Search results for "N3"

showing 10 items of 153 documents

Cholesterol-Inulin Conjugates for Efficient SN38 Nuclear Delivery: Nanomedicines for Precision Cancer Therapy

2022

An amphiphilic inulin-thiocholesterol conjugate (INU-Cys-TC) was strategically designed as a biodegradable core-shell nanocarrier of 7-ethyl-10-hydroxy-camptothecin (SN38) to enhance its solubility and stability in aqueous media, thus exploiting its brilliant anticancer effect. INU-Cys-TC was designed to have the hydrophilic inulin backbone (external shell) partially functionalized with hydrophobic thiocholesterol moieties (internal core) through a biodegradable disulfide bond due to cysteamine bridges. Thiocholesterol moieties impair redox-sensitive self-assembling abilities, yielding to nano-sized micelles in aqueous media capable of efficiently encapsulating a high amount of SN38 (DL = 8…

SN38Cancer ResearchinulinOncologytriple negative breast cancerdrug deliverycolorectal cancerpolymeric micellesinulin; SN38; drug delivery; polymeric micelles; colorectal cancer; triple negative breast cancerCancers; Volume 14; Issue 19; Pages: 4857
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3D structural modeling and restoration of the Apennine-Maghrebian chain in Sicily: Application for non-cylindrical fold-and-thrust belts

2019

International audience; Thirteen seismic reflection profiles and field observations have been used to build a three-dimensional watertight geological model of the sub-surface architecture of the Trapanese carbonate platform unit of the Apennine-Maghrebian chain in the Mt. Kumeta and Mt. Rocca Busambra (NW Sicily, Italy). Either a single step or a two-step thrust-fault deformation model is acceptable on the basis of seismic interpretation but the integration of 3D model reconstruction and 3D geomechanical restoration, validates only the scenario with a single stage of deformation.The 3D model highlights along strike variations of the structural style for the Trapanese unit where pre-existing…

Seismic interpretation3D geological modeling3D restorationCarbonate platform unitSicilian fold-and-thrust beltApennine-Maghrebian chain010504 meteorology & atmospheric sciencesApennine-Maghrebian chainCarbonate platform3D geological modeling[SDU.STU]Sciences of the Universe [physics]/Earth Sciences3d modelSingle stepThrustClassification of discontinuities010502 geochemistry & geophysics01 natural sciencesseismic interpretationSicilian fold-and-thrust beltseismic interpretation; 3D geological modeling; 3D restoration; carbonate platform unit; Sicilian fold-and-thrust belt; Apennine-Maghrebian chainMesozoicPetrologyGeophysic0105 earth and related environmental sciencesEarth-Surface ProcessesFold (geology)Geophysicscarbonate platform unitSeismic interpretation3D restorationGeologyTectonophysics
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Loss of the Sin3A/Rpd3 Histone De-Acetylase Complex Causes Telomeric Fusions

2008

Sin3A RPD3 HDAC
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CCDC 2070865: Experimental Crystal Structure Determination

2021

Related Article: Oleh Stetsiuk, Abdelkrim El-Ghayoury, Francesc Lloret, Miguel Julve, Narcis Avarvari|2021|Molecules|26|2122|doi:10.3390/molecules26082122

Space GroupCrystallography(mu-N3N6-bis[(pyridin-2-yl)methyl]-1245-tetrazine-36-diamine)-tetrakis(111555-hexafluoroacetylacetonato)-di-nickel acetonitrile solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1985134: Experimental Crystal Structure Determination

2020

Related Article: Adrien T. Normand, E. Daiann Sosa Carrizo, Corentin Magnoux, Esteban Lobato, Hélène Cattey, Philippe Richard, Stéphane Brandès, Charles H. Devillers, Anthony Romieu, Pierre Le Gendre, Paul Fleurat-Lessard|2021|Chemical Science|12|253|doi:10.1039/D0SC04736H

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(N1N3-diphenyl-1133-tetra(propan-2-yl)-3-triphosph-2-en-1-ium-13-bis(aminide))-tetrahydrofuran-lithiumExperimental 3D Coordinates
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CCDC 271503: Experimental Crystal Structure Determination

2006

Related Article: T.Gans-Eichler, D.Gudat, K.Nattinen, M.Nieger|2006|Chem.-Eur.J.|12|1162|doi:10.1002/chem.200500576

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(N2N3-bis(246-trimethylphenyl)but-2-ene-23-bis(aminido))-germanium(ii)Experimental 3D Coordinates
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CCDC 2070864: Experimental Crystal Structure Determination

2021

Related Article: Oleh Stetsiuk, Abdelkrim El-Ghayoury, Francesc Lloret, Miguel Julve, Narcis Avarvari|2021|Molecules|26|2122|doi:10.3390/molecules26082122

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(mu-N3N6-bis[(pyridin-2-yl)methyl]-1245-tetrazine-36-diamine)-tetrakis(111555-hexafluoroacetylacetonato)-di-copper(ii) methanol solvateExperimental 3D Coordinates
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CCDC 1985138: Experimental Crystal Structure Determination

2020

Related Article: Adrien T. Normand, E. Daiann Sosa Carrizo, Corentin Magnoux, Esteban Lobato, Hélène Cattey, Philippe Richard, Stéphane Brandès, Charles H. Devillers, Anthony Romieu, Pierre Le Gendre, Paul Fleurat-Lessard|2021|Chemical Science|12|253|doi:10.1039/D0SC04736H

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(t-butylimino)-(chloro)-[N1N31133-hexaphenyl-13-triphosphane-13-diaminato]-(pyridine)-titanium(iv) unknown solvateExperimental 3D Coordinates
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CCDC 1985137: Experimental Crystal Structure Determination

2020

Related Article: Adrien T. Normand, E. Daiann Sosa Carrizo, Corentin Magnoux, Esteban Lobato, Hélène Cattey, Philippe Richard, Stéphane Brandès, Charles H. Devillers, Anthony Romieu, Pierre Le Gendre, Paul Fleurat-Lessard|2021|Chemical Science|12|253|doi:10.1039/D0SC04736H

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(t-butylimino)-(chloro)-[N1N31133-hexaphenyl-13-triphosphane-13-diaminato]-(pyridine)-titanium(iv) unknown solvateExperimental 3D Coordinates
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CCDC 2118012: Experimental Crystal Structure Determination

2022

Related Article: Joschua Helmer, Olli J. Pakkanen, Chris Gendy, Alexander Hepp, Heikki M. Tuononen, Felicitas Lips|2022|Chem.Commun.|58|3549|doi:10.1039/D2CC00298A

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters1-bromo-N1N2N3-tris[26-bis(propan-2-yl)phenyl]-N1N2N3-tris(trimethylsilyl)-1H-trisilirene-123-triamineExperimental 3D Coordinates
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