with hospitals of different sizes, resources, and organizational layout (Pilot Study).The Preliminary Study took place in 4 hospitals and studied 213 cases. The Pilot Study took place in 30 hospitals of 6 Autonomous Communities (i.e. Regions) and studied 1203…

Clinical auditMalemedicine.medical_specialtyExacerbationPulmonary diseasePilot ProjectsPulmonary Disease Chronic ObstructivePatient AdmissionCatchment Area HealthmedicineHumansMulticenter Studies as TopicProspective StudiesIntensive care medicineCOPDMedical Auditbusiness.industryHospitals PublicGeneral Medicinemedicine.diseaserespiratory tract diseasesHospitalizationCross-Sectional StudiesResearch DesignSpainFemalebusinessFollow-Up StudiesArchivos de bronconeumologia
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Mandibular incisive canal-related prevalence, morphometric parameters, and implant placement implications : a multicenter study of 847 CBCT scans

2020

Background This study evaluated the epidemiological and morphological features of the mandibular incisive canal (MIC) using cone beam computed tomography (CBCT) in a significant sample of subjects in Brazil. Material and Methods This retrospective, multicenter study assessed 847 CBCT scans performed at four oral imaging centers. The sample comprised CBCT images acquired from dentate individuals who presented at least from tooth 35 to tooth 45 in the anterior mandible region. Data regarding patient sex and age, and MIC linear measurements (length and diameter in mm), anatomical distances (to the alveolar, buccal and lingual cortexes, inferior border of the mandible, and adjacent teeth apexes…

Cone beam computed tomographyMandible03 medical and health sciences0302 clinical medicinestomatognathic systemPrevalenceHumansMedicineGeneral DentistryDental alveolusRetrospective StudiesLateral incisorOrthodonticsMandibular incisive canalbusiness.industryResearchMandibleSpiral Cone-Beam Computed Tomography030206 dentistryCone-Beam Computed Tomography:CIENCIAS MÉDICAS [UNESCO]Apex (geometry)Implant placementstomatognathic diseasesOtorhinolaryngologyMulticenter studyUNESCO::CIENCIAS MÉDICASFemaleSurgerybusinessImplantologyBrazil
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Maternal stress and coping strategies in developmental Dyslexia: An Italian multicenter study

2017

BackgroundStudies about the impact of developmental dyslexia (DD) on parenting are scarce. Our investigation aimed to assess maternal stress levels and mothers’ copying styles in a population of dyslexic children.MethodsA total of 874 children (500 boys, 374 girls; mean age 8.32 ± 2.33 years) affected by DD was included in the study. A total of 1,421 typically developing children (789 boys, 632 girls; mean age 8.25 ± 3.19 years) were recruited from local schools of participating Italian Regions (Abruzzo, Calabria, Campania, Puglia, Umbria, Sicily) and used as control-children group. All mothers (of both DD and typically developing children) filled out an evaluation for parental stress (Pare…

Coping (psychology)lcsh:RC435-571Developmental dyslexiaPopulationDysfunctional familyChildren; Coping strategies; Developmental dyslexia; Maternal emotions; Parental stress;Children; Coping strategies; Developmental dyslexia; Maternal emotions; Parental stress; Psychiatry and Mental Health03 medical and health sciencesMaternal stressCoping strategieSettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'Educazione0302 clinical medicinelcsh:PsychiatryMaternal emotionsMedicineClinical significanceParental stresseducationChildren; Coping strategies; Developmental dyslexia; Maternal emotions; Parental stressChildrenOriginal ResearchPsychiatryCoping strategieseducation.field_of_studybusiness.industry05 social sciences050301 educationSettore MED/39 - Neuropsichiatria InfantileMulticenter studyParental strePsychiatry and Mental HealthDevelopmental dyslexiaParental stressMaternal emotionbusiness0503 education030217 neurology & neurosurgeryClinical psychology
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A Prospective Noninterventional Study to Evaluate Survival and Success of Reduced Diameter Implants Made From Titanium-Zirconium Alloy

2015

Narrow diameter implants may be at increased risk of overload due to occlusal forces; therefore, implants with higher fatigue strength may be beneficial. The aim of this observational study was to evaluate survival and success of narrow diameter (Ø 3.3 mm) TiZr alloy (Roxolid, Institut Straumann AG, Basel, Switzerland) implants for 2 years in daily dental practice. This was a prospective, non-interventional, multicenter study; no specific patient inclusion or exclusion criteria were applied. Each patient received at least one TiZr implant; the treatment plan, including implant loading and final restoration, was at the investigator's discretion. The primary outcome was implant survival and s…

Dental ImplantsTitaniummedicine.medical_specialtybusiness.industryDental Implantation EndosseousCumulative survivalTitanium zirconiumSurgeryTreatment OutcomePrimary outcomeIncreased riskDental Prosthesis DesignMulticenter studyTreatment planAlloysHumansMedicineDental Restoration FailureProspective StudiesZirconiumImplant loadingImplantOral SurgerybusinessFollow-Up StudiesJournal of Oral Implantology
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Italian multicenter study on infection hazards during dental practice: Control of environmental microbial contamination in public dental surgeries

2008

Abstract Background The present study assessed microbial contamination in Italian dental surgeries. Methods An evaluation of water, air and surface microbial contamination in 102 dental units was carried out in eight Italian cities. Results The findings showed water microbial contamination in all the dental surgeries; the proportion of water samples with microbial levels above those recommended decreased during working. With regard to Legionella spp., the proportion of positive samples was 33.3%. During work activity, the index of microbial air contamination (IMA) increased. The level of microbial accumulation on examined surfaces did not change over time. Conclusion These findings confirm …

Dental practiceChange over timemedicine.medical_specialtypublic dental surgeries; microbial contaminationLegionellaMicrobial contaminationDental Equipmentdental surgeriesmicrobial contamination; dental surgeries; hazardsEnvironmental healthEpidemiologyHumansMedicineMED/42 Igiene generale e applicataBacteriabusiness.industrylcsh:Public aspects of medicineDental EquipmentPublic Health Environmental and Occupational Healthlcsh:RA1-1270Bacteria; Biofilms; Dental Equipment; Humans; Italy; Legionella; Dental Offices; Equipment Contamination; Water Microbiologypublic dental surgeriesDental OfficesItalyMulticenter studyBiofilmsDental OfficesEquipment ContaminationEquipment Contaminationmicrobial contaminationWater MicrobiologybusinesshazardsResearch ArticleBMC Public Health
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Suppressive Efficacy by a Commercially Available Blue Lens on PPR in 610 Photosensitive Epilepsy Patients

2006

Purpose Photosensitivity can represent a serious problem in epilepsy patients, also because pharmacologic treatment is often ineffective. Nonpharmacologic treatment using blue sunglasses is effective and safe in controlling photosensitivity, but large series of patients have never been studied. Methods This multicenter study was conducted in 12 epilepsy centers in northern, central, southern, and insular Italy. A commercially available lens, named Z1, obtained in a previous trial, was used to test consecutively enrolled pediatric and adult epilepsy patients with photosensitivity. Only type 4 photosensitivity (photoparoxysmal response, PPR) was considered in the study. A standardized method …

EPILEPSY-PHOTOSENSITIVE-BLUE GLASSES-NONPHARMACOLOGICAdultMalemedicine.medical_specialtyAdolescentEpilepsy ReflexPharmacological treatmentCentral nervous system diseaseEpilepsyPhotosensitive epilepsyInternal medicineFemale patientmedicineHumansPractice Patterns Physicians'ChildAgedbusiness.industryVideotape RecordingLarge seriesElectroencephalographyMiddle Agedmedicine.diseaseTREATMENT-PHOTOPAROXYSMAL RESPONSE-PPRSurgeryClinical trialTreatment OutcomeItalyNeurologyMulticenter studyChild PreschoolAnticonvulsantsFemaleNeurology (clinical)PHOTOSENSITIVEEye Protective DevicesbusinessColor PerceptionPhotic StimulationEpilepsia
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