Search results for "Muscle"

showing 10 items of 3397 documents

Avoidant coping, verbal-autonomic response dissociation and pain tolerance

2006

Higher autonomic reactivity relative to self-reported discomfort, often found in repressors and avoidant copers might be associated with a diminished perception of bodily symptoms. This study aimed at relating such so-called verbal-autonomic response dissociation to pain tolerance. Eighty-five volunteers underwent a public speaking task and a cold pressor test. Heart rate and negative affect in response to the speech, and pain ratings and facial muscle responses for the cold pressor were obtained. A dissociation score was calculated for each individual in response to speech, thereby subtracting standardized changes in negative affect from standardized changes in heart rate. Response dissoci…

medicine.medical_specialtyDissociation (neuropsychology)Pain tolerancemedia_common.quotation_subjectPublic Health Environmental and Occupational HealthCold pressor testGeneral MedicineGeneral ChemistryAudiologybehavioral disciplines and activitiesDevelopmental psychologyAvoidant copingFacial musclesmedicine.anatomical_structurePerceptionHeart ratemedicinePain perceptionPsychologyApplied Psychologymedia_commonPsychology & Health
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D1 receptors play a major role in the dopamine modulation of mouse ileum contractility

2010

Since the role of dopamine in the bowel motility is far from being clear, our aim was to analyse pharmacologically the effects of dopamine on mouse ileum contractility. Contractile activity of mouse ileum was examined in vitro as changes in isometric tension. Dopamine caused a concentration-dependent reduction of the spontaneous contraction amplitude of ileal muscle up to their complete disappearance. SCH-23390, D1 receptor antagonist, which per se increased basal tone and amplitude of spontaneous contractions, antagonized the responses to dopamine, whilst sulpiride or domperidone, D2 receptor antagonists, were without effects. The application of both D1 and D2 antagonists had additive effe…

medicine.medical_specialtyDopamineMouse ileumD1 receptorIn Vitro TechniquesSettore BIO/09 - FisiologiaEnteric Nervous SystemPotassium channelsContractilityMicechemistry.chemical_compoundDopamine receptor D1IleumDopamineInternal medicineDopamine receptor D2medicineAnimalsPharmacologySCH-23390Dose-Response Relationship DrugReceptors Dopamine D1BenzazepinesAdenosine receptorContractile activityD2 receptorDopamine D2 Receptor AntagonistsEndocrinologychemistryDopamine receptorDopamine AntagonistsEndogenous agonistAdenylyl CyclasesMuscle Contractionmedicine.drugPharmacological Research
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Antihistaminic and anticholinergic activities of mequitazine in comparison with clemizole

1988

Abstract The antihistamine and anticholinergic properties of mequitazine have been investigated and compared with those of clemizole. Both mequitazine and clemizole antagonized the effect of histamine in guinea-pig ileum competitively, the pA2 values calculated by Schild plot were 9.95 ± 0.44 for mequitazine and 10.54 ± 0.44 for clemizole. Mequitazine at 10−7 M produced a parallel shift of the dose-response curve to acetylcholine in the rat duodenum, clemizole and the lower doses of mequitazine failed to modify the effect of acetylcholine. The potency of mequitazine and clemizole as H1-histamine blockers is similar, but only mequitazine at highest concentration used showed anticholinergic a…

medicine.medical_specialtyDuodenummedicine.drug_classmedicine.medical_treatmentGuinea PigsPharmaceutical ScienceIn Vitro TechniquesBiologyParasympatholyticchemistry.chemical_compoundPhenothiazinesInternal medicinemedicineAnticholinergicAnimalsPotencyMequitazinePharmacologyParasympatholyticsMuscle SmoothRats Inbred StrainsAcetylcholineRatsClemizoleSchild regressionEndocrinologychemistryHistamine H1 AntagonistsBenzimidazolesAntihistamineHistamineHistamineMuscle Contractionmedicine.drugJournal of Pharmacy and Pharmacology
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Fatigue effects of marathon running on neuromuscular performance

2007

Nine experienced endurance runners performed individual marathon runs that involved several tests of neuromuscular performance before, during and after the marathon. The tests were performed with special force platform and dynamometer techniques. The results showed an overall decrease in performance from the marathon. The maximal sprint velocity decreased parabolically during the marathon, reaching the final value of 84% of the pre-marathon one. Similarly, the other test results after marathon indicated that maximal isometric knee extension torque was 78%, the performance in a special rebound test (drop jump) 84% and the 5-jump performance 92% of the pre-marathon values. These reductions we…

medicine.medical_specialtyDynamometerbusiness.industryPhysical Therapy Sports Therapy and RehabilitationIsometric exerciseMuscle stiffnessStretch shortening cyclePhysical medicine and rehabilitationSprintJumpPhysical therapyMedicineOrthopedics and Sports MedicineForce platformGround reaction forcebusinesshuman activitiesScandinavian Journal of Medicine & Science in Sports
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Secondary reduction in calpain 3 expression in patients with limb girdle muscular dystrophy type 2B and Miyoshi myopathy (primary dysferlinopathies).

2000

Made available in DSpace on 2016-10-10T03:52:18Z (GMT). No. of bitstreams: 5 Secondary reduction in calpain 3 expression in patients with limb girdle muscular dystrophy type 2B and Miyoshi myopathy.pdf: 167085 bytes, checksum: b445ec059ea2d0f06bd4fa913354872a (MD5) license_url: 52 bytes, checksum: 2f32edb9c19a57e928372a33fd08dba5 (MD5) license_text: 24259 bytes, checksum: f1f24f769b03eb8f9cd3f53c1090841c (MD5) license_rdf: 24658 bytes, checksum: 9d3847733d3c0b59c7c89a1d40d3d240 (MD5) license.txt: 1887 bytes, checksum: 445d1980f282ec865917de35a4c622f6 (MD5) Previous issue date: 2000 Dysferlin is the protein product of the gene (DYSF) that is defective in patients with limb girdle muscular dy…

medicine.medical_specialtyDysferlinopathyDNA Mutational AnalysisMuscle ProteinsMuscular DystrophiesWestern blottingDysferlinMuscular DiseasesLamininInternal medicinemedicineMissense mutationCalpain 3HumansMuscular dystrophyDysferlinGenetics (clinical)Geneticsbiologybusiness.industryCalpainMembrane ProteinsCalpainmedicine.diseaseMuscular dystrophyLaminin alpha 2EndocrinologyMuscle proteinsNeurologyPediatrics Perinatology and Child Healthbiology.proteinNeurology (clinical)LamininbusinessMerosinLimb-girdle muscular dystrophyNeuromuscular disorders : NMD
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Complications of botulinum toxin and fillers: A narrative review

2019

Background Cosmetic surgery and esthetic procedures have become a billion dollar industry owing to the ever-growing demand of the population to stay young. The injectable treatments including fillers and botulinum toxin have become highly popular because of their quick, predictable and lasting results in the management of facial wrinkles and rejuvenation. Although these treatment modalities are relatively safe, they are associated with certain side effects. Aims In this review, we will focus on the complications of fillers and botulinum toxin. Patients/methods The literature research considered published journal articles (clinical trials or scientific reviews). Studies were identified by se…

medicine.medical_specialtyEcchymosisPopulationMEDLINEFacial MusclesCosmetic TechniquesDermatologyPain ProceduralInjections030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineDermal FillersHumansMedicineBotulinum Toxins Type AeducationIntensive care medicineAdverse effecteducation.field_of_studybusiness.industryBotulinum toxinInjection Site ReactionClinical trialFacial AsymmetryNeuromuscular Agents030220 oncology & carcinogenesisBrow ptosisNarrative reviewEyebrowsmedicine.symptombusinessmedicine.drugJournal of Cosmetic Dermatology
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The deltoid muscle: an electromyographical analysis of its activity in arm abduction in various body postures

1992

We have carried out an electromyographical examination of the activity of five different regions of the deltoid muscle during abduction/adduction in various body postures with different biomechanical actions of arm gravity. The results show that the deltoid action is highly differentiated in its different regions and is not restricted only to the generation of an abducting moment in the shoulder joint. There is obviously a biomechanical contribution, mainly by its spinal and clavicular regions, to the stabilization of the glenohumeral joint and to the control of the selected plane of abduction.

medicine.medical_specialtyElectrodiagnosisMovementPostureDeltoid curveElectromyographyBiomechanical PhenomenaPhysical medicine and rehabilitationDeltoid musclemedicineHumansOrthopedics and Sports Medicinemedicine.diagnostic_testElectromyographyBody posturebusiness.industryMusclesAnatomyBiomechanical Phenomenabody regionsmedicine.anatomical_structureArmSurgeryShoulder jointmedicine.symptombusinesshuman activitiesGravitationMuscle ContractionMuscle contractionInternational Orthopaedics
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Electromyographic Activity Evolution of Local Twitch Responses During Dry Needling of Latent Trigger Points in the Gastrocnemius Muscle: A Cross-Sect…

2019

Abstract Objective Trigger points (TrPs) are hypersensitive spots within taut bands of skeletal muscles that elicit referred pain and motor changes. Among the variety of techniques used for treating TrPs, dry needling is one of the most commonly applied interventions. The question of eliciting local twitch responses (LTRs) during TrP dry needling is unclear. Our main aim was to investigate the evolution of the electromyographic (EMG) peak activity of each LTR elicited during dry needling into latent TrPs of the gastrocnemius medialis muscle. Methods Twenty asymptomatic subjects with latent TrPs in the gastrocnemius medialis muscle participated in this cross-sectional study. Changes in EMG s…

medicine.medical_specialtyElectromyographyAsymptomatic03 medical and health sciencesGastrocnemius muscle0302 clinical medicineInternal medicinemedicineHumansMuscle SkeletalMyofascial Pain Syndromes030222 orthopedicsDry needlingReferred painmedicine.diagnostic_testbusiness.industryTrigger PointsGeneral MedicineConfidence intervalData at RestCross-Sectional StudiesAnesthesiology and Pain MedicineDry NeedlingCardiologyNeurology (clinical)Analysis of variancemedicine.symptombusiness030217 neurology & neurosurgeryPain Medicine
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Effects of endothelin-1 on the cerebrovascular bed of the goat.

1991

Abstract The aim of the present study was to analyze the effects of endothelin-1 (ET-1) in the cerebrovascular bed of the goat, the importance of endothelial integrity and the contribution of extracellular Ca2+ to these responses. We measured isometric tension and 45Ca2+ uptake in isolated middle cerebral arteries, and cerebral blood flow (CBF) in unanesthetized animals. ET-1 elicited concentration-dependent contractions which were potentiated in arteries without endothelium. Ca2+-free medium and nicardipine inhibited, and Bay K 8644 potentiated the ET-1-induced contractions. ET-1 enhanced 45Ca2+ uptake in isolated arteries. Injections of ET-1 directly into the cerebral circulation decrease…

medicine.medical_specialtyEndotheliumCerebral arteriesNicardipineIn Vitro TechniquesMuscle Smooth VascularCerebral circulationNicardipineInternal medicinemedicine.arteryIsometric ContractionmedicineAnimalsPharmacologyChemistryCalcium RadioisotopesEndothelinsGoatsAnatomy3-Pyridinecarboxylic acid 14-dihydro-26-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)- Methyl esterEndothelin 1Acetylcholinemedicine.anatomical_structureEndocrinologyCerebral blood flowCerebrovascular CirculationMiddle cerebral arteryPotassiumCalciumFemaleBlood vesselmedicine.drugEuropean journal of pharmacology
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Isoflavones and cardiovascular disease

2010

The specific profile of estrogens on cardiovascular risk, with limiting action on atherogenesis but a less clear protection on cardiovascular episodes, might be improved by other agonists of the estrogen receptor, such as isoflavones. By using a systematic search based on the electronic Medline database plus a hand-search of reference lists of selected review papers, we reviewed the rapidly growing body of experimental and clinical data that, on average, follow a pattern of benefit rather similar to estrogens. Experimental models have used endothelial and vascular smooth muscle cells, isolated arteries, and live animals, including monkeys. The clinical evidence arises from studies on the li…

medicine.medical_specialtyEndotheliumPhysiologyProstacyclinMuscle Smooth VascularGeneral Biochemistry Genetics and Molecular Biologychemistry.chemical_compoundInsulin resistanceLipid oxidationInternal medicineAnimalsHumansMedicineEvidence-Based Medicinemedicine.diagnostic_testbusiness.industrySoy FoodsObstetrics and GynecologyIsoflavonesLipid Metabolismmedicine.diseaseIsoflavonesPostmenopauseMenopauseEndocrinologymedicine.anatomical_structurechemistryCardiovascular DiseasesHemostasisSoybean ProteinsWomen's HealthFemaleEndothelium VascularbusinessLipid profilemedicine.drugMaturitas
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