Search results for "Musculoskeletal diseases."

showing 10 items of 842 documents

Chondrodysplasia punctata, tibia-metacarpal (MT) type.

1990

We describe 7 patients with a new form of chondrodysplasia punctata. Its principal clinical manifestations are flat midface and nose, short limbs, and otherwise normal development. Consistent radiologic manifestations in the newborn infant are discrete calcific stippling, coronal clefts of vertebral bodies, short tibiae, and shortness of the 2nd and 3rd metacarpal bones. Radiologic findings in the older child include shortness of tibiae and the 3rd and 4th metacarpals.

musculoskeletal diseasesMaleChondrodysplasia PunctataAdolescentLimb Deformities CongenitalMetacarpal bonesShort staturemedicineHumansChondrodysplasia punctataAbnormalities MultipleTibiaChildGenetics (clinical)NoseShort tibiaTibiabusiness.industryInfant NewbornInfantAnatomymusculoskeletal systemmedicine.diseaseOsteochondrodysplasiamedicine.anatomical_structureShort limbsChild PreschoolFaceFemalemedicine.symptomMetacarpusbusinessAmerican journal of medical genetics
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Stippled epiphyses in fetal alcohol syndrome.

1990

We report on punctate epiphyseal calcifications (stippled epiphyses) in the fetal alcohol syndrome and present the differential diagnosis of chondrodysplasia punctata. A literature survey shows that epiphyseal calcifications accompanying alcoholic embryopathy are regularly located in the lower limbs and rarely found in the upper extremities.

musculoskeletal diseasesMaleChondrodysplasia Punctatabusiness.industryFetal alcohol syndromeInfant NewbornCalcinosisStippled epiphysesAnatomymedicine.diseaseDiagnosis DifferentialRadiographyFetal Alcohol Spectrum DisordersPediatrics Perinatology and Child HealthmedicineHumansRadiology Nuclear Medicine and imagingChondrodysplasia punctataDifferential diagnosisLiterature surveybusinessPediatric radiology
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Case series of fluoroscopic findings and 3D reconstruction of human spinal MRIs of the space of Okada.

2020

Objective To better understand the unexpected spread of contrast medium observed by conventional fluoroscopic X-ray images during standard neuraxial techniques used in the treatment of pain. The support of 3D reconstruction of MRI images of structures within the lumbar spine was used to better understand the space of Okada. Methods Lumbar facet joint and epidural corticosteroid injections in five patients under fluoroscopic guidance with loss of resistance to air or saline to identify the facet joints or epidural space. Next, in a retrospective study, the authors examined the retrodural space of Okada and the neighboring tissues with 3D reconstruction of spinal MRIs of seven patients withou…

musculoskeletal diseasesMaleFacet (geometry)HistologyContrast MediaInjections EpiduralFacet joint03 medical and health sciences0302 clinical medicineImaging Three-DimensionalLumbar facet jointImage Interpretation Computer-AssistedmedicineHumansLoss of resistanceAgedRetrospective Studies0303 health sciencesLumbar Vertebraebusiness.industry3D reconstruction030206 dentistryGeneral MedicineAnatomyMiddle Agedmusculoskeletal systemMagnetic Resonance ImagingEpidural spaceContrast mediummedicine.anatomical_structure030301 anatomy & morphologyFluoroscopyLumbar spineFemaleAnatomybusinessExtravasation of Diagnostic and Therapeutic MaterialsClinical anatomy (New York, N.Y.)REFERENCES
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Effect of Laser Radiation on Infected Sites for the Immediate Placement of Dental Implants.

2020

Objective: The study aims to evaluate the feasibility of erbium-chromium: yttrium-scandium-gallium-garnet (ErCr:YSGG 2780 nm) laser irradiation on infected and/or inflamed post-extraction sites for...

musculoskeletal diseasesMaleImmediate Dental Implant LoadingBiomedical EngineeringDentistryLasers Solid-StateRadiationlaw.inventionLaser therapylawMedicineHumansSurgical Wound InfectionRadiology Nuclear Medicine and imagingIrradiationTooth Socketbusiness.industryMiddle AgedLaserDisinfectionDebridementBone SubstitutesTooth ExtractionFeasibility StudiesFemalebusinessPhotobiomodulation, photomedicine, and laser surgery
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Modulation of type II collagen-induced arthritis in DBA/1 mice by intravenous application of a peptide from the C1q-A chain.

1992

In this report we are able to show that intravenous (i.v.) application (day 0) of a nonapeptide (residues 26-34) from the human C1q A-chain (designated peptide A-C1q) prior to intradermal (i.d.) administration of chicken type II collagen (CII) in arthritis-susceptible DBA/1 mice (H2q), leads to abrogation of polymorphonuclear neutrophil (PMN) invasion into the joints. This nonapeptide exhibits epitope characteristics and high homology to residues 137-147 of CB11 (a cyanogen bromide fragment of chicken CII, known to contain both arthritis inducing and suppressing determinants). Arthritis index was lowest in animals pretreated i.v. with CII (as internal control), though animals pretreated i.v…

musculoskeletal diseasesMaleInjections IntradermalImmunologyMolecular Sequence DataType II collagenArthritischemical and pharmacologic phenomenaPeptideEpitopechemistry.chemical_compoundMiceAntigenAdjuvants ImmunologicmedicineImmunology and AllergyAnimalsAmino Acid Sequenceskin and connective tissue diseasesPeptide sequencechemistry.chemical_classificationbiologyArthritisComplement C1qHematologymedicine.diseaseMolecular biologyPeptide FragmentschemistryMice Inbred DBAImmunologyAntibody FormationInjections Intravenousbiology.proteinCyanogen bromideCollagenAntibodyOligopeptidesImmunobiology
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Evaluation of the osteoclastogenic process associated with RANK / RANK-L / OPG in odontogenic myxomas

2018

Background Odontogenic myxoma (OM) is a benign intraosseous neoplasm that exhibits local aggressiveness and high recurrence rates. Osteoclastogenesis is an important phenomenon in the tumor growth of maxillary neoplasms. RANK (Receptor Activator of Nuclear Factor κappa B) is the signaling receptor of RANK-L (Receptor activator of nuclear factor kappa-Β ligand) that activates the osteoclasts. OPG (osteoprotegerin) is a decoy receptor for RANK-L that inhibits pro-osteoclastogenesis. The RANK / RANKL / OPG system participates in the regulation of osteolytic activity under normal conditions, and its alteration has been associated with greater bone destruction, and also with tumor growth. Object…

musculoskeletal diseasesMaleOdontogenic myxomaRANK-LRANKOdontogenic myxoma03 medical and health sciences0302 clinical medicineOsteoprotegerinOsteoclastogenesis.MedicineNeoplasmHumansMIXOMAReceptorGeneral DentistryLanguageOSTEOGENESISDental follicleOral Medicine and PathologybiologyActivator (genetics)business.industryResearch030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseDental follicleLIGANDO RANKOtorhinolaryngologyRANKL030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCancer researchbiology.proteinImmunohistochemistryOPGSurgerybusinessMyxomaMedicina Oral, Patología Oral y Cirugía Bucal
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Patterns of trunk spine growth in two congeneric species of acanthocephalan: investment in attachment may differ between sexes and species.

2012

SUMMARYAcanthocephalans have evolved a hooked proboscis and some taxa have trunk spines to attach to their definitive hosts. These structures are generated before being used, thus a key question is how investment in attachment could optimally be allocated through the ontogeny. The number and arrangement of hooks and spines are never modified in the definitive host, but it is unclear whether these structures grow during adult development. A comparison of the size of trunk spines between cystacanths and adults of Corynosoma cetaceum and C. australe indicated that spines grow in both species, but only in females, which also had significantly larger spines than males. This sexual dimorphism did…

musculoskeletal diseasesMaleOntogenyDolphinsZoologyFlounderAcanthocephalaHost-Parasite InteractionsSpecies SpecificityAnimalsBody SizeSex CharacteristicsbiologyEcologyProboscismusculoskeletal systembiology.organism_classificationTrunkSpineSea LionsSexual dimorphismSpine (zoology)Infectious DiseasesPerchesKey (lock)Animal Science and ZoologyParasitologyFemaleAllometryHelminthiasis AnimalAcanthocephalaParasitology
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Cells of extramammary Paget's disease express cytokeratins different from those of epidermal cells.

1985

The patterns of expression of cytokeratin polypeptides which are closely correlated to routes of differentiation of epithelial cells were studied in extramammary Paget's disease. Cytokeratins of uninvolved and involved epidermis were analyzed by two-dimensional gel electrophoresis of microdissected tissue preparations as well as by immunofluorescence microscopy using cytokeratin antibodies with different specificities. In uninvolved epidermis, cytokeratins Nos. 1, 5, 6, 10, 11, 14, and 16, characteristic of keratinocytes, were found. Epidermis infiltrated by Paget's cells contained the same components and, in addition, cytokeratins Nos. 7, 8, 18, and 19, the latter being characteristic of s…

musculoskeletal diseasesMalePathologymedicine.medical_specialtySkin NeoplasmsDuctal cellsCellular differentiationFluorescent Antibody TechniqueDermatologyHistogenesisBiologyExtramammary Paget's diseaseBiochemistryCytokeratinotorhinolaryngologic diseasesmedicineHumansMolecular BiologyAgedSkinEpidermis (botany)Staining and LabelingApocrineCell Biologymedicine.diseasemedicine.anatomical_structurePaget Disease ExtramammaryKeratinsKeratinocytePeptidesImmunoelectrophoresis Two-DimensionalThe Journal of investigative dermatology
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Nonadherence in outpatient thrombosis prophylaxis with low molecular weight heparins after major orthopaedic surgery

2010

Background: According to some current guidelines, extended thromboprophylaxis after hip and knee arthroplasties is recommended. Outpatient prophylaxis with low molecular weight heparins (LMWH) is an important part of this prophylaxis, although the rates of adherence to these regimens is not known. Questions/purposes: We determined (1) the degree of nonadherence (NA) of patients with LMWH outpatient prophylaxis, and (2) whether specific independent factors explain NA. Methods: NA was determined by syringe count and by indirect and direct questions to patients. We defined six different NA indicators. To identify factors explaining LMWH NA, we used three different logistic regression models. R…

musculoskeletal diseasesMaleQuestionnairesmedicine.medical_specialtyHealth Knowledge Attitudes PracticeTime Factorsmedicine.drug_classmedicine.medical_treatmentArthroplasty Replacement HipLow molecular weight heparinRisk AssessmentInjectionsMedication AdherenceAmbulatory careFibrinolytic AgentsClinical ResearchRisk FactorsInternal medicineSurveys and QuestionnairesGermanyAmbulatory CareMedicineHumansOrthopedics and Sports Medicine/dk/atira/pure/core/keywords/559092180Arthroplasty Replacement KneeAgedbusiness.industryAnticoagulantHealth sciencesThrombosisGeneral MedicineHeparinHeparin Low-Molecular-Weightmedicine.diseaseThrombosisArthroplastySurgeryTelephoneLogistic ModelsTreatment OutcomeOrthopedic surgerySurgeryFemalebusinessFibrinolytic agentmedicine.drug
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Acute (0-2h) and delayed (2-8D) effects of exercise-induced muscle damage and soreness on elbow target movements.

2011

The aim was to examine the acute and delayed effects of exercise-induced muscle damage and soreness on elbow target movements (TM) performance and control. Ten males performed an exercise of 50 maximal eccentric elbow actions. TMs were performed at three movement ranges. Maximal forces, active stretch reflex and TM were tested, and muscle soreness, creatine kinase and elbow joint stiffness were determined acute (after and 2 h) and delayed (2, 4, 6, 8d) postexercise. Both the long lasting muscle soreness and force drop were observed after the exercise. Joint stiffness was increased at 2 h postexercise. The highest deterioration in flexion-TM performance was found at the time (2 h) and at the…

musculoskeletal diseasesMaleReflex Stretchmedicine.medical_specialtyElbowPainPhysical Therapy Sports Therapy and RehabilitationElectromyographyPhysiology (medical)Internal medicineIsometric ContractionmedicineElbowEccentricHumansStretch reflexExercise physiologyMuscle SkeletalCreatine KinaseExercisemedicine.diagnostic_testbusiness.industryElectromyographyMotor controlAnatomymusculoskeletal systembody regionsmedicine.anatomical_structureJoint stiffnessMuscle FatigueReflexCardiologyNeurology (clinical)medicine.symptombusinessElbow InjuriesMotor control
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