Search results for "NEP"

Impact Acceleration During Prolonged Running While Wearing Conventional Versus Minimalist Shoes.

2020

Purpose: In recent years a sub-group of minimalist runners have emerged who aim to perform physical exercise more naturally in an attempt to reduce running-related injuries. Here we aimed to determine the effect that running with minimalist footwear in a prolonged run has on footimpact accelerations. Method: Seventeen runners ran with minimalist and conventional shoes (MS and CS, respectively) in two separate sessions; the participants had experience with both footwear types. We measured the length and frequency of each stride, as well as the tibial and head impact acceleration every 5 minutes during a prolonged run (30 minutes at 80% of each individual's maximum aerobic speed). Results: Th…

Impact of Foreign Aid on Economic Growth in Nepal

2019

Master's thesis Business Administration BE501 - University of Agder 2019 Nepal, being one of the least developed countries,has beenreceiving aid for more than six decades. It is very important to see how the country is being able to utilize the aid receipts in the economic developmentof the nation.Using annual time series data from 1983 to 2013, the effect of foreign aid oneconomic growth of Nepal has been analysed.The empirical work has beenperformed in two phases(1983-2002 and 1983-2013). The result from Johansen’s cointegrationtest for the shorter time interval, when there was relatively a poor economic situationin the country,revealsthat aid has a negative long-run effect on per capita …

Murdered women’s children: A social emergency and gloomy reality

2018

Femicide, defined as the killing of females by males because they are females, is be-coming recognized worldwide as an im-portant ongoing manifestation of gender inequality. Actual or imminent separation, abuser’s access to firearms, prior threats with a weapon, prior threats to kill the victim, a stepchild in the household, prob-lematic alcohol and illicit drug use, as well as mental health problems, are associated with a substantially higher risk of femi-cide. Little is known about the number of orphaned children who have instantane-ously lost both parents. Sparse attention has been focused on children whose moth-er was murdered: these are difficult cases for child psychiatry teams. Decis…

Potential Functional Significance of Brain-Type and Muscle-Type Nitric Oxide Synthase I Expressed in Adventitia and Media of Rat Aorta

1999

Abstract —Skeletal muscle and myocardium express μNOS I, an elongated splice variant of neuronal-type nitric oxide (NO) synthase (NOS I), and NOS III, endothelial-type NO synthase, respectively. This study was designed to elucidate whether vascular smooth muscle also contains a constitutively expressed NO synthase isoform. In the rat, μNOS I contains an insert of 102 nucleotides after nucleotide 2865 of the cDNA, yielding a protein of 164 kd. Reverse transcription-polymerase chain reaction with primers flanking this insert and with insert-specific primers indicated that endothelium-denuded rat aorta expresses both brain-type NOS I and μNOS I. RNase protection analyses with an antisense RNA…

A framework for remission in SLE

2017

ObjectivesTreat-to-target recommendations have identified ‘remission’ as a target in systemic lupus erythematosus (SLE), but recognise that there is no universally accepted definition for this. Therefore, we initiated a process to achieve consensus on potential definitions for remission in SLE.MethodsAn international task force of 60 specialists and patient representatives participated in preparatory exercises, a face-to-face meeting and follow-up electronic voting. The level for agreement was set at 90%.ResultsThe task force agreed on eight key statements regarding remission in SLE and three principles to guide the further development of remission definitions:1. Definitions of remission wi…

Are polymorphisms of the β3 -adrenoceptor gene associated with an altered bladder function?

2012

Aims As the presence of a Trp64Arg polymorphism of the gene encoding the β3-adrenoceptor (B3AR) has been linked to the presence of overactive bladder, we investigated whether additional polymorphisms are detectable in this gene and explore their relationships parameters related to lower urinary tract function. Methods The coding region and adjacent stretches of the B3AR gene was sequenced in 91 patients. In total, 1015 patients from a single academic hospital were genotyped for the presence of two single nucleotide polymorphisms. Symptom scores and parameters from pressure-flow studies were analyzed relative to genotype in the B3AR gene. Results No frequent novel polymorphisms were detected…

Galloway-Mowat syndrome: New insights from bioinformatics and expression during Xenopus embryogenesis.

2021

Abstract Galloway-Mowat syndrome (GAMOS) is a rare developmental disease. Patients suffer from congenital brain anomalies combined with renal abnormalities often resulting in an early-onset steroid-resistant nephrotic syndrome. The etiology of GAMOS has a heterogeneous genetic contribution. Mutations in more than 10 different genes have been reported in GAMOS patients. Among these are mutations in four genes encoding members of the human KEOPS ( k inase, e ndopeptidase and o ther p roteins of small s ize) complex, including OSGEP, TP53RK, TPRKB and LAGE3. Until now, these components have been functionally mainly investigated in bacteria, eukarya and archaea and in humans in the context of t…

Cystinuria subtype and nephrolithiasis

1999

Carbon isotope geochemistry and geochronological constraints of the Neoproterozoic Sirohi Group from northwest India

2012

a b s t r a c t The early Neoproterozoic carbonates of the Sirohi Group, northwestern India, were studied for geochronology as well as for oxygen and carbon isotopes across three different sections to understand their relationship with contemporaneous global events. New single zircon Pb-Pb evaporation data con- strain the age of the Sirohi Group between ca. 920 and ca. 820 Ma, though actual span for deposition of the carbonates may be little shorter taking into allowance the time for peneplanation. Narrow range in variation of 18O values is generally observed in the carbonate which is consistent with generally well-preserved original compositions. Two sections (SA and SS) out of the three t…

Outcomes for Geriatric Urolithiasis Patients aged ≥80 Years Compared to Patients in Their Seventies

2022

Abstract Background Demographic changes are leading to an increase in geriatric urolithiasis patients aged ≥70 yr. Published data regarding their management remain sparse. In particular, for the subgroup of patients aged ≥80 yr there is a lack of evidence supporting the hypothesis that stone-removing treatment is effective, safe, and beneficial. Objective To examine the efficiency and safety of stone-removing treatment in geriatric urolithiasis patients aged ≥80 yr compared to their younger geriatric counterparts aged 70–79 yr against the background of their respective life expectancy. Design, setting, and participants Data for the study cohort were extracted from an institutional review bo…