Search results for "Muscle"

Studies using pharmacological blockade of muscle afferents provide new insights into the neurophysiology of perceived exertion

2016

The increase in blood pressure observed during physical activities is exaggerated in patients with hypertension, exposing them to a higher cardiovascular risk.Neural signals from the skeletal muscles appear to be overactive, resulting in this abnormal response in hypertensive patients.In the present study, we tested whether the attenuation of these neural signals in hypertensive patients could normalize their abnormal increase in blood pressure during physical activity.Attenuation of the neural signals from the leg muscles with intrathecal fentanyl injection reduced the blood pressure of hypertensive men during cycling exercise to a level comparable to that of normotensive men.Skeletal musc…

The significance of the triceps surae muscle action as a determinant in the biomechanical genesis of ski fall injuries

1985

In an epidemiologic study of 700 ski fall injuries YOUNG /1/ established a classification of the different fall modes involved. In more than 60 % of all falls that lead to an injury he found a forward bending motion of the body which is frequently coupled with a twisting of the body around the lower extremity. This clearly shows the importance of the forward motion component of the skier’s body in ski fall traumatology. The type of injury and its location depend on the action of the ski binding system. If the binding does not release in a ski fall, the fraction of injuries in the lower extremity amounts to nearly 100 %. If the binding does release, however, the injuries ocurring in this cas…

MECHANISMS OF TENSION DEVELOPMENT INDUCED BY MONENSIN IN GUINEA-PIG AORTA : EFFECTS OF VERAPAMIL, OUABAIN, PRAZOSIN AND GLIBENCLAMIDE

1993

The influence of monensin (10 µmol/L) alone and in the presence of verapamil (3 µmol/L) or ouabain (1 mmol) and prazosin (1 µmol/L) or glibenclamide (10 µmol/L) were studied on the muscle tension of guinea pig aorta. Changes in tissue sodium, potassium and calcium ion contents of the aortic muscle produced by monensin in the presence of prazosin were evaluated. Monensin in normal Tyrode's solution containing prazosin caused an increase in the resting tension followed by a decrease and returned to normal values. Verapamil reduced the muscle tension induced by monensin. After ouabain, monensin induced sustained increase in the resting tension. Glibenclamide partially reversed the relaxant pha…

Diamond-Shaped Mini-Craniotomy: A New Concept in Neurosurgery

2021

Abstract Background We describe, step by step, a modified, less invasive, diamond-shaped mini-craniotomy that optimizes dural opening and can be performed in elderly patients affected by acute subdural or intracerebral hematomas, in therapy with antiplatelets or anticoagulants. Methods We retrospectively analyzed the clinical records of 67 patients (mean age of 78.5 years) treated in our institution, during a period of 10 years, with this novel diamond-shaped craniotomy. Seventeen patients were treated for intracerebral hemorrhage and 50 patients for acute subdural hematomas. All the patients were in therapy with antiplatelets or anticoagulants. Results Approach-related complications were n…

A Preliminary Study on Cranio-Facial Characteristics Associated with Minor Neurological Dysfunctions (MNDs) in Children with Autism Spectrum Disorder…

2020

Background. Craniofacial anomalies and minor neurological dysfunction (MNDs) have been identified, in literature, as risk factors for neurodevelopmental disorders. They represent physical indicators of embryonic development suggesting a possible contributory role of complications during early, even pre-conceptional, phases of ontogeny in autism spectrum disorders (ASD). Limited research has been conducted about the co-occurrence of the two biomarkers in children with ASD. This study investigates the associative patterns of cranio-facial anomalies and MNDs in ASD children, and whether these neurodevelopmental markers correlate with intensity of ASD symptoms and overall functioning. Methods. …

Influencia de la masa muscular en el VO2max en atletismo, triatlón y natación

2019

El objetivo del estudio es conocer cómo influye la masa muscular de la extremidad inferior y superior en el volumen de oxigeno máximo por kilogramo de masa muscular (VO2max/Kgmus/min) en jóvenes deportistas en función de su especialidad deportiva y grupo de edad. La muestra está compuesta por 400 deportistas de ambos sexos del Centro de Tecnificación de Cheste (Valencia) clasificados en 3 grupos de edad: <12-13, 14-16 y 17-20 años, y de especialidades deportivas de resistencia. Los datos fisiológicos se han obtenido de un test ergoespirométrico incremental en rampa (protocolo Wasserman) y los datos antropométricos del protocolo ISAK. Los resultados derivados del Análisis de Varianza (ANO…

Plyometric muscular action tests in judo- and non-judo athletes

2011

The majority of explosive actions during the Judo fight occur when the athlete is trying to overcome his/her adversary via rapid execution(s) of (isolated or chained) technical manoeuvres. The aim of this study was to compare the results of two plyometric muscular action tests (i.e., Squat Jump – SJ, and Countermovement Jump – CMJ) between judoand non-judoathletes. The investigation involved a cross-sectional examination of 102 subjects (age, 21.9 ± 3.4 years) divided into 3 performance groups: a) Senior top elite judo athletes (n = 50), b) Junior elite judo athletes (n = 26) and c) Adult non-judo athletes (n = 26). Thirteen biomechanical variables (including jump height, velocity, power, f…

Validity, Reliability, and Sensitivity to Change of DiCI for the Strength Measurement of Knee and Hip Muscles

2020

Many professionals use the handheld dynamometers (HHDs) to assess isometric strength. This study aimed to evaluate the validity, reliability, and sensitivity to change of a DiCI (a new HHD) for the...

2021

The aim of this study was to investigate whether recovery from eccentric squat exercise varies depending on age and to assess whether the use of a mixed-method recovery (MMR) consisting of cold water immersion and compression tights benefits recovery. Sixteen healthy and resistance-trained young (age, 22.1±2.1years; N=8) and master male athletes (age, 52.4±3.5years; N=8), who had a similar half squat 1-repetition maximum relative to body weight, completed two identical squat exercise training sessions, separated by a 2-week washout period. Training sessions were followed by either MMR or passive recovery (PR). Internal training loads [heart rate and blood lactate concentration (BLa)] were r…

SFRR-E Young Investigator AwardeeαB-crystallin modulation after acute exercise in skeletal muscle: the role of oxidative stress and fiber composition.

2015

αB-crystallin (CRYAB) is a member of the small heat shock proteins implicated in various biological functions, particularly in skeletal muscle where it is involved in adaptive remodelling processes, activation of gene transcription and stabilization of nascent proteins.In this research we analysed αB-crystallin' response in mouse gastrocnemius at 15' and 30' of recovery from an acute aerobic exercise (1hour), correlating its modulation with oxidative stress level and fiber composition, red (RG) and white gastrocnemius (WG).We found for the first time that the acute exercise lead to a short term, specific increase of phospho-αB-crystallin level (pCRYAB) in the RG, while no changes were obser…