Search results for "NETWORK"
showing 10 items of 7718 documents
An Original Convolution Model to analyze Graph Network Distribution Features
2022
Modern Graph Theory is a newly emerging field that involves all of those approaches that study graphs differently from Classic Graph Theory. The main difference between Classic and Modern Graph Theory regards the analysis and the use of graph's structures (micro/macro). The former aims to solve tasks hosted on graph nodes, most of the time with no insight into the global graph structure, the latter aims to analyze and discover the most salient features characterizing a whole network of each graph, like degree distributions, hubs, clustering coefficient and network motifs. The activities carried out during the PhD period concerned, after a careful preliminary study on the applications of the…
MicroRNAs in Colorectal Cancer Drug Resistance: Shooters become Targets
2013
Copyright: © 2013 Fanale D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. MicroRNAs (MiRNAs) are involved in the regulation of several biological processes such as development, differentiation, metabolism, apoptosis and proliferation. Recently, it has been shown that deregulated expression of miRNAs are present in different human cancers, suggesting a potential role in carcinogenesis [1,2]. Recent evidence suggests that miRNAs may represent potential new therapeutic approaches in patients with dru…
Soft Topographic Map for Clustering and Classification of Bacteria
2007
In this work a new method for clustering and building a topographic representation of a bacteria taxonomy is presented. The method is based on the analysis of stable parts of the genome, the so-called “housekeeping genes”. The proposed method generates topographic maps of the bacteria taxonomy, where relations among different type strains can be visually inspected and verified. Two well known DNA alignement algorithms are applied to the genomic sequences. Topographic maps are optimized to represent the similarity among the sequences according to their evolutionary distances. The experimental analysis is carried out on 147 type strains of the Gammaprotebacteria class by means of the 16S rRNA…
Le Dislipidemie Genetiche. Il Progetto LIPIGEN
2011
Le Dislipidemie genetiche rappresentano un gruppo di patologie dell’Adulto e pediatriche che interessano nel nostro paese un numero considerevole di individui. Alcune di esse come le Ipercolesterolemie determinano un elevatissimo rischio cardiovascolare. Altre si associano a presentazioni cliniche polimorfe, specie in età pediatrica. Una proporzione rilevante di pazienti non viene diagnosticato e per la stragrande maggioranza di soggetti affetti da una di queste forme la diagnosi genetico-molecolare non è sempre disponibile. Allo scopo di risolvere tali criticità, la SISA si è fatta promotore del progetto LIPIGEN, un network strutturato per la gestione clinica e di laboratorio delle Dislipi…
IL PROGETTO LIPIGEN: UN AGGIORNAMENTO
2012
The sicilian network for inflammatory bowel disease (SN-IBD): preliminary data on efficacy of biological therapy.
2017
Introduction: The monitoring of appropriateness, costs, and clinical outcomes of biological therapy in inflammatory bowel disease (IBD) is a relevant need. Aims & Methods: We aimed to evaluate all these issues in Sicily through a webbased network of all prescribing centers. The Sicilian Network for Inflammatory Bowel Disease (SN-IBD) is composed by a super Hub coordinator centre and five Hub plus ten Spoke centres. From January 2013, all IBD patients starting a biological agent (incident cases) or already on treatment (prevalent cases) were entered in a web based software. Herein we report data of incident cases about the efficacy of biological therapy after twelve weeks and one year of…
The sicilian network of biological therapy in inflammatory bowel disease: preliminary data from a prospective study on efficacy and safety
2017
Background and aim: The monitoring of appropriateness and costs of biological therapy in Inflammatory bowel disease (IBD) is a relevant need. We aimed to evaluate appropriateness, efficacy and safety of biological therapy in IBD in Sicily through a web based network of prescribing centers. Material and methods: The Sicilian network for the monitoring of biological therapy in IBD is composed by a super Hub coordinator center and five Hub plus ten Spoke centers. From January 2013 all IBD patients starting a biological agent (incident cases) or already on treatment (prevalent cases) were entered in a web based software. Herein we report data on remission and response after twelve weeks of biol…
The Sicilian network of biological therapy in inflammatory bowel disease: preliminary data on efficacy .
2017
Background: The monitoring of appropriateness, costs, and clinical outcomes of biological therapy in inflammatory bowel disease (IBD) is a relevant need. We aimed to evaluate all these issues in Sicily through a web based network of all prescribing centers. Methods: From January 2013, all IBD patients starting a biological agent (incident cases) or already on treatment (prevalent cases) were entered in a web based software. Herein we report data of incident cases about the efficacy of biological therapy after twelve weeks and one year of treatment. Results: From January 2013 to October 2016, 1475 patients were included. Incident cases were 1090. Considering that 16% of patients experienced …
Sistema d'accoglienza e fabbisogni formativi
2007
Il contributo contenuto in questo capitolo, vuole indagare il sistema di relazioni esistenti tra turista-imprese, turista-enti pubblici, turista-comunità locale, nei tre ambiti territoriali. L’analisi accerta la presenza di relazionalità tra gli attori, verificandone l’intensità e la direzione, adottando una metodologia statistica, che fa uso di indicatori sintetici, sulla base dei dati raccolti in fase di rilevazione. I paragrafi seguenti, riportano per ciascuna relazione (turista verso la comunità e viceversa; turista verso gli enti, e viceversa; turista verso imprese e viceversa), la misura della relazionalità. Ciò consente di tracciare la mappa delle relazioni presenti all’interno di ci…
La Sicilia nel FP7: attori, progetti e reti
2013
I finanziamenti europei al sistema della Ricerca, Sviluppo e Innovazione (RSI) rappresentano un contributo fondamentale alla crescita della competitività delle economie regionali. Le risorse comunitarie si vanno ad integrare con quelle statali e regionali a sostegno delle imprese, contribuendo all’attivazione di numerose iniziative di ricerca da parte di chi nell’ambito di un partenariato unisce le proprie competenze e strutture produttive attorno ad un’idea progettuale più o meno prossima al mercato. Questo studio prende in esame la partecipazione del sistema della ricerca e produttivo siciliano (in primis imprese, università, istituti di ricerca) al principale programma europeo per la RSI…