Search results for "Muscle strength"

Impaired geometric properties of tibia in older women with hip fracture history.

2007

This study evaluated side-to-side differences in tibial mineral mass and geometry in women with previous hip fracture sustained on average 3.5 years earlier. Both tibial mineral mass and geometry were found to be reduced in the fractured leg. INTRODUCTION: The purpose of this study was to evaluate side-to-side differences in tibial mineral mass and geometry after hip fracture and to assess the determinants of such differences. METHODS: Thirty-eight 60- to 85-year-old women with a previous hip fracture and 22 same-aged control women without fractures participated in the study. Bone characteristics of the distal tibia and tibial shaft of both legs were assessed using pQCT in order to compare …

Decreasing muscle performance associated with increasing disease activity in patients with rheumatoid arthritis

2018

Objectives Increasing evidence suggests that inflammation has a detrimental effect on muscle strength. Our objective was to analyse the association between muscle performance and different disease activity levels in patients with rheumatoid arthritis (RA). Method A total of 199 consecutive outpatients were subject to cross-sectional assessment. Measurements of grip strength, endurance of the upper and lower limbs and trunk strength were combined as a muscle performance composite score (MPCS), using a standardised method. The disease activity for 28 joints (DAS28), radiographs of small joints (Larsen score), rheumatoid factor, body mass index (BMI), comorbidities and anti-rheumatic drugs wer…

Mobility and its decline in old age : determinants and associated factors

2013

Age and Muscle Function Are More Closely Associated With Intracellular Magnesium, as Assessed by

2019

Total serum magnesium is a common clinical measurement for assessing magnesium status; however, magnesium in blood represents less than 1% of the body’s total magnesium content. We measured intramuscular ionized magnesium by phosphorus magnetic resonance spectroscopy (31P-MRS) and tested the hypothesis that this measure better correlates with skeletal muscle function and captures more closely the effect of aging than the traditional measure of total serum magnesium. Data were collected from 441 participants (age 24–98 years) in the Baltimore Longitudinal Study of Aging (BLSA), a study of normative aging that encompasses a broad age range. Results showed that intramuscular ionized magnesium …

Velocity-based resistance training: do women need greater velocity loss to maximize adaptations?

2021

Abstract Purpose Men and women typically display different neuromuscular characteristics, force–velocity relationships, and differing strength deficit (upper vs. lower body). Thus, it is not clear how previous recommendations for training with velocity-loss resistance training based on data in men will apply to women. This study examined the inter-sex differences in neuromuscular adaptations using 20% and 40% velocity-loss protocols in back squat and bench press exercises. Methods The present study employed an 8-week intervention (2 × week) comparing 20% vs. 40% velocity-loss resistance training in the back squat and bench press exercises in young men and women (~ 26 years). Maximum strengt…

A Polygenic Risk Score for Hand Grip Strength Predicts Muscle Strength and Proximal and Distal Functional Outcomes among Older Women

2022

Purpose Hand grip strength (HGS) is a widely used indicator of overall muscle strength and general health. We computed a polygenic risk score (PRS) for HGS, and examined, whether it predicted muscle strength, functional capacity and disability outcomes. Methods Genome-wide association study summary statistics for HGS from the Pan-UK Biobank was utilized. PRSs were calculated in the Finnish Twin Study on Aging (N = 429 women, 63–76 years). Strength tests included HGS, isometric knee extension, and ankle plantar flexion strength. Functional capacity was examined with the Timed Up and Go, six-minute and 10-meter walk tests, and dual-task tests. Disabilities in the basic (ADL) and instrumental …

Physical Performance During the Menopausal Transition and the Role of Physical Activity

2020

Abstract Background To examine longitudinal changes in physical performance during the menopausal transition and the role of physical activity (PA) in these changes. Methods Based on follicle-stimulating hormone levels and bleeding diaries, women (47–55 years) were classified as early (n = 89) and late perimenopausal (n = 143) and followed prospectively until postmenopausal status, with mean duration of 17.5 and 13.8 months, respectively. Physical performance was measured by handgrip force, knee extension torque, vertical jumping height, maximal walking speed, and 6-minute walking distance. Physical activity was self-reported and categorized as inactive, low, medium, and high. Longitudinal …

Long-term strength and balance training prevents mobility decline among community-dwelling people aged 75 and older

2016

High functional capacity of muscle strength and balance in older persons promotes independent mobility and prevents functional decline below the disability threshold. This dissertation explored the effects of strength and balance training (SBT) as part of a multimodal geriatric intervention on physical functioning and health-related factors associated with training participation in a community-dwelling population aged 75 years and over. This study is a part of the Geriatric Multidisciplinary Strategy for the Good Care of the Elderly (GeMS) project conducted from 2004 to 2007 in Kuopio, Finland. Participants were randomized into an intervention (n=339) and control group (n=312). The individu…