Search results for "NGAL"
showing 10 items of 1796 documents
Effect of Germacrene-Rich Essential Oil of Parentucellia latifolia (L.) Caruel Collected in Central Sicily on the Growth of Microorganisms Inhabiting…
2022
In the present study, the chemical composition of the essential oil from aerial parts of Parentucellia latifolia (L.) Caruel collected in Central Sicily was analyzed by gas chromatography and gas chromatography–mass spectrometry. The results showed the presence of sesquiterpene hydrocarbons, with germacrene D and germacrene B accounting, respectively, for 59.2% and 24.3% of the total oil. Different colonies of bacteria and fungi frequently affect cellulosic objects such as books stored in libraries and museums. The antibacterial and antifungal activity against some microorganisms infesting historical-artistic craftsmanship was determined, demonstrating that the essential oil was particular…
Influence of harvesting time on composition of the essential oil of Thymus capitatus (L.) Hoffmanns. & Link. growing wild in northern Sicily and its …
2019
One of the main factors affecting historical art crafts material is the biodeterioration performed by bacteria and fungi, in archives, museums or private collections. Several microorganisms cause degradation to the natural organic material such as fibers, woods, and dyes as well as to stone objects. These alterations produce deterioration of physical, chemical, mechanical and esthetic properties. Consequently, in this publication, we report the high antibacterial and antifungal activities of wild thyme essential oil, oil that can be used as an alternative natural tool in the fight against microorganisms affecting historical art crafts.Essential oil of the Thymus capitatus growing wild in no…
Momentum distributions of cosmic relics: Improved analysis
2022
We solve coupled momentum-dependent Boltzmann equations for the phase space distribution of cosmic relic particles, without resorting to approximations of assuming kinetic equilibrium or neglecting backscattering or elastic interactions. Our method is amendable to precision numerical computations. To test it, we consider two benchmark models where the momentum dependence of dark matter distribution function is potentially important: a real singlet scalar extension near the Higgs resonance and a sterile neutrino dark matter model with a singlet scalar mediator. The singlet scalar example shows that the kinetic equilibrium may hold surprisingly well even near sharp resonances. However, the in…
Self-interacting dark matter and cosmology of a light scalar mediator
2015
We consider a fermionic dark matter candidate interacting via a scalar mediator coupled with the Standard Model through a Higgs portal. We consider general setting including both scalar and pseudoscalar interactions between the scalar and fermion, and illustrate the relevant features for dark matter abundance, direct search limits and collider constraints. The case where dark matter has a self-interaction strength $\left\langle \sigma_V \right\rangle/m_\psi \sim 0.1-1 \,\mathrm{cm}^2/\mathrm{g}$ is strongly constrained, in particular by the Big Bang Nucleosynthesis. We show that these constraints can be alleviated by introducing a new light sterile neutrino $N$. The allowed region for the e…
Florence Nightingale as a Victorian career woman
2016
The chapter focuses on the role of Florence Nightingale (1820-1910) in turning nursing into a trained profession and a viable and respectable career option for Victorian women seeking employment outside of the home. Nightingale's accomplishments and her thoughts on women's lot in life as expressed in her essay "Cassandra", are presented against the backdrop of the ideology of separate spheres which circumscribes women within the domestic domain. The chapter discusses Nightingale's work in British military field hospitals during the Crimean War, her successful efforts to reform the ways in which such hospitals were run, and the establishment of the Nightingale School and Home for Nurses and …
Fighting Antibiotic Resistance: New Pyrimidine-Clubbed Benzimidazole Derivatives as Potential DHFR Inhibitors
2023
The present work describes the design and development of seventeen pyrimidine-clubbed benzimidazole derivatives as potential dihydrofolate reductase (DHFR) inhibitors. These compounds were filtered by using ADMET, drug-likeness characteristics calculations, and molecular docking experiments. Compounds 27, 29, 30, 33, 37, 38, and 41 were chosen for the synthesis based on the results of the in silico screening. Each of the synthesized compounds was tested for its in vitro antibacterial and antifungal activities using a variety of strains. All the compounds showed antibacterial properties against Gram-positive bacteria (Staphylococcus aureus and Staphylococcus pyogenes) as well as Gram-negativ…
The effects of grazing history, soil properties and stand structure on the communities of saprotrophic fungi in wood-pastures
2022
Wood-pastures are threatened anthropogenic biotopes that provide habitat for an extensive group of species. Here we studied the effect of management, grazing intensity, time since abandonment, historical land-use intensity, soil properties and stand conditions on communities of saprotrophic fungi in wood-pastures in Central Finland. We found that the proportion of broadleaved trees and soil pH are the major drivers in the communities of saprotrophic fungi in these boreal wood-pastures. In addition, tree species richness, soil moisture, historical land-use intensity and time since abandonment affected the communities of saprotrophic fungi. Current management or grazing intensity did not have…
MR2407444 (2009e:60101) Labuschagne, Coenraad C. A. Join-semilattices of integrable set-valued martingales. Thai J. Math. 5 (2007), no. 1, 53--69. (R…
2009
Join-semilattices of integrable set-valued martingales
Effects of ectopic expression of NGAL on doxorubicin sensitivity.
2012
Neutrophil gelatinase-associated lipocalin (NGAL, a.k.a Lnc2) is a member of the lipocalin family which has diverse roles including stabilizing matrix metalloproteinase-9 from auto-degradation and as siderocalins which are important in the transport of iron. NGAL also has important biological functions involved in immunity and inflammation as well as responses to kidney damage. NGAL expression has also been associated with certain neoplasia and is important in the metastasis of breast cancer. Many advanced cancer patients have elevated levels of NGAL in their urine and it has been proposed that NGAL may be a prognostic indicator for certain cancers (e.g. breast, brain, and others). NGAL exp…
The ALHAMBRA survey: evolution of galaxy clustering since z∼1
2014
We study the clustering of galaxies as function of luminosity and redshift in the range $0.35 < z < 1.25$ using data from the Advanced Large Homogeneous Area Medium Band Redshift Astronomical (ALHAMBRA) survey. The ALHAMBRA data used in this work cover $2.38 \mathrm{deg}^2$ in 7 independent fields, after applying a detailed angular selection mask, with accurate photometric redshifts, $��_z \lesssim 0.014 (1+z)$, down to $I_{\rm AB} < 24$. Given the depth of the survey, we select samples in $B$-band luminosity down to $L^{\rm th} \simeq 0.16 L^{*}$ at $z = 0.9$. We measure the real-space clustering using the projected correlation function, accounting for photometric redshifts uncert…