Search results for "NETWORKS"
showing 10 items of 3260 documents
Prediction of bone mass gain by bone turnover parameters after parathyroidectomy for primary hyperparathyroidism: neural network software statistical…
2006
Background Primary hyperparathyroidism (pHPT) is the most frequent endocrine hypersecretion disease, and parathyroidectomy is the only curative option, since pharmacologic therapy reduces hypercalcemia but does not impede parathyroid hormone hypersecretion. According to guidelines from the National Institutes of Health, parathyroidectomy is associated with bone mass increase in some asymptomatic patients, while in others bone mass is not changed after surgery. Therefore, we performed the present study in an attempt to elucidate whether a preoperative biochemical bone parameter can be predictive of a significant vertebral bone mass increase in patients with pHPT. Methods For each patient we …
The complexity of graph languages generated by hyperedge replacement
1990
Although in many ways, hyperedge replacement graph grammars (HRGs) are, among all graph generating mechanisms, what context-free Chomsky grammars are in the realm of string rewriting, their parsing problem is known to be, in general, NP-complete. In this paper, the main difficulty in HRG parsing is analysed and some conditions on either grammar or input graphs are developed under which parsing can be done in polynomial time. For some of the cases, the parsing problem is shown to be log-space reducible to context-free string parsing.
Search for standard model Higgs bosons produced in association with W bosons.
2007
We report on the results of a search for standard model Higgs bosons produced in association with W bosons from p-pbar collisions at root s = 1.96 TeV. The search uses a data sample corresponding to approximately 1 fb-1 of integrated luminosity. Events consistent with the W to l-nu and H to b-bbar signature are selected by triggering on a high-pT electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light flavor jets, increasing the b-jet purity in the sample and thereby reducing the background to Higgs boson production. We observe no excess l-nu-b-bbar production beyond the …
CORMORANT
2019
People own and carry an increasing number of ubiquitous mobile devices, such as smartphones, tablets, and notebooks. Being small and mobile, those devices have a high propensity to become lost or stolen. Since mobile devices provide access to their owners' digital lives, strong authentication is vital to protect sensitive information and services against unauthorized access. However, at least one in three devices is unprotected, with inconvenience of traditional authentication being the paramount reason. We present the concept of CORMORANT, an approach to significantly reduce the manual burden of mobile user verification through risk-aware, multi-modal biometric, cross-device authentication…
A secure architecture for P2PSIP-based communication systems
2009
Today, Peer-to-Peer SIP based communication systems have attracted much attention from both academia and industry. The decentralized nature of P2P might provide the distributed peer-to-peer communication system without help of the traditional SIP server. However, it comes to the cost of reduced manageability and therefore causes security problems, e.g. distrust, privacy leaks, unpredictable availability, etc. In this paper, we investigate on P2PSIP security issues and propose a proxy-based system architecture that improves security during P2PSIP session initiation. The main issues considered in this architecture include Source inter-working, Encryption & Decryption, Policy Management, Desti…
SELDI-TOF-MS ProteinChip array profiling of tears from patients with dry eye.
2005
Protein and peptides in tears play an important role in ocular surface diseases. In previous studies, changes have been demonstrated in the electrophoretic protein profiles of patients with dry eye. The purpose of this work was to determine the usefulness of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) ProteinChip Array (Ciphergen Biosystems, Inc., Fremont, CA) technology for the automated analysis of proteins and peptides in tear fluid.Patients with dry eye (DRY, n = 88) and healthy subjects (CTRL, n = 71) were examined. Their tear proteins were analyzed using SELDI-TOF-MS ProteinChip Arrays with three different chromatographic surfaces (CM10…
Anatomical Network Comparison of Human Upper and Lower, Newborn and Adult, and Normal and Abnormal Limbs, with Notes on Development, Pathology and Li…
2015
How do the various anatomical parts (modules) of the animal body evolve into very different integrated forms (integration) yet still function properly without decreasing the individual’s survival? This long-standing question remains unanswered for multiple reasons, including lack of consensus about conceptual definitions and approaches, as well as a reasonable bias toward the study of hard tissues over soft tissues. A major difficulty concerns the non-trivial technical hurdles of addressing this problem, specifically the lack of quantitative tools to quantify and compare variation across multiple disparate anatomical parts and tissue types. In this paper we apply for the first time a powerf…
Hereditariness of Aortic Tissue: In-Vitro Time-Dependent Failure of Human and Porcine Specimens
2018
This study aims to investigate the time dependent failure of aortic tissues for pathological and healthy samples by biomechanical testing. The experimental campaign has involved human pathological tissue and healthy swine tissue as preliminary study towards the development of novel failure criteria.
Transcriptome Analysis of Ullrich Congenital Muscular Dystrophy Fibroblasts Reveals a Disease Extracellular Matrix Signature and Key Molecular Regula…
2015
Background Collagen VI related myopathies encompass a range of phenotypes with involvement of skeletal muscle, skin and other connective tissues. They represent a severe and relatively common form of congenital disease for which there is no treatment. Collagen VI in skeletal muscle and skin is produced by fibroblasts. Aims & Methods In order to gain insight into the consequences of collagen VI mutations and identify key disease pathways we performed global gene expression analysis of dermal fibroblasts from patients with Ullrich Congenital Muscular Dystrophy with and without vitamin C treatment. The expression data were integrated using a range of systems biology tools. Results were validat…
(Discriminative) Pattern Discovery on Biological Networks
2017
This work provides a review of biological networks as a model for analysis, presenting and discussing a number of illuminating analyses. Biological networks are an effective model for providing insights about biological mechanisms. Networks with different characteristics are employed for representing different scenarios. This powerful model allows analysts to perform many kinds of analyses which can be mined to provide interesting information about underlying biological behaviors. The text also covers techniques for discovering exceptional patterns, such as a pattern accounting for local similarities and also collaborative effects involving interactions between multiple actors (for example …