Search results for "NEWA"

showing 10 items of 2491 documents

Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3

2019

International audience; Self-renewal and differentiation of pluripotent murine embryonic stem cells (ESCs) is regulated by extrinsic signaling pathways. It is less clear whether cellular metabolism instructs developmental progression. In an unbiased genome-wide CRISPR/Cas9 screen, we identified components of a conserved amino-acid-sensing pathway as critical drivers of ESC differentiation. Functional analysis revealed that lysosome activity, the Ragulator protein complex, and the tumor-suppressor protein Folliculin enable the Rag GTPases C and D to bind and seclude the bHLH transcription factor Tfe3 in the cytoplasm. In contrast, ectopic nuclear Tfe3 represses specific developmental and met…

MaleTranscription GeneticGTPaseGTP PhosphohydrolasesPATHWAYMice0302 clinical medicineNeural Stem CellsCRISPRTUMOR-SUPPRESSORCell Self RenewalPhosphorylationSPECIFICATIONdevelopmental disorder0303 health sciencesGenomeBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCell DifferentiationMouse Embryonic Stem CellsFlcndifferentiationCell biologymedicine.anatomical_structuremTORMolecular MedicineFemaleSignal transductionProtein BindingSignal TransductionRECRUITMENTBiology03 medical and health sciencesRag GTPasesLysosomeGeneticsmedicineAnimalsHumansPoint MutationNAIVE PLURIPOTENCYAMINO-ACID LEVELSTranscription factorAllelesPI3K/AKT/mTOR pathway030304 developmental biologyCOMPLEXFOLLICULINRagulatorCell Biologypluripotencyembryonic stem cellEmbryonic stem cellTfe3[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsCytoplasmLysosomes030217 neurology & neurosurgeryCell Stem Cell
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Renewable energy sources for energy consumption needs of Malta Island in Mediterranean sea

2016

The main purpose of this paper is to analyse the energetic condition of the Maltese islands and its electrical energy production, focusing on the employment of Renewable Energies in order to increase its energy independence. The main renewable source here proposed is wave energy: thanks to its strategic position, Malta will be able to produce electrical energy using an innovative type of Wave Energy Converter (WEC) based on the prototype of linear generator realized by University of Palermo. The use of this new technology will be able to cut down the electrical energy production from traditional power plants and, consequently, the greenhouse gases emissions (GHG). The procedures applied in …

Malta.Point AbsorberMediterranean SeaWECRenewable EnergyWave EnergyIsland
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Suitability of some existing damage indexes for assessing agreements in maintenance and management of museum climatization systems

2020

Heating, Ventilating and Air-Conditioning systems in museums are called to properly control important microclimate parameters, not only for visitors’ wellbeing, but mostly for the preservation of works of art. Accordingly, in case of interruptions to Heating, Ventilating and Air-Conditioning systems, due to maintenance interventions or drawbacks, it is essential to guarantee the acceptable break from service to which possible damages for the works of art are related. In this regard, the aim of this work is to introduce a simple indicator to support curators in regulating the stipulation of contracts with external companies, a more effective management and maintenance of the Heating, V…

Management and maintenance service contractSettore ING-IND/11 - Fisica Tecnica Ambientalelcsh:TRenewable Energy Sustainability and the EnvironmentEnvironmental conditionHeating ventilating and air-conditioningventilating and air-conditioning management and maintenance service contractEnergy Engineering and Power TechnologyheatingEnvironmental Science (miscellaneous)Environmental economicslcsh:Technologylcsh:HD72-88environmental conditionslcsh:Economic growth development planningWorks of art preservationeconomic cost.risk indexesEconomic costRisk indexeMuseumEconomic costBusinessmuseumsWater Science and Technology
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Mitigation of greenhouse gas emissions by adopting anaerobic digestion technology on dairy, sow and pig farms in Finland

2011

Abstract The impact of anaerobic digestion (AD) technology on mitigating greenhouse gas (GHG) emissions from manure management on typical dairy, sow and pig farms in Finland was compared. Firstly, the total annual GHG emissions from the farms were calculated using IPCC guidelines for a similar slurry type manure management system. Secondly, laboratory-scale experiments were conducted to estimate methane (CH4) potentials and process parameters for semi-continuous digestion of manures. Finally, the obtained experimental data were used to evaluate the potential renewable energy production and subsequently, the possible GHG emissions that could be avoided through adoption of AD technology on th…

Manure managementta115Waste managementRenewable Energy Sustainability and the Environmentbusiness.industryEnvironmental engineeringengineering.materialRenewable energyAnaerobic digestionBiogasEnteric fermentationGreenhouse gasengineeringEnvironmental scienceFertilizerbusinessRenewable resourceRenewable Energy
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A sustainable phenolic compound extraction system from olive oil mill wastewater

2017

Abstract The reduction of environmental impact and the achievement of economic advantages based on by-product recovery is the aim of applying methodologies for phenolic compounds extraction from Olive Oil Mill Wastewater. Volume reduction of Olive Oil Mill Wastewater could generate important advantages in terms of waste disposal cost abatement and, in addition, reuse in the production of foods with health properties could lead to economic benefits. Despite the fact that literature shows that several techniques have been developed, few economic approaches have been presented. This paper assesses the economic feasibility of a system based on membrane filtration and reverse osmosis processes f…

Marginal costEngineeringStrategy and Management010501 environmental sciencesReuse01 natural sciencesNet present valueIndustrial and Manufacturing Engineering0404 agricultural biotechnologySettore ING-IND/17 - Impianti Industriali MeccaniciReverse osmosisMalaxation0105 earth and related environmental sciencesGeneral Environmental ScienceOlive oil mill wastewaters; Phenolic compound; Membrane filtration; Net present value; Payback timeWaste managementRenewable Energy Sustainability and the Environmentbusiness.industryOlive oil mill wastewaters Phenolic compound Membrane filtration Net present value Payback time04 agricultural and veterinary sciences040401 food scienceSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeWastewaterSustainabilitybusinessWaste disposalJournal of Cleaner Production
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Optimization of Wave Energy Converter: DEIM Point Absorber II

2018

The paper presents a possible solution to optimize a wave energy converter, device able to exploit the wave energy resource. The utilization of this technology shows also positive aspects, thanks to the limited visual and environmental impacts. This system could be also installed in reserved areas, being similar to signal buoys, simplifying the problem of energy supply in small islands. In order to exploit the wave energy potential in the Mediterranean Sea, the department of Energy of Palermo University realized a first prototype of the electrical linear generator, that is the main component of the wave energy converter. This electrical machine can be operated by a two-floating buoys system…

Marine energypoint absorber.sea waverenewable source
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High frequency modeling technique for three phase power electronics module

2015

Nowadays, the high integrated power electronics modules (PMs), characterized by high speed, low loss and hard ware miniaturization, represent a new technology that meets the emerging demands of many applications, such us vehicle and home appliance, renewable energy sources in smart grid. The integration process and the high switching speeds increase the PM electromagnetic emissions that can create electromagnetic interference (EMI) with electric/electronic devices near the PMs. For this reason, electromagnetic compatibility (EMC) have to be carefully considered, yet in the design phase, to guarantee the reliability of PM systems. In this paper a method to develop a high frequency (HF) model…

MarketingEngineeringRenewable Energy Sustainability and the Environmentbusiness.industryElectromagnetic compatibilityEnergy Engineering and Power TechnologyPower moduleElectromagnetic interferenceElectromagnetic interferenceStrategy and Management1409 Tourism Leisure and Hospitality ManagementSmart gridEMIHigh frequency modelingPower modulePower electronicsMiniaturizationElectronic engineeringElectromagnetic compatibilityElectronicsbusinessSettore ING-INF/07 - Misure Elettriche E Elettroniche2015 5th International Conference on Electric Utility Deregulation and Restructuring and Power Technologies (DRPT)
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Ūdeņraža enerģētikas mārketinga nepieciešamības attīstīšana Latvijā

2013

Elektroniskā versija nesatur pielikumus

MarketingHydrogen technologyRenewable energyMārketingsatjaunojami energoresursipatērētāju attieksmeMarketing strategyEkonomikaSocial marketingūdeņradis enerģētikāConsumer attitude
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ℓ1-Penalized Methods in High-Dimensional Gaussian Markov Random Fields

2016

In the last 20 years, we have witnessed the dramatic development of new data acquisition technologies allowing to collect massive amount of data with relatively low cost. is new feature leads Donoho to define the twenty-first century as the century of data. A major characteristic of this modern data set is that the number of measured variables is larger than the sample size; the word high-dimensional data analysis is referred to the statistical methods developed to make inference with this new kind of data. This chapter is devoted to the study of some of the most recent ℓ1-penalized methods proposed in the literature to make sparse inference in a Gaussian Markov random field (GMRF) defined …

Markov kernelMarkov random fieldMarkov chainComputer scienceStructured Graphical lassoVariable-order Markov model010103 numerical & computational mathematicsMarkov Random FieldMarkov model01 natural sciencesGaussian random field010104 statistics & probabilityHigh-Dimensional InferenceMarkov renewal processTuning Parameter SelectionMarkov propertyJoint Graphical lassoStatistical physics0101 mathematicsSettore SECS-S/01 - StatisticaGraphical lasso
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Effect of the height-to-diameter ratio on the mass transfer and mixing performance of a biotrickling filter

2017

BACKGROUND Biotrickling filters (BTFs) are among the most widely used biological technologies for air pollution control. The pollutant removal rate in BTFs relies to a large extent on its gas–liquid mass transfer performance. Therefore, knowledge of the design parameters affecting the mass transfer and mixing performance of full-scale BTFs is of paramount importance. RESULTS This work showed that the height-to-diameter (H/D) ratio is an important parameter in the design of BTFs devoted to air pollution control. The H/D ratio significantly affected the mass transfer and mixing performance of the BTF with and without additional stirring in the holding tank. It was observed that under the same…

Mass transfer coefficientWork (thermodynamics)Materials scienceRenewable Energy Sustainability and the EnvironmentGeneral Chemical EngineeringOrganic ChemistryMixing (process engineering)Environmental engineering02 engineering and technologyMechanics010501 environmental sciences021001 nanoscience & nanotechnology01 natural sciencesPollutionInorganic ChemistryDiameter ratioFilter (large eddy simulation)Fuel TechnologyLiquid velocityMass transferHolding tank0210 nano-technologyWaste Management and Disposal0105 earth and related environmental sciencesBiotechnologyJournal of Chemical Technology & Biotechnology
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