Search results for "NEO"
showing 10 items of 41983 documents
Could PD-1/PDL1 immune checkpoints be linked to HLA signature?
2019
The outstanding clinical expansion of monoclonal antibodies (mAbs) to programmed cell death receptor-1 (PD-1) (nivolumab and pembrolizumab) and PD-1 ligand-1 (PDL-1) (atezolizumab, avelumab and durvalumab) has received an increasing level of interest regarding immunotherapy and multidrug combinations, for the treatment of a number of common human malignancies. Some patients treated with these agents receive remarkable benefits in term of quality of life, progression-free (PFS) and overall survival (OS). However, a significant percentage of these patients experience immune-related adverse events (irAEs), while others present with an ultra-rapid disease progression, defined as hyperprogressio…
Noninvasive neurostimulation methods for migraine therapy: The available evidence.
2016
Background Migraine is one of the most disabling neurological disorders. The current pharmacological armamentarium is not satisfying for a large proportion of patients because the responder rate does not exceed 50% on average and the most effective drugs often induce intolerable side effects. During recent years, noninvasive central and peripheral neuromodulation methods have been explored for migraine treatment. Overview A review of the available evidence suggests that noninvasive neuromodulation techniques could be beneficial for migraine patients. The transcranial stimulation methods allow modulating selectively cortical activity and can thus be curtailed to the patient’s pathophysiologi…
Analyse multicritère des valeurs et des vulnérabilités des espaces du Territoire de Belfort
2011
National audience
Les conflits de valeurs dans le champ du soin
2016
International audience
On Line Validation Exercise (OLIVE): A Web Based Service for the Validation of Medium Resolution Land Products. Application to FAPAR Products
2014
International audience; The OLIVE (On Line Interactive Validation Exercise) platform is dedicated to the validation of global biophysical products such as LAI (Leaf Area Index) and FAPAR (Fraction of Absorbed Photosynthetically Active Radiation). It was developed under the framework of the CEOS (Committee on Earth Observation Satellites) Land Product Validation (LPV) sub-group. OLIVE has three main objectives: (i) to provide a consistent and centralized information on the definition of the biophysical variables, as well as a description of the main available products and their performances (ii) to provide transparency and traceability by an online validation procedure compliant with the CEO…
Students’ Perceptions of Instructional Rubrics in Neurological Physical Therapy and Their Effects on Students’ Engagement and Course Satisfaction
2021
One of the main challenges faced by physical therapy (PT) students is to learn the practical skills involved in neurological physical therapy (PT). To help them to acquire these skills, a set of rubrics were designed for formative purposes. This paper presents the process followed in the creation of these rubrics and their application in the classroom, noting that students perceived them as valid, reliable, and highly useful for learning. The perception of the validity and usefulness of the rubrics has different closely related dimensions, showing homogeneous values across the students´ sociodemographic and educational variables, with the exception of dedication to studying, which showed a …
La validité des conventions de concubinage : observations sous Cass. 1ère civ., 20 juin 2006
2006
International audience
Creating Implicit Measure Stimulus Sets Using a Multi-Step Piloting Method
2023
The effect of arbitrary stimulus selection is a persistent concern when employing implicit measures. The current study tests a data-driven multi-step procedure to create stimulus items using a combination of free-recall and survey data. Six sets of stimulus items were created, representing healthy food and high sugar items in children, adolescents, and adults. Selected items were highly representative of the target concepts, in frequent use, and of near equal length. Tests of the piloted items in two samples showed slightly higher implicit measure–behavior relations compared to a previously used measure, providing preliminary support for the value in empirically based stimulus selection. Fu…
Minières, "ateliers" et hypogées. Étude de l’organisation du territoire dans les marais de Saint-Gond (Marne)
2013
National audience
La pedagogía vital de Séneca : enseñanza para vivir moralmente y comportarse cívicamente
2013
La pedagogía elaborada por Séneca tiene por objetivo la formación vital del ser humano. En el presente artículo se analizan principalmente sus cartas ¿pero también sus diálogos y tragedias¿ para determinar cuáles son los principios rectores del pensamiento pedagógico del estoico romano. Se trata de sintetizar cuáles son los principios morales exigibles a toda persona que pretenda asumir sus responsabilidades ciudadanas. Esta asunción no es opción, sino obligación vital para todo ser humano que pretenda alcanzar la madurez humana de vivir moralmente. La moral es la condición de la felicidad y, al tiempo, el rasgo distintivo del sabio. Estos tres conceptos son los que vertebran la pedagogía d…