Search results for "NEC"
showing 10 items of 9363 documents
Cell-cycle control in cell-biomaterial interactions
2000
Current biocompatibility testing involves the demonstration of cell proliferation, which is usually interpreted as a sign of positive biocompatibility when the materials sustain cell proliferation. As the field of biomaterials research is rapidly moving toward tissue-engineered devices and hybrid organs, control of cell function has become a main topic. Cell function, which involves specific differentiation pathways, cannot be separated from cell-cycle control. The study of cell-cycle control is an important extension of routine proliferation assays and has extensive roots in developmental and tumor biology. We studied the expression of the tumour suppressor gene p53 and the proliferation-a…
Estudio del efecto del paclitaxel en las propiedades físicas, biomecánicas y fisiológicas del tejido cutáneo en pacientes oncológicos y en cultivos d…
2020
La toxicidad en la piel es uno de los efectos perjudiciales más comunes de los taxanos. El objetivo fue evaluar el efecto del fármaco paclitaxel sobre la piel en un grupo de pacientes con cáncer ginecológico, y en un modelo 3D in vitro de piel, así como en melanocitos, queratinocitos, fibroblastos y en células microvasculares dérmicas humanas. En el estudio in vivo se realizaron las medidas en una población control de mujeres sanas (n=20) y una población de pacientes con tumores ginecológicos en tratamiento con paclitaxel (n=20), antes, durante y después. Las diferentes determinaciones fueron el valor de hidratación, la TEWL, el valor de sebo, valores de pigmentación y eritema, valores de e…
Oral paracoccidioidomycosis:a retrospective study of 95 cases from a single center and literature review
2023
The ecoepidemiological panorama of paracoccidioidomycosis (PCM) is dynamic and still ongoing in Brazil. In particular, data about the oral lesions of PCM are barely explored. The aim of this study was to report the clinicopathological features of individuals diagnosed with oral PCM lesions at an oral and maxillofacial pathology service in Rio de Janeiro, Brazil, in the light of a literature review. A retrospective study was conducted on oral biopsies obtained from 1958 to 2021. Additionally, electronic searches were conducted in PubMed, Embase, Scopus, Web of Science, Latin American and Caribbean Center on Health Sciences Information, and Brazilian Library of Dentistry to gather information…
Effetti del Papillomavirus genitale sulla riproduzione umana
2009
Human papillomaviruses (HPVs) are agents of the most common sexually transmitted disease that can infect both females and males. More than 100 HPV-genotypes are known, of these, 40 genotypes infect the low genital tract. Based on their association with cervical cancer and precursor lesions, genital HPVs can also be grouped to high-risk and low-risk HPV-types. Diagnosis of HPV infection is sometime difficult because the infection is often transient and asymptomatic. High-risk HPV types are more likely to persist than are low-risk HPV types. It’s the inability of the immune system to spontaneously clear HPV that leads to development of precancerous cervical lesions. It is generally assumed th…
More Time Children Spend in Nature During Preschool Is Associated with a Greater Sense of Responsibility for Nature : A Study in Finland
2021
Nature connectedness is an important factor underlying proenvironmental behavior. Only little is known on the aspects that influence nature connectedness in younger children. The study participants included 150 children at mean age of 6.5 years. Eighty-five of them attended nature-preschool that offers on average 13.1 h/week, and 65 of them typical preschool that offers on average 1.7 h/week, of their education in nature. Nature connectedness was measured with the connection to nature index. The regular visits to nature during preschool were associated with a higher sense of responsibility for nature (p = 0.013). The regular visits to nature during preschool, sex, parent's nature connectedn…
Cell Mediated Immune System Hyperactivation and Complications in Surgery. Is There a Correlation?
2010
Introduction: The role of the immune system in wound healing is multifaceted and cell-to-cell interactions may affect healing in several ways, many of which are probably still unknown. The case of a 19-year-old girl who, after multiple postsurgical complications, was found to have a transient immune system hyperactivation is reported. Materials and Methods: A 19-years-old woman with a breast asymmetry, previously treated with breast augmentation and contralateral reduction mammaplasty, had her implant removed and she came to our attention seeking autologous reconstruction. A free DIEP flap was performed and, again, wound breakdown and liponecrosis ensued at both the donor and recipient site…
Party autonomy regarding jurisdiction under the property regimes regulations
2021
The main accomplishment of the Property Regimes Regulations lies in their bringing more coherence into the cross-border family law adjudication. In the field of international jurisdiction, they strive to align the competence in couples? patrimony disputes to that in succession and in separation proceedings, or else to align the competence of the courts to the applicable law. These tendencies are clearly visible in the Regulations? provisions on choice of court agreements. Namely, the Regulations allow for such agreements, but severely limit parties? choice and the possible effects of these clauses. When succession or separation proceedings are pending, it is often only possible to institute…
PREVALENZA DELLE CO-MORBIDITA’ CARDIOMETABOLICHE IN SOGGETTI CON IPOADIPONECTINEMIA.
2014
Learning games and children's user experience : the effects of context
2015
Tutkimuksen tarkoituksena oli tutkia, onko lasten käyttäjäkokemuksissa eroja heidän pelatessa digitaalista peliä kahdessa eri kontekstissa. Käyttäjäkokemuk-sia selvitettiin myös tarkastelemalla pelaajien flow kokemuksia. Tutkimuksessa käytettiin MinecraftEdu peliä, joka on TeacherGaming LLC yrityksen tekemä vi-rallinen opetusversio Minecraft pelistä. Pelaamisen kontekstit, jossa peliä pelat-tiin, olivat kouluaika ja vapaa-aika. Erilaisista konteksteista johtuen sekä ulkoiset tekijät että myös sisäiset tekijät kuten, päämäärät, tavoitteet, ja motivaatio vaihtelevat. Tutkimuksessa käytetyt metodit koostuivat ääneen ajattelun, obser-voinnin ja kyselyjen yhdistelmistä. Kontekstilla näytti oleva…
Study of Zumba game playing experience, related to previous knowledge of Zumba
2014
The focus of this research is to make an analysis of the experiences of Xbox Kinect Zumba game players in correlation to the real Zumba classes. Through the observation of the Zumba game, specifically using the Xbox Kinect motion detection technology, the researcher intends to create a user experience similar to the real classroom experience and/or create a situation pleasant enough to interest the subjects in real Zumba classes or further game playing, despite of their preconceptions about the game/activity. Negative results will be used to pinpoint what is lacking in this situation and environment to achieve the level of comfort and enjoyment required. The researcher intends to show that …