Search results for "NETWORKS"
showing 10 items of 3260 documents
Low intensity vs. self-guided Internet-delivered psychotherapy for major depression: A multicenter, controlled, randomized study
2013
Abstract Background Major depression will become the second most important cause of disability in 2020. Computerized cognitive-behaviour therapy could be an efficacious and cost-effective option for its treatment. No studies on cost-effectiveness of low intensity vs self-guided psychotherapy has been carried out. The aim of this study is to assess the efficacy of low intensity vs self-guided psychotherapy for major depression in the Spanish health system. Methods The study is made up of 3 phases: 1.- Development of a computerized cognitive-behaviour therapy for depression tailored to Spanish health system. 2.- Multicenter controlled, randomized study: A sample (N=450 patients) with mild/mod…
Restrictions on data-driven political micro-targeting in Germany
2017
The revitalisation of canvassing in recent elections is strongly related to campaigns´ growing possibilities for analysing voter data to gain knowledge about their constituents, identifying their most likely voters and serving up personalised messages through individual conversations. The research literature about political micro-targeting hardly ever focusses on campaigns in parliamentary democracies with strict data protection laws. Based on in-depth expert interviews we introduce a framework of constraints in strategic political communication and reveal several restrictions on the macro, meso and micro levels which hinder the implementation of sophisticated data strategies in Germany. We…
Online Black-Markets: An Investigation of a Digital Infrastructure in the Dark
2021
AbstractThis paper investigates the functioning of Online Black-Markets (OBMs), i.e. a digital infrastructure operating in the Dark Net that enables the exchange of illegal goods such as drugs, weapons and fake digital identities. OBMs exist notwithstanding adverse conditions such as police interventions, scams and market breakdowns. Relying on a longitudinal case study, we focus on the dynamics of interactions among actors and marketplace technologies and we identify three mechanisms explaining OBMs operations. In particular, we show that OBMs infrastructure is the result of commoditization, platformization and resilience processes. Our contribution relies on the identification of communit…
Online pricing for demand-side management in a low-voltage resistive micro-grid via a Stackelberg game with incentive strategies
2022
It has been demonstrated that online pricing mechanisms are a viable solution for demand side management in power systems. This study deals with the analysis and design of a droop-controlled low-voltage resistive AC micro-grid network system. Such a system is subjected to a dynamic demand obtained from an online pricing mechanism, which is proposed as a novelty in the study of micro-grids. This mechanism is derived from a variation of the Stackelberg game, which includes the use of incentive strategies. First, a configuration in which a supplier announces an incentive function and (Formula presented.) -consumers’ reaction to the resulting personalised price is presented. Then, a detailed st…
Comparison of Functional Network Connectivity and Granger Causality for Resting State fMRI Data
2017
Functional network connectivity (FNC) and Granger causality have been widely used to identify functional and effective connectivity for resting functional magnetic resonance imaging (fMRI) data. However, the relationship between these two approaches is still unclear, making it difficult to compare results. In this study, we investigate the relationship by constraining the FNC lags and the causality coherences for analyzing resting state fMRI data. The two techniques were applied respectively to examine the connectivity within default mode network related components extracted by group independent component analysis. The results show that FNC and Granger causality provide complementary result…
Reti, Nuovi Settori e Sostenibilità
2014
Negli ultimi anni, anche a seguito del perdurare della crisi economica, gli studiosi delle diverse discipline, ivi compresi gli scienziati regionali, si sono interrogati su come riconnettersi a un sentiero virtuoso di crescita economica e sociale ai diversi livelli territoriali. Non vi è dubbio che la crisi abbia stimolato, in molti ambiti, la scoperta di nuovi paradigmi o la rivalutazione di schemi concettuali che stentavano ad affermarsi. Partendo da tale premessa, l’oggetto di questo volume è proprio quello di riflettere su come alcuni di questi nuovi paradigmi (in tema di reti, nuovi settori, sostenibilità) abbiano orientato l’indagine empirica territoriale e di raccogliere ed evidenzia…
Marketing communication metrics for social media
2011
The objective of this paper is to develop a conceptual framework for measuring the effectiveness of social media marketing communications. Specifically, we study whether the existing marketing communications performance metrics are still valid in the changing digitalised communications landscape, or whether it is time to rethink them, or even to devise entirely new metrics. Recent advances in information technology and marketing bring a need to re-examine measurement models. We combine two important research topics and set directions for potential future research. Metrics to measure marketing communications performance have developed towards a customer orientation. There is no broadly accep…
Network of Concepts and Ideas
2010
We present the results of an experiment designed to investigate the way information is organized and stored in the human brain. In particular, we are using controlled stimuli to reverse engineer the networks of ideas and concepts in order to answer the following questions. (1) Are the networks of ideas and concepts in the human brain invoked by verbal and visual stimuli distinct from each other? The answer appears to be no for the network of ideas and inconclusive for the network of concepts. (2) What is the topology of these networks? Our experimental results show that both are small-world networks, with the network of ideas being random and the network of concepts scale-free.
GAM/ZFp/ZNF512B is central to a gene sensor circuitry involving cell-cycle regulators, TGF beta effectors, Drosha and microRNAs with opposite oncogen…
2010
MicroRNAs (miRNAs) are small regulatory RNAs targeting multiple effectors of cell homeostasis and development, whose malfunctions are associated with major pathologies such as cancer. Herein we show that GAM/ZFp/ZNF512B works within an intricate gene regulatory network involving cell-cycle regulators, TGFβ effectors and oncogenic miRNAs of the miR-17-92 cluster. Thus, GAM impairs the transcriptional activation of the miR-17-92 promoter by c-Myc, downregulates miR-17-92 miRNAs differentially, and limits the activation of genes responsive to TGFβ canonical pathway. In contrast, TGFβ decreases GAM transcripts levels while differentially upregulating miR-17-92 miRNAs. In turn, miR-17, miR-20a a…
“Your ride has arrived” – Exploring the nexus between subjective well-being, socio-cultural beliefs, COVID-19, and the sharing economy
2021
This study aimed to identify and explain different facets of the sharing economy and to differentiate between micro- and macro-mobility services. We also aimed to examine the correlation between the sharing economy and subjective well-being, cultural beliefs, and COVID-19. An exploratory research technique with face-to-face semi-structured interviews was used to collect data from a sample of 22 rideshare app users in a developing country between January and May 2020 and in July 2020. The data were analyzed using the NVivo 12 application. The major findings suggest that, considering their scope and use, sharing economy technology and services can be divided into four major domains: (1) hospi…