Search results for "NAD"
showing 10 items of 2033 documents
Perceived Parental and Peer Support in Relation to Canadian, Cuban, and Spanish Adolescents’ Valuing of Academics and Intrinsic Academic Motivation
2011
The aim of this study was to explore possible parent and peer influences on adolescents’ valuing of academics and intrinsic academic motivation in cultures varying in traditional emphasis on the family unit (Cuba, Canada, and Spain). Perceived parent and peer support, parents’ expectations, and valuing of academics significantly predicted adolescents’ valuing of education and motivation. Spanish adolescents were less motivated than members of the other ethnic groups. The Spanish participants also reported lower perceived parental expectations than Chinese Canadians and less perceived peer support than did Cubans and Chinese Canadians. Perceived social support from same- and opposite-sex fr…
Decolonizing Othello in search of black feminist North American identities: Djanet Sears' Harlem duet and Toni Morrison's Desdemona
2017
<p>The plays <em>Harlem duet </em>(1997) by African Canadian playwright Djanet Sears and <em>Desdemona </em>(2012) by Toni Morrison signify upon European texts aiming to carve out a new definition of what it means to be black in North America. Therefore both texts make for interesting reading in the study of (black) identity construction within US and Canadian contexts for, by revising Shakespeare’s <em>Othello</em>, they rethink and rewrite a social and racial reality unrelentingly disrupted by difference and hybridity. Sears’ play establishes a specific reading of Canadianness in dialogue with African America to erect a possibility of healing and …
Phytotoponymy and Synphytotoponymy in Western Granada Province (Andalusia, Spain)
2009
En el marco de la investigación etnobotánica desarrollada en el poniente granadino, se ha realizado un estudio sobre la toponimia de la comarca con atención a los apelativos de origen vegetal (fitotopónimos y sinfitotopónimos). La información —obtenida de la Gerencia Territorial del Catastro de Granada, de la Junta de Andalucía y de nuestro trabajo de campo— se ha incluido en una base de datos con el programa Microsoft Excell®. Un total de 98 especies vegetales se encuentran representadas en la toponimia local, dando nombre a 593 lugares del territorio. Se aportan comentarios sobre el significado ecológico, paleofitogeográfico y etnobotánico de las especies reflejadas en la toponimia.
The Effect of Vanadium on the Content of Chlorophyll, P-700 and Cytochrome f at Different Light Intensities in Chlorella fusca
1980
Summary Cells of Chlorella fusca, were grown in liquid medium supplemented ,vith O.2% glucose and varied concentrations of vanadium both at 5 different light intensities and in the dark. \Vith increasing concentrations of vanadium the content of chlorophyll, P-700 and cytochrome f increased as well, each, however, in a different way. At the saturating concentration of 20 µg vanadium per litre the pigment content per dry weight was double as high as that of the vanadium-free control; the ratio of chlorophyll a/chlorophyll b increased from 2.1 to 2.9. The content of P-700 at saturating vanadium concentration was four times higher than that of the control when based on dry weight and double as…
Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme.
2019
Phosphorylation by kinases enzymes is a widespread regulatory mechanism able of rapidly altering the function of target proteins. Among these are cytochrome P450s (CYP450), a superfamily of enzymes performing the oxidation of endogenous and exogenous substrates thanks to the electron supply of a redox partner. In spite of its pivotal role, the molecular mechanism by which phosphorylation modulates CYP450s metabolism remains elusive. Here by performing microsecond-long all-atom molecular dynamics simulations, we disclose how phosphorylation regulates estrogen biosynthesis, catalyzed by the Human Aromatase (HA) enzyme. Namely, we unprecedentedly propose that HA phosphorylation at Y361 markedl…
NADPH-cytochrome P-450 reductase: Preferential inhibition by ellipticine and other type II compounds having little effect on NADPH-cytochrome c reduc…
1980
Abstract Ellipticine (5,11-dimethyl-[6H]-pyrido[4,3b]carbazole) binds with an affinity greater than most other compounds known to interact with P-450. Control and 3-methylcholanthrene-induced aryl hydrocarbon (benzo[ a ]pyrene) hydroxylase (EC 1.14.14.2) and acetanilide 4-hydroxylase and control and phenobarbital-induced ethylmorphine N -demethylase activities are all markedly inhibited by ellipticine to about the same extent. Ellipticine and other Type II compounds (metyrapone, octylamine-1, pyridine and aniline) preferentially inhibit NADPH-cytochrome P-450 reductase activity, while affecting NADPH-cytochrome c reductase activity very little. Butanol-1, a compound having pure Reverse Type…
All-Atom simulations disclose how cytochrome reductase reshapes the substrate access/egress routes of its partner cyp450s
2020
Cytochromes P450 enzymes (CYP450s) promote the oxidative metabolism of a variety of substrates via the electrons supplied by the cytochrome P450 reductase (CPR) and upon formation of a CPR/CYP450 adduct. In spite of the pivotal regulatory importance of this process, the impact of CPR binding on the functional properties of its partner CYP450 remains elusive. By performing multiple microsecond-long all-Atom molecular dynamics simulations of a 520â »000-Atom model of a CPR/CYP450 adduct embedded in a membrane mimic, we disclose the molecular terms for their interactions, considering the aromatase (HA) enzyme as a proxy of the CYP450 family. Our study strikingly unveils that CPR binding alters…
Ferric-reductase activities in Vibrio vulnificus biotypes 1 and 2.
1999
In this paper, the ferric-reductase activities of Vibrio vulnificus were investigated. This species comprises two biotypes pathogenic for humans and eels that are able to express different mechanisms for iron acquisition. All strains of both biotypes used in this study were able to reduce ferric citrate, irrespective of the iron levels in the growth medium. Some variation in the degree of reduction was observed among the strains, with the highest values corresponding to one acapsulated environmental strain of biotype 1. When cell fractions were tested, only those from periplasm and cytoplasm showed reductase activity whereas no activity was detected in membranes. Low temperatures inhibited …
Miniaturas de un manuscrito de la Batalla de Kulikovo (Rusia)
2005
El segundo cuarto del siglo XIII marcó un hito trágico en la historia de Rusia con la invasión mongola. Los éxitos militares de estas hordas asiáticas aterrorizaron a toda Europa. Los mongoles conquistaron el sur de Siberia, China, Turquestán, Afganistán y Persia, se extendieron por el Cáucaso y Transcaucasia, conquistaron Vladimir, Moscú y Kiev, devastaron Polonia, Silesia, Moravia y Hungría y aparecieron en 1241 ante las puertas de Viena. La invasión mongola se vio en Rusia como una catástrofe cósmica, una incursión de fuerzas sobrenaturales, algo inaudito e incomprensible. La batalla del campo de Kulikovo fue una de las más sangrientas de la historia rusa. Tuvo lugar el 8 de septiembre d…
El poder religiós: llibres il·luminats per als bisbes catalans baixmedievals (segles XIV-XV)
2011
En los inicios del Gótico Internacional, destaca en Cataluña la presencia de elevadas dignidades eclesiásticas, sensibles a las novedades artísticas procedentes de más allá de los Pirineos, que intervinieron en la petición de manuscritos de lujo. Una de las personalidades más atractivas fue Joan Ermengol, obispo de Barcelona, anterior abad del monasterio de Sant Cugat del Vallés, uno de los scriptoria más importantes en la elaboración de libros iluminados en torno al año 1400. En este contexto, destaca la representación de estos prelados en los manuscritos encargados bajo sus designios, generando un repertorio de imágenes que establece contactos con las aportaciones iconográficas potenciada…