Search results for "NAD"
showing 10 items of 2033 documents
Mechanisms of Increased Vascular Superoxide Production in an Experimental Model of Idiopathic Dilated Cardiomyopathy
2005
Objective— In the present study, we sought to identify mechanisms underlying increased oxidative stress in vascular tissue in an experimental animal model of chronic congestive heart failure (CHF). Methods and Results— Superoxide and nitric oxide (NO) was measured in vessels from cardiomyopathic hamsters (CHF hamsters) and golden Syrian hamsters. We also determined expression of endothelial nitric oxide synthase (NOSIII), the soluble guanylyl cyclase, the cGMP-dependent kinase, and the NADPH oxidase. To analyze the contribution of the renin-angiotensin system to oxidative stress, CHF hamsters were treated with the angiotensin-converting enzyme inhibitor captopril for 200 days (120 mg · kg …
Un hombre al servicio del rey: Francisco de Lemos, conde de Castro (1601-1620)
2010
Las peculiaridades de la corte de Felipe III permitieron a algunos representantes de la alta aristocracia ligados al duque de Lerma, por parentesco o amistad, incrementar su poder y su peso político. Entre éstos, los Lemos tuvieron un papel de primer orden, especialmente en lo relativo a las cortes periféricas de la Península Italiana. En este trabajo se analizan algunos aspectos de la carrera politica de Francisco Lemos, VIII conde de Castro que entre 1601 y 1621 estuvo en los lugares clave para el equilibrio de la política internacional: Nápoles, Venecia, Roma, Sicilia.
La memoria traumática en Carmen Laforet: la mujer como testigo del conflicto
2020
El trabajo se centra en algunos personajes femeninos de la novelística de Carmen Laforet, en su relación con el conflicto español de 1936. Como es notorio, la guerra civil no representa un tema dominante de la narrativa de la autora, pero eso no impide que muchos de sus personajes manifiesten un reflejo tangible del conflicto recién terminado. En especial, se señala el trauma del conflicto como un motivo latente de cada obra de Laforet, en relación a las evidentes consecuencias psicofísicas que afectan a sus personajes. Partiendo de Nada (1945), cuya relación con la guerra ya ha sido señalada por parte de la crítica, hasta la trilogía de “Tres pasos fuera del tiempo”(1963- 2004), el conjunt…
Villancicos, que se han de cantar en los solemnes Maytines del Nacimiento de N. Señor Jesu Christo, en la Santa Iglesia Metropolitana de Valencia, en…
Grav. xil. de la Mare de Déu de la Seu amb el Jesuset Totes les p. orlades Sign.: [ ]4 Text a línia tirada i a dues col. separades per filet
Letras de los Villancicos, que se han de cantar en los solemnes Maytines del Nacimiento de N. Señoror Jesu-Christo, en la Santa Iglesia Metropolitana…
Només el text, sense la música Grav. xil. amb l'anagrama de la Verge Maria a la port Filets Text a 1 i a 2 col. - Reclams
Villancicos para la Natividad del Señor en la Santa Metropolitana Iglesia de Valencia en este año M.DCCC.IX.
Només el text, sense la música Grav. xil. a la port. amb l'anagrama de Maria Sign.: [ ]4 Text a dues col. i a línia tirada
Letras de los villancicos, que se han de cantar en los solemnes Maytines del Sagrado Nacimiento de nuestro Redemptor Jesu Christo en la Santa Iglesia…
Sig. A4 Totes les p. orlades. - Text a dues col. i línia tirada. - Reclams
Susceptibility of Pseudomonas aeruginosa isolates to ceftazidime is unrelated to the expression of the outer membrane protein OprC.
1997
Previously, it has been postulated that the porin OprC facilitates the diffusion of ceftazidime through the outer membrane of Pseudomonas aeruginosa. To further investigate this claim, the outer membrane protein (OMP) profiles of 22 ceftazidime-susceptible clinical isolates were analyzed. No correlation was found between MIC values and the level of expression of OprC. Further, OprC was either undetectable or expressed in reduced amounts in 12 isolates. In contrast, OprF and OprE were present in all isolates studied. This study suggests that OprC is dispensable for the permeation of ceftazidime through the outer membrane of P. aeruginosa.
Gender differences in the immune system activities of sea urchin Paracentrotus lividus
2013
In the immune system of vertebrates, gender-specific differences in individual immune competence are well known. In general, females possess more powerful immune response than males. In invertebrates, the situation is much less clear. For this purpose we have chosen to study the immune response of the two sexes of the echinoderm Paracentrotus lividus in pre- and post-spawning phases. The coelomic fluid from the echinoderms contains several coelomocyte types and molecules involved in innate immune defenses. In this article we report that the degree of immune responses in the P. lividus differs according to sex in both pre- and post-spawning phases. We found in all tests that females were mor…
Indicaxanthin inhibits NADPH oxidase (NOX)-1 activation and NF-κB-dependent release of inflammatory mediators and prevents the increase of epithelial…
2014
Dietary redox-active/antioxidant phytochemicals may help control or mitigate the inflammatory response in chronic inflammatory bowel disease (IBD). In the present study, the anti-inflammatory activity of indicaxanthin (Ind), a pigment from the edible fruit of cactus pear (Opuntia ficus-indica, L.), was shown in an IBD model consisting of a human intestinal epithelial cell line (Caco-2 cells) stimulated by IL-1β, a cytokine known to play a major role in the initiation and amplification of inflammatory activity in IBD. The exposure of Caco-2 cells to IL-1β brought about the activation of NADPH oxidase (NOX-1) and the generation of reactive oxygen species (ROS) to activate intracellular signal…