Search results for "Multiple"
showing 10 items of 2678 documents
Blind source separation for OFDM with filtering colored noise out
2011
Two blind algorithms that are developed with the intention of improving the symbol detection of Orthogonal Frequency Division Multiplexing (OFDM) techniques are proposed in this paper. OFDM systems are easy to equalize in implementations. The schemes are based on the theories of blind source separation (BSS). They are among the premier mechanisms used for extracting unobserved signals from observed mixtures in signal processing. In this study noise component of the received signal mixture is tried to be filtered out. A scalar energy function with the iterative fixed point rule for receive signal is used in determining the filter coefficients while taking the time correlation properties of t…
Anamorphic fractional Fourier transform: optical implementation and applications
1995
An additional degree of freedom is introduced to fractional-Fourier-transform systems by use of anamorphic optics. A different fractional Fourier order along the orthogonal principal directions is performed. A laboratory experimental system shows preliminary results that demonstrate the proposed theory. Applications such as anamorphic fractional correlation and multiplexing in fractional domains are briefly suggested.
Differentiating Multiple Sclerosis From AQP4-Neuromyelitis Optica Spectrum Disorder and MOG-Antibody Disease With Imaging.
2023
Background and ObjectivesRelapsing-remitting multiple sclerosis (RRMS), aquaporin-4 antibody–positive neuromyelitis optica spectrum disorder (AQP4-NMOSD), and myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) may have overlapping clinical features. There is an unmet need for imaging markers that differentiate between them when serologic testing is unavailable or ambiguous. We assessed whether imaging characteristics typical of MS discriminate RRMS from AQP4-NMOSD and MOGAD, alone and in combination.MethodsAdult, nonacute patients with RRMS, APQ4-NMOSD, and MOGAD and healthy controls were prospectively recruited at the National Hospital for Neurology and Neurosurgery (L…
An attention-based weakly supervised framework for spitzoid melanocytic lesion diagnosis in whole slide images
2021
[EN] Melanoma is an aggressive neoplasm responsible for the majority of deaths from skin cancer. Specifically, spitzoid melanocytic tumors are one of the most challenging melanocytic lesions due to their ambiguous morphological features. The gold standard for its diagnosis and prognosis is the analysis of skin biopsies. In this process, dermatopathologists visualize skin histology slides under a microscope, in a highly time-consuming and subjective task. In the last years, computer-aided diagnosis (CAD) systems have emerged as a promising tool that could support pathologists in daily clinical practice. Nevertheless, no automatic CAD systems have yet been proposed for the analysis of spitzoi…
Algorithms for Graph and Network Analysis: Graph Alignment
2019
In this article we discuss the problem of graph alignment, which has been longly referred to for the purpose of analyzing and comparing biological networks. In particular, we describe different facets of graph alignment, according to the number of input networks, the fixed output objective, the possible heterogeneity of input data. Accordingly, we will discuss pairwise and multiple alignment, global and local alignment, etc. Moreover, we provide a comprehensive overview of the algorithms and techniques proposed in the literature to solve each of the specific considered types of graph alignment. In order to make the material presented here complete and useful to guide the reader in the use o…
Monoclonal gammopathy of ocular significance (MGOS) – a short survey of corneal manifestations and treatment outcomes
2021
Monoclonal gammopathy of ocular significance (MGOS) is a rare subset of monoclonal gammopathy of clinical significance occurring secondary to plasma cell disorders and causing ocular manifestations. We identified 23 patients with paraproteinemic keratopathy (PPK) in the setting of monoclonal gammopathy of unknown significance (MGUS, 10), smoldering multiple myeloma (SMM, 3) or multiple myeloma (MM, 10). Many of these patients with PPK (11/23) presented decreased vision. All patients with MM and 40% of those with other diagnoses such as SMM and MGUS received systemic therapy with or without autologous stem cell transplantation. Four eyes of four patients were treated by penetrating keratopla…
Circulating tumor and immune cells for minimally invasive risk stratification of smoldering multiple myeloma
2022
Abstract Purpose: Early intervention in smoldering multiple myeloma (SMM) requires optimal risk stratification to avoid under- and overtreatment. We hypothesized that replacing bone marrow (BM) plasma cells (PC) for circulating tumor cells (CTC), and adding immune biomarkers in peripheral blood (PB) for the identification of patients at risk of progression due to lost immune surveillance, could improve the International Myeloma Working Group 20/2/20 model. Experimental Design: We report the outcomes of 150 patients with SMM enrolled in the iMMunocell study, in which serial assessment of tumor and immune cells in PB was performed every 6 months for a period of 3 years since enrollment. Resul…
FlowCT for the analysis of large immunophenotypic data sets and biomarker discovery in cancer immunology
2022
Key Points FlowCT is a new computational workspace for unveiling cellular diversity and objectively identifying biomarkers in large immune monitoring studies.FlowCT identified T-cell biomarkers predictive of malignant transformation and survival in SMM and active MM data sets.
Food insecurity with hunger and sexual behavior among adolescents from 53 countries
2021
Objectives: To examine the relationship of food insecurity with sexual intercourse, multiple sexual partners and non-condom use. Methods: Data on food insecurity (hunger) and sexual behaviors from 205,296 adolescents from 53 countries. Associations were analyzed using meta-analysis. Results: Overall, 16.0% of the adolescents ever had sexual intercourse and the prevalence of moderate and severe food insecurity was 44.9% and 6.2%, respectively. Moderate and severe food insecurity was associated with higher odds for sexual intercourse. Any food insecurity was significantly associated with condom nonuse at last sex. Conclusions: Food insecurity was associated with higher odds of ever having sex…
Socio-Demographic Vulnerability: The Condition of Italian Young People
2009
For a kind of inertia effect, today the Italian welfare state protects the older too much and, on the contrary, it does not counter sufficiently the new risks associated with other phases of life. Not much seems to be implemented in favour of Italian young people who, as a matter of fact, seem to suffer a lot from the present changes: young people remain longer in the parental home and postpone setting up their own independent life to a most advanced age. In order to understand the situation of vulnerability increasingly widespread among young people, it seemed more and more necessary an in-depth analysis of the reasons and the subjective status of the discomfort that affects young people b…