Search results for "NEUROMUSCULAR"
showing 10 items of 363 documents
Integrative Neuromuscular Training Enhances Physical Fitness in 6- to 14-Year-Old Rugby Players.
2021
ABSTRACT Alonso-Aubin, DA, Picon-Martinez, M, Rebullido, TR, Faigenbaum, AD, Cortell-Tormo, JM, and Chulvi-Medrano, I. Integrative neuromuscular training enhances physical fitness in 6- to 14-year-old rugby players. J Strength Cond Res 35(8): 2263-2271, 2021-The purpose of this study was to assess the effects of an 8-week integrative neuromuscular training (INT) program on physical fitness measures in young rugby players. A sample of 138 male rugby players (age range, 6-14 years) was divided into 5 age-related groups: group 1 (G1) (n = 20; age, 7.05 ± 0.58), group 2 (G2) (n = 27; age, 8.57 ± 0.49), group 3 (G3) (n = 31; age, 11.02 ± 0.56), group 4 (G4) (n = 33; age, 13.12 ± 0.58, and group …
Expression of the Acetylcholine Receptor α-Subunit Gene is Associated with Paraneoplastic Myasthenia Gravis in Mixed Thymoma
2000
Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction [1]. The muscular AChR has been extensively characterized [2], but the etiology of MG is still obscure. Whether the muscular AChR or another (auto)antigen plays a role during the initiation of MG is unknown [3]. The muscular AChR is a pentameric ion channel composed of four different subunits. The α-subunit contains the acetylcholine binding site and the main epitopes recognized by MG autoantibodies [2]. The human muscle AChR α-subunit exists as two isoforms, P3A- and P3A+ [4]. This is a result of alternative splicing of the P3A exon located betwee…
Advances on Cellular Clonotypic Immunity in Amyotrophic Lateral Sclerosis.
2022
Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disease, characterized by the progressive degeneration of the upper and lower motor neurons in the cortex and spinal cord. Although the pathogenesis of ALS remains unclear, evidence concerning the role of the clonotypic immune system is growing. Adaptive immunity cells often appear changed in number, or in terms of their activation profiles, both peripherally and centrally; however, their role in ALS appears conflictive. Data from human and animal model studies, which are currently reported in the literature, show that each subset of lymphocytes and their mediators may mediate a protective or toxic mechanism in ALS, affecting both…
Taste, movement, and death: varying effects of new prospero mutants during Drosophila development
2003
0022-3034 (Print) Comparative Study Journal Article Research Support, Non-U.S. Gov't; The PGal4 transposon inserted upstream of the pan-neural gene prospero (pros) causes several neural and behavioral defects in the Voila(1) strain. The precise excision of the transposon simultaneously rescued all these defects whereas its unprecise excision created new pros(V) alleles, including the null allele pros(V17). Here, we describe the relationship between the genetic structure of pros locus, larval locomotion, and larval gustatory response. These two behaviors showed varying degrees of variation depending upon the pros allele. We also found a good relation between behavioral alteration, the level …
Effects of far-infrared sauna bathing on recovery from strength and endurance training sessions in men
2015
Purpose: This study investigated effects of far-infrared sauna (FIRS) bathing on recovery from strength training and endurance training sessions, but also possible differences between FIRS and traditional (TRAD) Finnish sauna bathing. Methods: Ten healthy physically active male volunteers had on various days either a 60 min hypertrophic strength training session (STS) or a 34–40 min maximal endurance training session (ETS), which was following by 30 min bathing in special FIRS sauna at temperature of 35–50°C and humidity of 25–35%. After the sauna, subjects sat for 30 min at room temperature (21°C and 25–30% humidity). In comparison, 30 min of TRAD took place at 35–50°C and in 60–70% humidi…
Neurophysiological mechanisms of motor imagery : effects of associated somatosensory stimulation
2018
Mental training, which involves mentally simulating an action without motor output, is an effective stimulus to improve the maximal voluntary contraction. If only the motor pathway is activated, an activation of the somatosensory cortex is observed despite the lack of afferent feedback. Indeed, the motor imagery task efficiency is based in part on an interaction between motor and sensory pathway. Thus, it’s seems reasonable to think that the addition of sensory afferent feedback during motor imagery could potentiate the motor imagery effects and thus improve motor performance. In our first study, we showed that the addition of somatosensory stimulation of Ia-afferents during a motor imagery…
Gene-Related Protein Surplus Myopathies
2000
Numerous muscular dystrophies, such as dystrophinopathies, sarcoglycanopathies, and emerino- and laminopathies, are marked by the absence or reduction of mutant transsarcolemmal or nuclear proteins. In addition to these recently identified minus-proteinopathies, there are a growing number of plus-proteinopathies among neuromuscular disorders marked by a surplus or excess of endogenous proteins within muscle fibers of different, i.e., nontranssarcolemmal and nonnuclear types. These proteins are often filamentous; for example, desmin and actin accrue in respective desmin-related myopathies, among which are entities marked by mutant desmin, true desminopathies, and actinopathy, the latter ofte…
Alternative methods for strength development : the case of motor imagery and neuromuscular electrical stimulation
2020
An intense practice of resistance training, i.e. with heavy loads and a low number of repetitions, can cause injuries. To avoid them or limit detraining after an injury, alternative training methods have been developed. These methods have a double target since they also allow populations with different pathologies to practice a physical activity. This thesis focused particularly on the neuromuscular system and the mechanisms involved in strength development on plantar flexors muscles following motor imagery (MI), i.e. mental simulation of a movement without its concomitant motor output, and neuromuscular electrical stimulation (NMES), i.e. evoking contractions through electrical current app…
Physiological responses of running intermittent exercises
2012
The aims of the present work were to analyze the physiological responses during intermittent exercise and to determine; i) an field test to assess the maximal aerobic velocity (MAV) for intermittent exercise; ii) the type of intermittent exercise could elicit maximal oxygen uptake (VO2max); iii) the physiological and neuromuscular factors that could limit intermittent exercise duration.The first study demonstrated that the MAV (MAV45-15) reached at the end of an incremental intermittent (45s run/ 15s rest) field test (45-15FIT) was relevant to elicit a high percentage of VO2max during a 30s-30s intermittent training session. The second and third studies demonstrated that intermittent exerci…
Effect of depth of neuromuscular blockade on the abdominal space during pneumoperitoneum establishment in laparoscopic surgery.
2015
To evaluate the effect of neuromuscular blockade (NMB) upon the abdominal space during pneumoperitoneum establishment in laparoscopic surgery, comparing moderate NMB and deep NMB.Prospective, randomized, crossover clinical trial.Operating room.Seventy-six American Society of Anesthesiologists 1 to 2 patients scheduled for elective laparoscopic surgery.Two independent evaluations were performed at the establishment of pneumoperitoneum for a preset intraabdominal pressures (IAPs) of 8 and 12 mm Hg, both during moderate NMB (train-of-four count, 1-3) and deep NMB (posttetanic count,5). Rocuronium was used to induce NMB, and sugammadex was used for reversal.We evaluated (i) the volume of CO2 in…