Search results for "Multicenter"

showing 10 items of 378 documents

It is time to abandon “Expected bladder capacity.” Systematic review and new models for children's normal maximum voided volumes

2013

Background There is an agreement to use simple formulae (expected bladder capacity and other age based linear formulae) as bladder capacity benchmark. But real normal child's bladder capacity is unknown. Aims To offer a systematic review of children's normal bladder capacity, to measure children's normal maximum voided volumes (MVVs), to construct models of MVVs and to compare them with the usual formulae. Methods Computerized, manual and grey literature were reviewed until February 2013. Epidemiological, observational, transversal, multicenter study. A consecutive sample of healthy children aged 5–14 years, attending Primary Care centres with no urologic abnormality were selected. Particip…

Pediatricsmedicine.medical_specialtyMultivariate statisticsUrinary bladderbusiness.industryUrologyBladder capacityCONSECUTIVE SAMPLEmedicine.anatomical_structureMulticenter studyChartStatisticsmedicineObservational studyNeurology (clinical)AbnormalitybusinessNeurourology and Urodynamics
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Factors Associated with Nonsuppression of HIV Infection in the Spanish VACH Cohort.

2020

We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥200 copies/mL, is documented. The possible association of HIV nonsuppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. A total of 30,843 adult patients are included; 7,358 of them (23.86%) have nonsuppressed HIV. An association is found between nonsuppression of HIV and the following variables: lower body mass index, lower age o…

Pediatricsmedicine.medical_specialtybusiness.industryCoinfectionImmunologyHuman immunodeficiency virus (HIV)HIV InfectionsViral Loadmedicine.disease_causeCD4 Lymphocyte CountInfectious DiseasesCross-Sectional StudiesMulticenter studyAnti-Retroviral AgentsRisk FactorsVirologyChild PreschoolCohortMedicineHumansbusinessAIDS research and human retroviruses
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Temperamental characteristics in childhood migraine without aura: a multicenter study

2013

Maria Esposito,1 Rosa Marotta,2 Beatrice Gallai,3 Lucia Parisi,4 Giuseppina Patriciello,1 Serena Marianna Lavano,2 Giovanni Mazzotta,5 Michele Roccella,4 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Department of Psychiatry, "Magna Graecia" University of Catanzaro, Catanzaro, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 4Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, …

Persistence (psychology)medicine.medical_specialtyNeuropsychiatric Disease and TreatmentAuramedia_common.quotation_subjectNeurosciences. Biological psychiatry. NeuropsychiatrychildrenMedicinejTCIPsychiatryRC346-429Biological Psychiatrymedia_commonOriginal ResearchChildhood migrainebusiness.industrytemperamentmedicine.diseasePsychiatry and Mental healthMulticenter studyMigrainemigraine without auraHarm avoidanceTemperament and Character InventoryTemperamentNeurology. Diseases of the nervous systembusinessClinical psychologyRC321-571
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Intramuscular tramadol versus ketorolac in patients with orthopedic and traumatologic postoperative pain: a comparative multicenter trial

1998

This 3-day, multicenter, open-label, randomized, controlled trial was undertaken to assess the postoperative analgesic effect and therapeutic safety of intramuscular tramadol compared with intramuscular ketorolac in 48 patients undergoing orthopedic surgery and having postoperative pain assessed as 75 mm or more on a 100-mm visual analogue scale. Tramadol (100 mg/2 mL ampules) was administered as needed to a maximum of 400 mg/d, and ketorolac (30 mg/1 mL ampules) was given as needed up to 90 mg/d. Nine patients who received tramadol and six who received ketorolac needed only one dose of medication to achieve satisfactory analgesia. Tramadol had a more pronounced analgesic effect than did ke…

Pharmacologymedicine.medical_specialtyChemotherapyVisual analogue scalebusiness.industrymedicine.medical_treatmentAnalgesiclaw.inventionSurgerybody regionsKetorolacRandomized controlled triallawAnesthesiaMulticenter trialOrthopedic surgerymedicinePharmacology (medical)Tramadolbusinessmedicine.drugCurrent Therapeutic Research
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Next generation diagnostic algorithm in non-small cell lung cancer predictive molecular pathology: The KWAY Italian multicenter cost evaluation study

2022

Abstract Aims The KWAY project aims to investigate the economic sustainability of the up-front NGS technologies adoption in the analysis of clinically relevant molecular alterations in NSCLC patients. Methods The diagnostic workflow and the related sustained costs of five Italian referral centers were assessed in four different evolving scenarios were analyzed. For each scenario, two alternative testing strategies were evaluated: the Maximized Standard strategy and the Maximized NGS strategy. Results For each center, the robustness of obtained results was verified through a deterministic sensitivity analysis, observing the variation of total costs based on a variation of ±20 % of the input …

Predictive molecular pathologyLung NeoplasmsTotal costCostCost; NGS; NSCLC; Predictive molecular pathology; Single-gene test; Algorithms; High-Throughput Nucleotide Sequencing; Humans; Italy; Multicenter Studies as Topic; Carcinoma Non-Small-Cell Lung; Lung NeoplasmsNSCLCRobustness (computer science)Carcinoma Non-Small-Cell LungCost evaluationMedicineHumansMulticenter Studies as TopicNon-Small-Cell LungMolecular pathologybusiness.industryCarcinomaHigh-Throughput Nucleotide SequencingHematologyReliability engineeringWorkflowOncologyEconomic sustainabilityItalyNGSSingle-gene testNon small cellbusinessAlgorithms
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The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligen…

2011

Contains fulltext : 97437.pdf (Publisher’s version ) (Open Access) BACKGROUND: The International Multi-centre ADHD Genetics (IMAGE) project with 11 participating centres from 7 European countries and Israel has collected a large behavioural and genetic database for present and future research. Behavioural data were collected from 1068 probands with ADHD and 1446 unselected siblings. The aim was to describe and analyse questionnaire data and IQ measures from all probands and siblings. In particular, to investigate the influence of age, gender, family status (proband vs. sibling), informant, and centres on sample homogeneity in psychopathological measures. METHODS: Conners' Questionnaires, St…

ProbandResearch designMale110 012 Social cognition of verbal communicationIntelligencePerception and Actions Mental Health [DCN 1]MedizinSocial Sciencescentre effectsDevelopmental psychology2738 Psychiatry and Mental Health0302 clinical medicinelcsh:PsychiatryMulticenter Studies as Topicsibling designChildATTENTION-DEFICIT/HYPERACTIVITY DISORDERMental DisordersWechsler ScalesWechsler Adult Intelligence Scale10058 Department of Child and Adolescent PsychiatryDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental healthPhenotypeConduct disorderResearch DesignRELIABILITYFemaleFamily RelationsPsychologyClinical psychologyPsychopathologyResearch ArticleAdultlcsh:RC435-571DEFICIT HYPERACTIVITY DISORDERTWIN610610 Medicine & health150 000 MR Techniques in Brain Function03 medical and health sciencesmulti-centre studyADHD multi-centre studymedicineCriterion validityAttention deficit hyperactivity disorderHumansADHDGenetic Predisposition to Diseaseddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersSiblingMETAANALYSISFamily HealthPsychiatric Status Rating ScalesCHILD PSYCHIATRIC-PATIENTSSiblingsPARENTmedicine.disease030227 psychiatryAttention Deficit Disorder with HyperactivityCONDUCT DISORDERCRITERION VALIDITY030217 neurology & neurosurgery
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P2‐401: Reliability of DTI: A european multicenter study

2010

Psychiatry and Mental healthCellular and Molecular NeuroscienceDevelopmental NeuroscienceMulticenter studyEpidemiologyComputer scienceHealth PolicyNeurology (clinical)Geriatrics and GerontologyReliability (statistics)Reliability engineeringAlzheimer's & Dementia
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Perioperative hyperoxia: Myths and realities

2017

Pulmonary Atelectasismedicine.medical_specialtyPartial PressureAcute Lung InjuryMEDLINEHyperoxiaPerioperative Care03 medical and health sciencesPostoperative Complications0302 clinical medicineMeta-Analysis as Topic030202 anesthesiologymedicineHumansMulticenter Studies as TopicSurgical Wound InfectionHypoxiaIntraoperative ComplicationsIntensive care medicineMeta-Analysis as TopicHyperoxiaClinical Trials as TopicDose-Response Relationship Drugbusiness.industryOxygen Inhalation TherapyGeneral MedicineMythologyPerioperativeOxygenPulmonary AlveoliVasoconstrictionPractice Guidelines as Topicmedicine.symptombusiness030217 neurology & neurosurgeryRevista Española de Anestesiología y Reanimación (English Edition)
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GOLD 2017 on the way to a phenotypic approach? Analysis from the Phenotypes of COPD in Central and Eastern Europe (POPE) Cohort.

2017

The distribution of patients based on exacerbations solely is the most profound consequence of the 2017 GOLD Report http://ow.ly/4UJa309fLbM

Pulmonary and Respiratory MedicineCOPDPathologymedicine.medical_specialtybusiness.industryPulmonary diseasemedicine.diseasePhenotype03 medical and health sciencesPulmonary Disease Chronic Obstructive0302 clinical medicineCross-Sectional StudiesPhenotype030228 respiratory systemMulticenter studyCohortMedicineHumans030212 general & internal medicineEurope EasternbusinessDemographyThe European respiratory journal
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The International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three: A global synthesis

2013

This ISAAC Phase Three synthesis provides summarised information on the main findings of the study, regional tables and figures related to the prevalence and severity of current symptoms of asthma, rhinoconjunctivitis and eczema in the main regions of the world. The large number of surveyed children (≈1,200,000), the large number of centres (233) and countries (98) that participated in ISAAC Phase Three makes this study the most comprehensive survey of these diseases ever undertaken. Globally, the prevalence for current asthma, rhinoconjunctivitis and eczema in the 13-14-year age group was 14.1%, 14.6% and 7.3%, respectively. In the 6-7-year age group the prevalence for current asthma, rhin…

Pulmonary and Respiratory MedicineMalePediatricsmedicine.medical_specialtyAllergyAdolescentInternational CooperationImmunologyEczemaISAACSocioeconomic FactorSurveys and QuestionnairesEpidemiologymedicinePrevalenceHumansImmunology and AllergyPractice Patterns Physicians'ChildSocioeconomic statusChildrenRhinitiAsthmaAsthma; Children; Eczema; ISAAC; Rhinitis; Adolescent; Asthma; Child; Disease Progression; Female; Humans; International Cooperation; Male; Physician's Practice Patterns; Prevalence; Questionnaires; Socioeconomic Factors; Immunology and Allergybusiness.industryQuestionnaireDisease progressionGeneral Medicinemedicine.diseaseAsthmaSocioeconomic FactorsMulticenter studyEtiologyDisease ProgressionLocal environmentFemalePhysician's Practice PatternbusinessDemographyHuman
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