Search results for "NFOL"
showing 10 items of 144 documents
The Yeast eIF2 Kinase Gcn2 Facilitates H 2 O 2 -Mediated Feedback Inhibition of Both Protein Synthesis and Endoplasmic Reticulum Oxidative Folding du…
2021
Recombinant protein production is a known source of oxidative stress. However, knowledge of which reactive oxygen species are involved or the specific growth phase in which stress occurs remains lacking. Using modern, hypersensitive genetic H2O2-specific probes, microcultivation, and continuous measurements in batch culture, we observed H2O2 accumulation during and following the diauxic shift in engineered Saccharomyces cerevisiae, correlating with peak α-amylase production. In agreement with previous studies supporting a role of the translation initiation factor kinase Gcn2 in the response to H2O2, we find that Gcn2-dependent phosphorylation of eIF2α increases alongside translational atten…
Differences in Participation and Performance Trends in Age Group Half and Full Marathoners
2014
International audience; Recent studies investigated participation and performance trends in age group half marathoners and full marathoners for a single event. The present study investigated participation and performance trends in age group athletes in all half marathons and full marathons held in a single country during a given period of time. Changes in running performance and age of 226,754 half marathoners and 86,419 full marathoners competing in Switzerland between 2000 and 2010 were analyzed using linear regression analyses. The number of half marathoners increased (P < 0.01) from 2000 to 2010 for both men (+231%) and women (+299%). In contrast, the number of male and female full mara…
Is Body Fat a Predictor of Race Time in Female Long-Distance Inline Skaters?
2010
Purpose The aim of this study was to evaluate predictor variables of race time in female ultra-endurance inliners in the longest inline race in Europe. Methods We investigated the association between anthropometric and training characteristics and race time for 16 female ultra-endurance inline skaters, at the longest inline marathon in Europe, the ‘Inline One-eleven’ over 111 km in Switzerland, using bi- and multivariate analysis. Results The mean (SD) race time was 289.7 (54.6) min. The bivariate analysis showed that body height (r=0.61), length of leg (r=0.61), number of weekly inline skating training sessions (r=-0.51) and duration of each training unit (r=0.61) were significantly correl…
Running speed during training and percent body fat predict race time in recreational male marathoners.
2012
&nbsp;Background: Recent studies have shown that personal best marathon time is a strong predictor of race time in male ultramarathoners. We aimed to determine variables predictive of marathon race time in recreational male marathoners by using the same characteristics of anthropometry and training as used for ultramarathoners.Methods: Anthropometric and training characteristics of 126 recreational male marathoners were bivariately and multivariately related to marathon race times.Results: After multivariate regression, running speed of the training units (&beta;=-0.52, P&lt;0.0001) and percent body fat (&beta;=0.27, P &lt;0.0001) were the two variables most strongly cor…
Genomic organization and promoter characterization of the gene encoding a putative endoplasmic reticulum chaperone, ERp29
2002
Abstract ERp29 is a soluble protein localized in the endoplasmic reticulum (ER) of eukaryotic cells, which is conserved in all mammalian species. The N-terminal domain of ERp29 displays sequence and structural similarity to the protein disulfide isomerase despite the lack of the characteristic double cysteine motif. Although the exact function of ERp29 is not yet known, it was hypothesized that it may facilitate folding and/or export of secretory proteins in/from the ER. ERp29 is induced by ER stress, i.e. accumulation of unfolded proteins in the ER. To gain an insight into the mechanisms regulating ERp29 expression we have cloned and characterized the rat ERp29 gene and studied in details …
"Table 7" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Unfolded Dijet conditional yields (Delta p_{T} > 3). Full markers represent p+Pb, open markers p+p
"Table 3" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Unfolded Dijet conditional yields. Full markers represent p+Pb, open markers p+p
"Table 5" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Ratio of unfolded Dijet conditional yields (P PB/ P P). Different colors correspond to different combinations of p_{T,1} and p_{T,2}
"Table 9" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Ratio of unfolded Dijet conditional yields (P PB/ P P) (Delta p_{T} > 3). Different colors correspond to different combinations of p_{T,1} and p_{T,2}
"Table 11" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS det…
2020
Unfolded azimuthal angular correlation distributions (Delta p_{T} > 3). Black markers represent p+Pb, red markers p+p