Search results for "Muscle"

showing 10 items of 3397 documents

Differential contributions of ankle plantarflexors during submaximal isometric muscle action: A PET and EMG study

2014

Abstract The objective of this study was to investigate the relative contributions of superficial and deep ankle plantarflexors during repetitive submaximal isometric contractions using surface electromyography (SEMG) and positron emission tomography (PET). Myoelectric signals were obtained from twelve healthy volunteers (27.3±4.2yrs). A tracer ([ 18 F]-FDG) was injected during the exercise and PET scanning was done immediately afterwards. The examined muscles included soleus (Sol), medial gastrocnemius (MG), lateral gastrocnemius (LG), and flexor hallucis longus (FHL). It was found that isometric maximal voluntary contraction (MVC) force, muscle glucose uptake (GU) rate, and SEMG of variou…

AdultMaleBiophysicsNeuroscience (miscellaneous)Isometric exerciseElectromyographyYoung AdultMuscle actionIsometric ContractionHealthy volunteersmedicineHumansExercise physiologyMuscle Skeletalta315ExerciseLegArthrometry Articularmedicine.diagnostic_testElectromyographybusiness.industryBiomechanicsAnatomymusculoskeletal systemMagnetic Resonance ImagingHealthy VolunteersGlucosemedicine.anatomical_structureFlexor hallucis longusPositron-Emission TomographyFemaleNeurology (clinical)AnkleAnklebusinessNuclear medicineJournal of Electromyography and Kinesiology
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Association between muscular strength and cognition in people with major depression or bipolar disorder and healthy controls

2018

Importance Objective physical fitness measures, such as handgrip strength, are associated with physical, mental, and cognitive outcomes in the general population. Although people with mental illness experience reduced physical fitness and cognitive impairment, the association between muscular strength and cognition has not been examined to date. Objective To determine associations between maximal handgrip strength and cognitive performance in people with major depression or bipolar disorder and in healthy controls. Design, Setting, and Participants In a multicenter, population-based study conducted between February 13, 2005, and October 1, 2010, in the United Kingdom, cross-sectional analys…

AdultMaleBipolar DisorderPhysical fitnessMuscle Strength DynamometerPhysical strength03 medical and health sciences0302 clinical medicineCognitionHand strengthmedicineHumansCognitive Dysfunction030212 general & internal medicineBipolar disorderMuscle StrengthAgedOriginal Investigationhandgrip strengthDepressive Disorder MajorHand Strengthbusiness.industryMiddle AgedMental illnessmedicine.diseaseHealthy VolunteersPsychiatry and Mental healthCross-Sectional StudiesSchizophreniaPhysical FitnessCase-Control StudiesdepressionMajor depressive disorderFemalebusinessNeurocognitive030217 neurology & neurosurgeryClinical psychology
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Diet high in protein-rich foods with structured sport activity may be useless to lose fat mass and maintain fat-free mass

2020

Background The aim of this study was to demonstrate that a normal protein diet along with minimal sports activity can be enough to lose fat mass and maintain muscle mass. Methods All participants were prescribed a hypocaloric nutritionally balanced Mediterranean-style diet tailored to the individual for 8 weeks. Body composition and energy expenditure were measured. Sedentary patients (G1) were only recommended to perform minimal aerobic training, while sport subjects (G2) were prescribed structured physical activity and higher calorie and protein contents in the diet. Results There were no significant differences between the two groups for any of the measured parameters. Conclusions The mo…

AdultMaleCalorieEndocrinology Diabetes and MetabolismPhysiologyMuscle massSettore MED/49Fat massProtein contentYoung Adult03 medical and health sciences0302 clinical medicineSettore MED/13Fat free massWeight LossInternal MedicineHumansAerobic exerciseMedicineNormal proteinMuscle SkeletalExerciseNutrition and Dieteticsbusiness.industryGastroenterologyProteinsEnergy metabolismOverweightDietAdipose TissueEnergy expenditure030220 oncology & carcinogenesisBody CompositionDiet High-ProteinFemale030211 gastroenterology & hepatologybusinessSports
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Genome-Wide Association Studies of the PR Interval in African Americans.

2011

The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a general paucity of GWA studies in individuals of African ancestry. We performed GWA studies in African American individuals from four cohorts (n = 6,247) to identify genetic variants associated with PR interval duration. Genotyping was performed using the Affymetrix 6.0 microarray. Imputation was p…

AdultMaleCancer ResearchMuscle ProteinsSingle-nucleotide polymorphismGenome-wide association studyQH426-470030204 cardiovascular system & hematologyBiologyGenetics and Genomics/Complex TraitsPolymorphism Single NucleotideSodium ChannelsWhite PeopleNAV1.5 Voltage-Gated Sodium ChannelNAV1.8 Voltage-Gated Sodium Channel03 medical and health sciencesElectrocardiography0302 clinical medicineAsian PeopleCardiovascular Disorders/Arrhythmias Electrophysiology and PacingGeneticsSNPHumansCardiac and Cardiovascular SystemsPR intervalInternational HapMap ProjectMyeloid Ecotropic Viral Integration Site 1 ProteinMolecular BiologyGenotypingGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyAgedGeneticsHomeodomain Proteins0303 health sciencesArrhythmias CardiacHeart-rate;Atherosclerosis risk; Genetic-analysis; Common variants; Design; Populations; Objectives; Conduction; Disease; TwinsMiddle AgedNeoplasm ProteinsMinor allele frequencyBlack or African AmericanAtrioventricular NodeFemaleT-Box Domain ProteinsImputation (genetics)Research ArticleGenome-Wide Association Study
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Parotid sialosis: morphometrical analysis of the glandular parenchyme and stroma among diabetic and alcoholic patients

2009

J Oral Pathol Med (2010) 39: 10–15 Background:  Among the agents that cause parotid sialosis, diabetes mellitus type 2 and chronic alcoholism are included. In this study, the morphometrical modifications in the diabetic parotid sialosis were determined to compare them with the histopathological characteristics of alcoholic parotid sialosis. Methods:  Five parotid biopsy samples obtained from patients with diabetic sialosis, 12 samples from patients with alcoholic sialosis and seven from individuals without these pathologies (control group) were analyzed. A morphometrical study of parotid parenchyme and stroma, using a digital image analyzer attached to an optical microscope, was carried out…

AdultMaleCancer ResearchPathologymedicine.medical_specialtyBiopsyAdipose tissueCell CountEpitheliumPathology and Forensic MedicineMuscle hypertrophystomatognathic systemLiver Cirrhosis AlcoholicDiabetes mellitusParenchymaBiopsyImage Processing Computer-AssistedmedicineHumansSalivary DuctsAgedAged 80 and overMicroscopymedicine.diagnostic_testbusiness.industryMiddle Agedmedicine.diseaseSialadenitisParotid glandAlcoholismSerous fluidmedicine.anatomical_structureAdipose TissueDiabetes Mellitus Type 2OtorhinolaryngologyPeriodonticsFemaleParotid DiseasesOral SurgerybusinessJournal of Oral Pathology & Medicine
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Expression of cysteine proteinases cathepsins B and K and of cysteine proteinase inhibitor cystatin C in giant cell tumor of tendon sheath.

2001

The expression of cysteine proteinases cathepsins B and K and of the endogenous inhibitor of cysteine proteinases, cystatin C, was investigated in tissue specimens of patients with giant cell tumor of tendon sheath (GCTTS). Expression of both enzymes was examined by immunohistochemistry in tissue specimens of 14 patients with GCTTS. Applying double-labeling techniques, the coexpression of cathepsin B and its major endogenous inhibitor cystatin C was additionally studied. Cells expressing the respective proteins were further characterized with the macrophage markers HAM56 and anti-CD68 (clone PG-M1). Cathepsin B could be detected in numerous HAM56-positive mononuclear cells (MC), but only in…

AdultMaleCathepsin KAntigens Differentiation MyelomonocyticCathepsin ECell CountCathepsin FBiologyCysteine Proteinase InhibitorsGiant CellsCathepsin BPathology and Forensic MedicineCathepsin CCathepsin BImmunoenzyme TechniquesTendonsCathepsin OCathepsin HAntigens CDCathepsin L1HumansCystatin CCathepsin SAgedMuscle NeoplasmsGiant Cell TumorsAntibodies MonoclonalMiddle AgedMolecular biologyCathepsinsCystatinsBiochemistryLeukocytes MononuclearFemaleModern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
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Calf Blood Compound (CFC) and Homeopathic Drug Induce Differentiation of Primary Human Skeletal Muscle Cells.

2019

AbstractThe use of injections to treat structural muscle injuries is controversially discussed. In our controlled in vitro study, we investigated the biological impact of Actovegin and Traumeel alone and in combination on primary human skeletal muscle cells. Cells were characterized by immunofluorescence staining for myogenic factor 5 (Myf5) and MyoD, and cultured with or without Actovegin and / or Traumeel. The effects of these agents were assayed by cell viability and gene expression of the specific markers MyoD, Myf5, neural adhesion molecule (NCAM), and CD31. Myotube formation was determined by myosin staining. Neither Actovegin nor Traumeel showed toxic effects or influenced cell viabi…

AdultMaleCell SurvivalMuscle Fibers SkeletalDown-RegulationPhysical Therapy Sports Therapy and RehabilitationHeme030204 cardiovascular system & hematologyPharmacologyMyoD03 medical and health sciences0302 clinical medicineIn vivoGene expressionMyosinmedicineHumansOrthopedics and Sports MedicineViability assayCells CulturedAgedMyoD ProteinMineralsDose-Response Relationship DrugChemistryPlant ExtractsSkeletal muscleCell Differentiation030229 sport sciencesMiddle Agedmusculoskeletal systemCD56 AntigenPlatelet Endothelial Cell Adhesion Molecule-1medicine.anatomical_structureNeural cell adhesion moleculeMYF5Myogenic Regulatory Factor 5International journal of sports medicine
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Understanding the effect of window length and overlap for assessing sEMG in dynamic fatiguing contractions: A non-linear dimensionality reduction and…

2020

The Short-Time Fourier transform (STFT) is a helpful tool to identify muscle fatigue with clinical and sports applications. However, the choice of STFT parameters may affect the estimation of myoelectrical manifestations of fatigue. Here, we determine the effect of window length and overlap selections on the frequency slope and the coefficient of variation from EMG spectrum features in fatiguing contractions. We also determine whether STFT parameters affect the relationship between frequency slopes and task failure. Eighty-eight healthy adult men performed one-leg heel-rise until exhaustion. A factorial design with a window length of 50, 100, 250, 500, and 1000 ms with 0, 25, 50, 75, and 90…

AdultMaleCoefficient of variation0206 medical engineeringBiomedical EngineeringBiophysics02 engineering and technologyElectromyography03 medical and health sciencessymbols.namesake0302 clinical medicineIsometric ContractionmedicineCluster AnalysisHumansOrthopedics and Sports MedicineMuscle SkeletalCluster analysisMathematicsFourier AnalysisMuscle fatiguemedicine.diagnostic_testElectromyographybusiness.industryDimensionality reductionRehabilitationShort-time Fourier transformPattern recognitionFunction (mathematics)020601 biomedical engineeringFourier transformMuscle FatiguesymbolsArtificial intelligencebusiness030217 neurology & neurosurgeryMuscle ContractionJournal of Biomechanics
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Inter-joint coordination of posture on a seesaw device

2016

Even though specific adjustments of the multi-joint control of posture have been observed when posture is challenged, multi-joint coordination on a seesaw device has never been accurately assessed. The current study was conducted in order to investigate the multi-joint coordination when subjects were standing on either a seesaw device or on a stable surface, with the eyes open or closed. Eighteen healthy active subjects were recruited. A principal component analysis and a Self-Organizing Maps analysis were performed on the joint angles in order to detect and characterize dominant coordination patterns. Intermuscular EMG coherence was analysed in order to assess the neurophysiological mechan…

AdultMaleComputer sciencePostureBiophysicsNeuroscience (miscellaneous)Postural control03 medical and health sciences0302 clinical medicineSeesaw molecular geometryControl theorymedicineHumansMuscle SkeletalPostural BalanceJoint (geology)Eyes openVision OcularPrincipal Component AnalysisProprioception030229 sport sciencesNeurophysiologymedicine.anatomical_structureFemaleNeurology (clinical)AnkleAnkleAnkle JointPsychomotor Performance030217 neurology & neurosurgeryCoherence (physics)Journal of Electromyography and Kinesiology
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Effects of grip and push forces on the acute response of the hand-arm system under vibrating conditions

1993

The purpose of the occupational medicine component of a joint research project was to study the effects of grip and push forces on the acute reaction of the hand-arm system under vibrating conditions. Several series of experiments were carried out by means of a vibration simulator in a laboratory environment in order to study biodynamic vibration behaviour, muscle response, skin temperature, shifts of the vibration perception threshold and the intensity of subjective vibration perception; in addition, field tests with hammer drills were conducted. On the whole, the findings obtained suggest that the coupling of the hand with the handle involved in using vibrating tools has a considerable im…

AdultMaleComputer sciencebusiness.industryMusclesMuscle responsePublic Health Environmental and Occupational HealthBiomechanicsStructural engineeringHandVibrationlaw.inventionJoint researchVibrationVibration perceptionlawArmHumansSkin circulationHammerbusinessHand armInternational Archives of Occupational and Environmental Health
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