Search results for "Multifocality"

showing 3 items of 3 documents

Identification of clinical phenotypes and related survival in patients with large hccs

2021

Background. Hepatocellular carcinoma (HCC) factors, especially maximum tumor diameter (MTD), tumor multifocality, portal vein thrombosis (PVT), and serum alpha-fetoprotein (AFP), influence survival. Aim. To examine patterns of tumor factors in large HCC patients. Methods. A database of large HCC patients was examined. Results. A multiple Cox proportional hazard model on death identified low serum albumin levels and the presence of PVT and multifocality, with each having a hazard ratio ≥2.0. All combinations of these three parameters were examined in relation to survival. Using univariate Cox analysis, the combination of albumin &gt

0301 basic medicineCancer Researchmedicine.medical_specialtyPVTSettore MED/12 - GASTROENTEROLOGIASerum albuminlcsh:RC254-282GastroenterologyArticle03 medical and health sciences0302 clinical medicineInternal medicineMedicinePlateletHCCneoplasmsSurvival ratePVT.biologybusiness.industryProportional hazards modelAlbuminHazard ratioSettore MED/09 - MEDICINA INTERNAAlbuminMultifocalityHCC; large; phenotypes; PVT; multifocality; albuminlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseasedigestive system diseasesPortal vein thrombosisAlbumin; HCC; Large; Multifocality; Phenotypes; PVTPhenotypesPhenotype030104 developmental biologyOncology030220 oncology & carcinogenesisHepatocellular carcinomabiology.proteinLargebusiness
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Synchronous parenchymal renal tumors of different histology in the same kidney

2009

Background: Synchronous primary cortical tumors of different histology in the same kidney are rare. Preoperative awareness of this coexistence is important, since it can help in planning the surgical approach. Purpose: To describe the imaging findings observed in five patients with two parenchymal malignant tumors of different histology in the same kidney. Material and Methods: We reviewed the pathology reports of 381 patients operated for renal tumors from January 2000 to March 2007. The medical records of all patients with multiple, synchronous, primary lesions of different histology in the same kidney were reviewed with special attention to imaging findings and indications on the nature…

AdultMalemedicine.medical_specialtyPathologyContrast MediaRenal tumorImagingDifferent subtypeNeoplasms Multiple PrimaryRetrospective StudieParenchymaCarcinomamedicineHumansRadiology Nuclear Medicine and imagingCarcinoma Renal CellRetrospective StudiesAgedAged 80 and overKidneyRadiological and Ultrasound Technologybusiness.industryMedical recordMultifocalityKidney NeoplasmHistologyRetrospective cohort studyGeneral MedicineMiddle Agedmedicine.diseaseKidney NeoplasmsCarcinoma Papillarymedicine.anatomical_structureAdenocarcinomaFemaleRadiologybusinessTomography X-Ray ComputedKidney diseaseAdenocarcinoma Clear CellHuman
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Prognostic role of tumour multifocality in renal cell carcinoma.

2012

Study Type - Therapy (multi-centre cohort) Level of Evidence3b What's known on the subject? and What does the study add? In RCC about 5% of the patients presented multifocal disease. Prevalence of tumour multifocality was associated with a higher percentage of symptomatic RCC, higher pathological TNM stages, higher tumour grade and higher prevalence of tumour necrosis. Although in univariable analysis multifocal tumours had lower probability of CSS, tumour multifocality did not retain an independent predictive role in multivariable analysis. Patient age at surgery, gender, mode of presentation, pathological N stage and presence of metastases were independent predictors of CSS in multivariab…

Cancer-specific survivalMalePrognosiUrologyRenal cell carcinoma; oncology; PrognosisNephrectomyFollow-Up StudieRetrospective StudiePrevalenceHumansCarcinoma Renal CellNeoplasm StagingProportional Hazards ModelsRetrospective StudiesPrognostic factorCancer-specific survival; Multifocality; Prognostic factor; Renal cell carcinomaKidney NeoplasmMultifocalityMiddle AgedPrognosisRenal cell carcinomaKidney NeoplasmsSurvival RateItalyoncologyProportional Hazards ModelFemaleTomography X-Ray ComputedHumanFollow-Up Studies
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