Search results for "Muri"

Putative role of cationic amino acid transporter‐3 in murine liver metabolism

2015

Three-dimensional image analytical detection of intussusceptive pillars in murine lung

2015

A variety of diseases can lead to loss of lung tissue. Currently, this can be treated only symptomatically. In mice, a complete compensatory lung growth within 21 days after resection of the left lung can be observed. Understanding and transferring this concept of compensatory lung growth to humans would greatly improve therapeutic options. Lung growth is always accompanied by a process called angiogenesis forming new capillary blood vessels from preexisting ones. Among the processes during lung growth, the formation of transluminal tissue pillars within the capillary vessels (intussusceptive pillars) is observed. Therefore, pillars can be understood as an indicator for active angiogenesis …

Administración liberal y corrupción política: el conflicto del Real Colegio de San Pablo con el Instituto Provincial de Valencia

2015

The present paper examines the Spanish public schools inside the liberal educative system doing a detailed analysis of the Real Colegio de San Pablo of Valencia. The article studies this Real Colegio in order to point out the conflict provoked by political corruption, since Juan Bravo Murillo, a Spanish minister, appointed relatives to direction posts against the desires of Antonio Gil de Zárate, the founder of the Spanish liberal educative system. In this case, the struggle between personal interest of politicians and the necessities of the new and modern administration were related to the problematic issue of the model of high schools established by the State: elitist public schools or op…

Solemne acte d'investidura com a doctor 'Honoris Causa' del Sr. Manuel Elkin Patarroyo Murillo

1997

Solemne acte d'investidura com a Dr. Honoris Causa de l'excel·lentíssim Sr. Manuel Elkin Patarroyo Murillo en el paranimf de la Universitat de València.

Green tea extract assisted low-temperature pasteurization to inactivate enteric viruses in juices.

2020

The current popularity of minimally processed foods is an opportunity for natural antimicrobial agents to be combined with mild heat treatments to act synergistically in reducing viral foodborne pathogens. Viral inactivation by heat-treatments (at 25, 40, 50 and 63 °C for 30 min) combined with aged green tea extract (aged-GTE) was initially evaluated in phosphate buffered saline (PBS) against murine norovirus (MNV-1) and hepatitis A virus (HAV) by cell culture, and against human norovirus by in situ capture RT-qPCR. The combination of aged-GTE and heat treatment at 50 °C for 30 min exerted strong antiviral activity, reducing by more than 5 log MNV-1 infectivity in PBS. Heating at 40 °C for …

The viral chemokine MCK-2 of murine cytomegalovirus promotes infection as part of a gH/gL/MCK-2 complex.

2013

Human cytomegalovirus (HCMV) forms two gH/gL glycoprotein complexes, gH/gL/gO and gH/gL/pUL(128,130,131A), which determine the tropism, the entry pathways and the mode of spread of the virus. For murine cytomegalovirus (MCMV), which serves as a model for HCMV, a gH/gL/gO complex functionally homologous to the HCMV gH/gL/gO complex has been described. Knock-out of MCMV gO does impair, but not abolish, virus spread indicating that also MCMV might form an alternative gH/gL complex. Here, we show that the MCMV CC chemokine MCK-2 forms a complex with the glycoprotein gH, a complex which is incorporated into the virion. We could additionally show that mutants lacking both, gO and MCK-2 are not ab…

Cryptic Diversity in Mongolian Vespertilionid Bats (Vespertilionidae, Chiroptera, Mammalia). Results of the Mongolian-German Biological Expeditions S…

2012

In contrast to the Eastern Palaearctic region a high degree of cryptic diversity was discovered among temperate bats of the Western Palaearctic region in the last ten years. Climatic oscillations caused severe changes in the distribution of species throughout the Palaearctic region during the Pleistocene. Exploring multiple taxa can help to understand general evolutionary differentiation processes. In the present study genetic variation within and among 94 Mongolian vespertilionid bats of six genera (Hypsugo, Eptesicus, Vespertilio, Myotis, Plecotus, and Nyctalus) was screened by sequencing a 798 bp fragment of the mitochondrial ND1 gene and then subsequently compared with those of Western …

I RODITORI DI CAVA MONTICINO (BRISIGHELLA, RA)

2021

Rodents are the most abundant group of small mammals occurring in Brisighella deposits. They are represented by 12 species in total, among which 2 hamsters (Apocricetus cf. barrierei and Ruscinomys cf. lasallei), 2 dormice (Muscardinus sp. and Myomimus sp.), 1 porcupine (Hystrix (Hystrix) depereti), 2 sciurids (Atlantoxerus cf. rhodius and Hylopetes sp.) and 5 species of muridae (Apodemus cf. gudrunae, Centralomys benericettii, Occitanomys sp, Paraethomys meini and Stephanomys debruijni). This association suggests a relatively dry open environment, interrupted by forest environment with more or less dense underground.

AML-associated Flt3 kinase domain mutations show signal transduction differences compared with Flt3 ITD mutations

2005

Activating mutations of Flt3 are found in approximately one third of patients with acute myeloid leukemia (AML) and are an attractive drug target. Two classes of Flt3 mutations occur: internal tandem duplications (ITDs) in the juxtamembrane and point mutations in the tyrosine kinase domain (TKD). We and others have shown that Flt3-ITD induced aberrant signaling including strong activation of signal transducer and activator of transcription 5 (STAT5) and repression of CCAAT/estradiol-binding protein α (c/EBPα) and Pu.1. Here, we compared the signaling properties of Flt3-ITD versus Flt3-TKD in myeloid progenitor cells. We demonstrate that Flt3-TKD mutations induced autonomous growth of 32D ce…

The effect of essential oils on norovirus surrogates

2013

Abstract Essential oils (EOs) have long been applied as flavoring agents in foods, and due to their content in antimicrobial compounds, they have potential as natural agents for food preservation. In this study the effect of three EOs, clove, oregano and zataria, was evaluated on the infectivity of norovirus surrogates, i.e. feline calicivirus (FCV) and murine norovirus (MNV). Different concentrations of EOs were individually mixed with each virus at titers of ca. 7–8 log TCID 50 /ml and incubated for 2 h at 4 °C and 37 °C. The infectivity of the recovered viruses after triplicate treatments was evaluated by cell-culture assays. 2% of oregano EO at 37 °C decreased the FCV titers by 3.75 log…