Search results for "N-2"
showing 10 items of 1881 documents
CCDC 1029116: Experimental Crystal Structure Determination
2015
Related Article: Alexander N. Chernyshev, Maria V. Chernysheva, Pipsa Hirva, Vadim Yu. Kukushkin, Matti Haukka|2015|Dalton Trans.|44|14523|doi:10.1039/C4DT03167A
CCDC 1029122: Experimental Crystal Structure Determination
2015
Related Article: Alexander N. Chernyshev, Maria V. Chernysheva, Pipsa Hirva, Vadim Yu. Kukushkin, Matti Haukka|2015|Dalton Trans.|44|14523|doi:10.1039/C4DT03167A
CCDC 1549500: Experimental Crystal Structure Determination
2017
Related Article: Brian M. Barry, R. Graeme Soper, Juha Hurmalainen, Akseli Mansikkamäki, Katherine N. Robertson, William L. McClennan, Alex J. Veinot, Tracey L. Roemmele, Ulrike Werner-Zwanziger, René T. Boeré, Heikki M. Tuononen, Jason A. C. Clyburne, Jason D. Masuda|2018|Angew.Chem.,Int.Ed.|57|749|doi:10.1002/anie.201711031
CCDC 871116: Experimental Crystal Structure Determination
2015
Related Article: Michael Mirion, Lars Andernach, Caroline Stobe, Joaquin Barjau, Dieter Schollmeyer, Till Opatz, Arne Lützen, Siegfried R. Waldvogel|2015|Eur.J.Org.Chem.|2015|4876|doi:10.1002/ejoc.201500600
Nenukleozīdu HIV – 1 reversās transkriptāzes inhibitoru sintēze
2016
Nenukleozīdu HIV – 1 reversās transkriptāzes inhibitoru sintēze. Pustenko A., zinātniskie vadītāji Dr. chem. Žalubovskis R, Dr. chem. Igors Kļimenkovs. Maģistra darbs 71 lappuses, 58 attēli, 20 tabulas, 33 literatūras avoti. Latviešu valodā. Darbā tika sintezēti 3,4-dihidropirimidīn-2(1H)-oni un to mono- N-1 un N-1, N-3 bisatvasinājumi reakcijās ar virkni sulfonilhlorīdu un acilhlorīdu. Sintezēto savienojumu struktūra apstiprināta ar KMR spektriem, kā arī ar Rentgenstruktūranalīzi. Literatūras apskatā apkopota informācija par 3,4-dihidropirimidīn-2(1H)-onu sintēzes metodēm, to acilēšanu un sulfonilēšanu.
CCDC 891057: Experimental Crystal Structure Determination
2012
Related Article: G.Bentabed-Ababsa, S.Hamza-Reguig, A.Derdour, L.R.Domingo, J.A.Saez, T.Roisnel, V.Dorcet, E.Nassar, F.Mongin|2012|Org.Biomol.Chem.|10|8434|doi:10.1039/c2ob26442k
CCDC 1862873: Experimental Crystal Structure Determination
2018
Related Article: A. Zagidullin, D. Islamov, E. Oshchepkova, P. Lonnecke, V. Miluykov|2018|Acta Crystallogr.,Sect.E:Cryst.Commun.|74|1336|doi:10.1107/S2056989018011775
Diastereoselective synthesis of 6-functionalized 4-aryl-1,3-oxazinan-2-ones and their application in the synthesis of 3-aryl-1,3-aminoalcohols and 6-…
2010
Abstract Halocyclocarbamation of benzyl N -(1-phenyl-3-butenyl)carbamates afforded 6-functionalized 4-aryl-1,3-oxazinan-2-ones with moderate to excellent diastereoselectivity depending on the N -substituent. Importantly, in contrast to reported cyclocarbamations of homoallylic carbamates, which are generally trans -diastereoselective, cyclization of N -unsubstituted Cbz-protected homoallylamines led to cis -1,3-oxazinan-2-ones, predominantly. The use of N -benzylated and in situ prepared N -silylated derivatives resulted however in trans -selectivity. Transition states are proposed to explain the stereochemical influence of the N -substituent on the cyclocarbamations. The functionalized 1,3…
CCDC 1040500: Experimental Crystal Structure Determination
2015
Related Article: Zsolt Szakonyi, Árpád Csőr, Matti Haukka, Ferenc Fülöp|2015|Tetrahedron|71|4846|doi:10.1016/j.tet.2015.05.019
Nanoparticles of a polyaspartamide-based brush copolymer for modified release of sorafenib: In vitro and in vivo evaluation.
2017
Abstract In this paper, we describe the preparation of polymeric nanoparticles (NPs) loaded with sorafenib for the treatment of hepatocellular carcinoma (HCC). A synthetic brush copolymer, named PHEA-BIB-ButMA (PBB), was synthesized by Atom Trasnfer Radical Polymerization (ATRP) starting from the α-poly( N -2-hydroxyethyl)- d , l -aspartamide (PHEA) and poly butyl methacrylate (ButMA). Empty and sorafenib loaded PBB NPs were, then, produced by using a dialysis method and showed spherical morphology, colloidal size, negative ζ potential and the ability to allow a sustained sorafenib release in physiological environment. Sorafenib loaded PBB NPs were tested in vitro on HCC cells in order to e…