Search results for "Multidisciplinary"

showing 10 items of 4640 documents

Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Di…

2015

Purpose This study aimed to investigate the mid- to long-term outcomes of cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) for the treatment of 1-level or 2-level symptomatic cervical disc disease. Methods Medline, Embase, and the Cochrane Central Register of Controlled Trials databases were searched to identify relevant randomized controlled trials that reported mid- to long-term outcomes (at least 48 months) of CDA versus ACDF. All data were analyzed by Review Manager 5.3 software. The relative risk (RR) and 95% confidence intervals (CIs) were calculated for dichotomous variables. The weighted mean difference (WMD) and 95%CIs were calculated for conti…

medicine.medical_treatmentlcsh:MedicineAnterior cervical discectomy and fusionIntervertebral Disc Degenerationlaw.inventionDatabase and Informatics MethodsMathematical and Statistical Techniques0302 clinical medicineRandomized controlled triallawMedicine and Health SciencesDatabase Searchinglcsh:ScienceRandomized Controlled Trials as Topic030222 orthopedicsMultidisciplinaryResearch AssessmentTreatment Outcomemedicine.anatomical_structureResearch DesignMeta-analysisPhysical SciencesCervical VertebraeIntervertebral Disc DisplacementStatistics (Mathematics)DiskectomyResearch ArticleCervical vertebraemedicine.medical_specialtyDrug Research and DevelopmentSystematic ReviewsClinical Research DesignVisual analogue scaleSurgical and Invasive Medical ProceduresResearch and Analysis MethodsArthroplasty03 medical and health sciencesMusculoskeletal System ProceduresDiscectomyConfidence IntervalsmedicineHumansClinical TrialsStatistical MethodsPharmacologybusiness.industrylcsh:RArthroplastyRandomized Controlled TrialsSurgeryRelative risklcsh:QAdverse EventsClinical MedicinebusinessMathematics030217 neurology & neurosurgeryMeta-AnalysisPLoS ONE
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Ments alterades en el segle XIX: Els relats d'Edgar Allan Poe i Guy de Moupassant

2014

En el present article s’aborda la confl uencia entre l’autor nord-america Edgar Allan Poe (1809-1849) i l’autor frances Guy de Maupassant (1850-1893), que, a pesar d’estar adscrits a tendencies literaries divergents (romanticisme enfront de realisme/naturalisme), van compartir interessos tematics i formals inequivocs en l’ambit del relat. Partint de les primerenques infl uencies de la contistica de Poe sobre l’escriptura de Maupassant, aquest treball se centra en una seleccio dels relats de l’autor frances que el vinculen literariament a Poe (tant en el terreny tematic com en el narratologic), relacionats amb la fascinacio d’ambdos autors per estats mentals atipics i narradors alterats o «a…

mental disorderEdgar Allan Poerelatfrenologiacompared literature; nineteenth century literaturefrenologíarelatoGuy de MaupassantHistory and Philosophy of SciencestorytellersEdgar Allan Poe; Guy de Maupassant; relato; estados mentales; narradores; frenologíaLiteratura del segle XIX; Literatura comparadaestados mentalesnineteenth century literatureMultidisciplinaryphrenologyEdgar Allan Poe; Guy de Maupassant; story; mental disorder; storytellers; phrenologyestats mentalsLiteratura comparadaLiteratura del siglo XIXnarradoresEdgar Allan Poe; Guy de Maupassant; relat; estats mentals; narradors; frenologianarradorscompared literaturestoryLiteratura del segle XIXLiteratura del siglo XIX; Literatura comparadaMètode Revista de difusió de la investigació
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Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex.

2012

Expansion of CAG repeats is a common feature of various neurodegenerative disorders, including Huntington's disease. Here we show that expanded CAG repeats bind to a translation regulatory protein complex containing MID1, protein phosphatase 2A and 40S ribosomal S6 kinase. Binding of the MID1-protein phosphatase 2A protein complex increases with CAG repeat size and stimulates translation of the CAG repeat expansion containing messenger RNA in a MID1-, protein phosphatase 2A- and mammalian target of rapamycin-dependent manner. Our data indicate that pathological CAG repeat expansions upregulate protein translation leading to an overproduction of aberrant protein and suggest that the MID1-com…

metabolism [Microtubule Proteins]General Physics and AstronomyHTT protein humanRibosomal s6 kinaseMice0302 clinical medicinemetabolism [Transcription Factors]Protein Phosphatase 2Luciferasesgenetics [Nerve Tissue Proteins]genetics [Protein Biosynthesis]0303 health sciencesHuntingtin ProteinMultidisciplinarybiologyTOR Serine-Threonine KinasesNuclear ProteinsTranslation (biology)3. Good healthmetabolism [Luciferases]Microtubule Proteinsddc:500metabolism [Nuclear Proteins]genetics [Trinucleotide Repeat Expansion]Protein Bindingcongenital hereditary and neonatal diseases and abnormalitiesMTOR protein humanUbiquitin-Protein LigasesBlotting WesternNerve Tissue Proteinsmetabolism [TOR Serine-Threonine Kinases]metabolism [RNA Messenger]General Biochemistry Genetics and Molecular Biology03 medical and health sciencesgenetics [RNA Messenger]mental disordersHuntingtin ProteinAnimalsHumansEukaryotic Small Ribosomal SubunitRNA MessengerNucleotide Motifs030304 developmental biologyMessenger RNAmetabolism [Nerve Tissue Proteins]RNAmetabolism [Protein Phosphatase 2]General ChemistryProtein phosphatase 2Molecular biologynervous system diseasesProtein Biosynthesisbiology.proteinTrinucleotide repeat expansionTrinucleotide Repeat Expansion030217 neurology & neurosurgeryMid1 protein humanHeLa CellsTranscription FactorsNature communications
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L’impacte social de la mobilitat humana. Una visió no dicotòmica del canvi cultural i individual

2014

Aquest article reflexiona sobre el balanc de costos/beneficis en les societats, tant emissores de poblacio com receptores, i en les persones que les componen. Es treballa en tot moment des de la doble perspectiva grupal/individual. Es descriu el proces dinamic de canvi i l’impacte del canvi cultural i individual produit per l’aculturacio. Tot aco esguitat per algunes reflexions sorgides d’una societat nomada com la nostra.

migracionsMultidisciplinaryimpacto socialmigracionesimpacte psicològicmigrationimpacto psicológicopsicosociologíaHistory and Philosophy of Sciencecambiopsychosociologypersonalitymigration; personality; change; social impact; psychological impactcanviimpacte socialpersonalitatmigracions; personalitat; canvi; impacte social; impacte psicològicchangesocial impactpersonalidadmigraciones; personalidad; cambio; impacto social; impacto psicológicopsychological impactpsicosociologia
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Sediment quality of the ecoregion Engure, Gulf of Riga, assessed by using ecotoxicity tests and biomarker responses

2014

Pētījuma mērķis bija novērtēt Engures ekoreģiona (Rīgas līča rietumu piekrastes) sedimentu kvalitāti, izmantojot sedimentu ekotoksicitātes testus. Lai noteiktu bioloģiskās atbildes reakcijas uz dažāda veida stresoriem, kā testorganismi pielietotas sānpeldes Monoporeia affinis and Pontogammarus robustoides, un izvēlēti biomarķieri (AChE, GST, GR, CAT, MT), kas noteikti gliemenēs Macoma balthica. Engures ekoreģionu varētu uzskatīt par nepiesārņotu rajonu, jo tā sedimentus raksturo salīdzinoši zemas smago metālu koncentrācijas. Engures ekoreģiona sedimentu ekotoksicitātes testu rezultāti neuzrādīja statistiski būtisku (>20% mirstība) toksisko efektu. Testorganismu izdzīvotība bija robežās no 8…

molluscsecotoxicity testsgeographyMultidisciplinarygeography.geographical_feature_categoryEcologyScienceGulf of RigaamphipodsQbiomarkersSedimentSink (geography):NATURAL SCIENCES::Biology [Research Subject Categories]NutrientEcoregionEnvironmental scienceMarine ecosystemEcosystemgulf of rigaEcotoxicityOrganismProceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.
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A Pilot Study on Developing Newsgames in Collaboration between Journalism and Computer Science Students

2019

Abstract Producing digital and interactive journalistic products offers unique and important new learning opportunities for journalism education. This study analysed the experiences of two pilot courses on so-called ‘newsgames’ in a Finnish university in 2015 and 2017. The data consisted of the newsgames and other materials produced by the students, student feedback concerning the course and observations of teachers throughout the project. Our analysis demonstrates how producing newsgames in the context of higher education may foster project-based learning experiences, something that has been relatively rare in traditional journalism education. Collaboration with media companies also offere…

monitieteisyysHigher educationbusiness.industryjournalism practiceCommunication05 social sciencespelisuunnitteluprojektioppiminen050301 educationnewsgames050801 communication & media studiesContext (language use)journalism education0508 media and communicationsLearning opportunitieshyötypelitproject-based learningPedagogyComputingMilieux_COMPUTERSANDEDUCATIONJournalismjournalistiikkabusiness0503 educationmultidisciplinarydigitaaliset pelit
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Elucidating geological and biological processes underlying the diversification of Sulawesi tarsiers.

2009

Because of their exceptionally long independent evolution, a range diminution of their Eocene relatives, and a remarkable subsequent diversification in Southeast Asia, tarsiers are of particular importance to evolutionary primatologists. Little is known, however, on the processes shaping the radiation of these small enigmatic primates—especially on the Indonesian island of Sulawesi, their center of endemism. Geological reconstructions and progress in applying DNA sequence information to divergence dating now provide us with the tools and background to comprehend tarsier dispersal. Here, we describe effects of plate-tectonic movements, Pleistocene sea level changes, and hybridization on the…

mtDNA control regionMost recent common ancestorGeological PhenomenaMultidisciplinaryBase SequenceRange (biology)EcologyBiogeographyMolecular Sequence DataPopulation DynamicsTarsiidaeGenetic VariationBiologyBiological Sciencesbiology.organism_classificationTarsierMitochondriaEvolution MolecularPhylogeographyIndonesiaBiological dispersalAnimalsEndemismPhylogenyBiological PhenomenaProceedings of the National Academy of Sciences of the United States of America
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Engraved in the Body : Ways of Reading Finnish People's Memories of Mental Hospitals

2021

Finnish psychiatric practice has been heavily based on institutionalization. Mental hospitalsMental hospital have thus been part of Finns' lives in many ways. Our multidisciplinary researchMultidisciplinary research group has investigated how experiences in these institutions are remembered today by analysing writings by patients, relatives, personnel and their children, collected in 2014--2015 with the Finnish Literature Society. The memoriesMemory cover phases of psychiatric care from the 1930s to the mid-2010s. This article presents multiple ways in which experiences that are often difficult verbalize can be interpreted, e.g. by drawing on perspectives from creative, artistic and cultura…

muistottaiteellinen tutkimusartistic researchemotionmental hospitalpsykiatriset potilaattaidecorporealityruumiillisuusmental illnessmemoryfigurative languagemielisairaalatpsykiatriset sairaalataffectpsykiatrinen hoitotunteethistory of psychiatrymuistaminenmultidisciplinary researchFinlandarchivestraumatmuisti (kognitio)
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La importància del coneixement de les eixides professionals en Relacions Laborals

2010

L’objectiu és presentar un projecte la finalitat del qual ha estat mostrar als estudiants de primer de Relacions Laborals quines són les principals eixides professionals, les competències i habilitats requerides per les esmentades eixides i la seua vinculació amb les matèries objecte d’estudi de la titulació. El projecte està especialment dirigit al grup d'estudiants que ha seguit el Projecte d'Innovació Educativa (PIE) durant el període 2005-2009. Per això s’ha comptat amb la participació en aquest projecte del professorat que havia impartit docència al PIE i també amb un grup de professionals externs a la universitat, directament vinculats amb aquestos estudis. Aquestos professionals van …

multidisciplinariedadindustrial relations skills qualifications career multidisciplinary complementarysalidas profesionalescompetencias; cualificaciones; salidas profesionales; multidisciplinariedadcualificacionescompetenciaslcsh:Llcsh:L7-991lcsh:Education (General)lcsh:Education@tic: Revista d'Innovació Educativa
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Interaction and eEducation: What kind of support is needed to develop university teaching?

2014

Higher education institutions are facing an on-going pressure to develop pedagogy which promotes high-quality learning, supports studying in various learning circumstances, and integrates technology. Flexible and meaningful learning possibilities which develop skills for the world of work, like active agency, collaboration and construction of knowledge through interaction with others, are needed in university education. To address these needs, a multidisciplinary network for developing university teaching was introduced at the University of Jyväskylä, Finland in 2011. Even though the main focus of the developmental work is based on the strategy of the university jointly shared among teacher…

multidisciplinary networkteaching developmenthigher educationComputingMilieux_COMPUTERSANDEDUCATIONinteraktiivisuuseEducation
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