Search results for "NGAL"
showing 10 items of 1796 documents
Is ram-pressure stripping an efficient mechanism to remove gas in galaxies?
2017
We study how the gas in a sample of galaxies (M* > 10e9 Msun) in clusters, obtained in a cosmological simulation, is affected by the interaction with the intra-cluster medium (ICM). The dynamical state of each elemental parcel of gas is studied using the total energy. At z ~ 2, the galaxies in the simulation are evenly distributed within clusters, moving later on towards more central locations. In this process, gas from the ICM is accreted and mixed with the gas in the galactic halo. Simultaneously, the interaction with the environment removes part of the gas. A characteristic stellar mass around M* ~ 10e10 Msun appears as a threshold marking two differentiated behaviours. Below this mas…
Non-thermal pressure support in X-COP galaxy clusters
2018
Galaxy clusters are the endpoints of structure formation and are continuously growing through the merging and accretion of smaller structures. Numerical simulations predict that a fraction of their energy content is not yet thermalized, mainly in the form of kinetic motions (turbulence, bulk motions). Measuring the level of non-thermal pressure support is necessary to understand the processes leading to the virialization of the gas within the potential well of the main halo and to calibrate the biases in hydrostatic mass estimates. We present high-quality measurements of hydrostatic masses and intracluster gas fraction out to the virial radius for a sample of 12 nearby clusters with availab…
The non-Gaussian distribution of galaxies gravitational fields
2016
We perform a theoretical analysis of the observational dependence between angular momentum of the galaxy clusters and their mass (richness), based on the method introduced in our previous paper. For that we obtain the distribution function of astronomical objects (like galaxies and/or smooth halos of different kinds) gravitational fields due to their tidal interaction. Within the statistical method of Chandrasekhar we are able to show that the distribution function is determined by the form of interaction between objects and for multipole (tidal) interaction it is never Gaussian. Our calculation permits to demonstrate how the alignment of galaxies angular momenta depend on the cluster richn…
Searching for differences in Swift's intermediate GRBs
2010
Gamma-ray bursts are usually classified through their high-energy emission into short-duration and long-duration bursts, which presumably reflect two different types of progenitors. However, it has been shown on statistical grounds that a third, intermediate population is needed in this classification scheme, although an extensive study of the properties of this class has so far not been done. The large amount of follow-up studies generated during the Swift era allows us to have a suficient sample to attempt a study of this third population through the properties of their prompt emission and their afterglows. Our study is focused on a sample of GRBs observed by Swift during its first four y…
Hydrophobin (HFBI): a potential fusion partner for one-step purification of recombinant proteins from insect cells
2008
Hydrophobins play an important role in binding and assembly of fungal surface structures as well as in medium-air interactions. These, hydrophobic properties provide interesting possibilities when purification of macromolecules is concerned. In aqueous micellar two-phase systems, based on surfactants, the water soluble hydrophobins are concentrated inside micellar structures and, thus, distributed to defined aqueous phases. This, one-step purification is attractive particularly when large-scale production of recombinant proteins is concerned. In the present study the hydrophobin HFBI of Trichoderma reesei was expressed as an N-terminal fusion with chicken avidin in baculovirus infected inse…
Antifungal activity improved by coproduction of cyclodextrins and anabaenolysins in Cyanobacteria
2015
Department of Chemistry, Nanoscience Center, University of Jyväskylä, FI-40014, Jyväskylä, Finland Cyclodextrins are cyclic oligosaccharides widely used in the pharmaceutical industry to improve drug delivery and to increase the solubility of hydrophobic compounds. Anabaenolysins are lipopeptides produced by cyanobacteria with potent lytic activity in cholesterolcontaining membranes. Here, we identified the 23- To 24-kb gene clusters responsible for the production of the lipopeptide anabaenolysin. The hybrid nonribosomal peptide synthetase and polyketide synthase biosynthetic gene cluster is encoded in the genomes of three anabaenolysin-producing strains of Anabaena.We detected previously u…
Assessment of antifungal activity of extracts from nettle (Urtica dioica L.) against Alternaria solani = Ocena aktywności przeciwgrzybowej ekstraktów…
2015
(Urtica dioica L.) w stężeniach 2,5, 5,0, 10,0, 20,0, 40,0% wobec fitopatogennego szczepu Alternaria solani. Aktywność przeciwgrzybową ekstraktów z pokrzywy określono w oparciu o indeks tempa wzrostu grzybni oraz indeks kiełkowania zarodników. W badaniach określono również wpływ metod sterylizacji testowanych wyciągów na ich aktywność. Na podstawie uzyskanych wyników wykazano, iż ekstrakty sterylizowane parą wodną pod ciśnieniem nie wykazują aktywności przeciwgrzybowej. W przypadku ekstraktu z korzenia, który charakteryzował się większą aktywnością inhibicyjną, uzyskano zaledwie 7% redukcję tempa wzrostu grzybni. Natomiast ekstrakt z korzenia poddany sterylizacji przez sączenie ograniczał o…
A challenging case of chorioretinitis and skin lesions in a lung transplant recipient
2018
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Iron Induces Proliferation and Morphogenesis in Primmorphs from the Marine SpongeSuberites domuncula
2002
Dissociated cells from marine demosponges retain their proliferation capacity if they are allowed to form special aggregates, the primmorphs. On the basis of incorporation studies and septin gene expression, we show that Fe3+ ions are required for the proliferation of cells in primmorphs from Suberites domuncula. In parallel, Fe3+ induced the expression of ferritin and strongly stimulated the synthesis of spicules. This result is supported by the finding that the enzymatic activity of silicatein, converting organosilicon to silicic acid, depends on Fe3+. Moreover, the expression of a scavenger receptor molecule, possibly involved in the morphology of spicules, depends on the presence of Fe3…
Cardiorenal Syndrome: New Pathways and Novel Biomarkers
2021
Cardiorenal syndrome (CRS) is a multi-organ disease characterized by the complex interaction between heart and kidney during acute or chronic injury. The pathogenesis of CRS involves metabolic, hemodynamic, neurohormonal, and inflammatory mechanisms, and atherosclerotic degeneration. In the process of better understanding the bi-directional pathophysiological aspects of CRS, the need to find precise and easy-to-use markers has also evolved. Based on the new pathophysiological standpoints and an overall vision of the CRS, the literature on renal, cardiac, metabolic, oxidative, and vascular circulating biomarkers was evaluated. Though the effectiveness of different extensively applied biomark…