Search results for "N compounds"

showing 3 items of 203 documents

Newer formulations of intravenous iron: a review of their chemistry and key safety aspects - hypersensitivity, hypophosphatemia, and cardiovascular s…

2021

Introduction: The newest intravenous (IV) iron products show an improved safety profile over predecessors, allowing for the rapid administration of relatively high doses. Ferric derisomaltose (FDI; also known as iron isomaltoside), ferric carboxymaltose (FCM), and ferumoxytol (FER), are successful treatments for iron deficiency (Europe; FDI and FCM) and iron deficiency anemia (US; FDI, FCM, and FER).Areas covered: This review focusses on the chemistry and structure of FDI, FCM, and FER, and on three key aspects of IV iron safety: (1) hypersensitivity; (2) hypophosphatemia and sequelae; (3) cardiovascular safety.Expert opinion: Although the safety of modern IV iron has improved, immediate in…

medicine.medical_specialtySide effectAnemiaHypophosphatemia030204 cardiovascular system & hematologyDrug Hypersensitivity03 medical and health sciences0302 clinical medicinemedicineHumansPharmacology (medical)Intensive care medicineAnemia Iron-Deficiencybusiness.industryGeneral MedicineIron deficiencymedicine.diseaseFerumoxytolIron-deficiency anemiaCardiovascular Diseases030220 oncology & carcinogenesisFerricAdministration IntravenousbusinessAnaphylaxisHypophosphatemiaIron Compoundsmedicine.drugExpert opinion on drug safety
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Structure ofD-ribonic acid-dimethyltin(IV) in coordinating solvents: an experimental and DFT119Sn NMR study

2006

We have investigated a newly synthesized complex of D-ribonic acid with dimethyltin(IV). The structure of the complex in solution has been characterized by means of 1 H, 13 C, and 119 Sn NMR and by DFT calculations. The comparison of experimental and computational results allowed the determination of the stable conformation in solution as well as the detection of a dimerization process. Moreover, evidence is given of active coordination of the metal by the solvent.

organotin compounds; ribonic acid; carbohydrate-metal complexes; 119Sn NMR; DFT calculationsChemistryOrganic Chemistrycarbohydratestin compoundstin-119carbohydrates; tin compounds; tin-119; NMR spectroscopy; computational chemistrycomputational chemistryMetalSolventNMR spectroscopyComputational chemistryvisual_art119Sn NMR Carbohydrate-metal complexes DFT calculations Organotin compounds Ribonic acidvisual_art.visual_art_mediumOrganic chemistryPhysical and Theoretical ChemistryJournal of Physical Organic Chemistry
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The Nature of Transannular Interactions in E4N4 and E82+ (E = S, Se)

2012

The electronic structures of tetrachalcogen tetranitrides, E4N4, and octachalcogen dications, E82+, and the nature of their intramolecular E···E interactions (E = S, Se) was studied with high-level theoretical methods. The results reveal that the singlet ground states of both systems have a surprisingly large correlation contribution which functions to weaken and therefore lengthen the cross-ring E–E bond. The observed correlation effects are primarily static in E4N4, whereas in E82+ the dynamic part largely governs the total correlation contribution. The presented description of bonding is the first that gives an all-inclusive picture of the origin of cross-ring interactions in E4N4 and E8…

rikki-typpi -yhdisteetoctachalcogen dicationselectronic structurekalkogeenikationitsulfur-nitrogen compoundselektronirakenne
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