Search results for "NIP"
showing 10 items of 775 documents
Equivalence classes of permutations modulo descents and left-to-right maxima
2014
Abstract In a recent paper [2], the authors provide enumerating results for equivalence classes of permutations modulo excedances. In this paper we investigate two other equivalence relations based on descents and left-to-right maxima. Enumerating results are presented for permutations, involutions, derangements, cycles and permutations avoiding one pattern of length three.
A-Codes from Rational Functions over Galois Rings
2006
In this paper, we describe authentication codes via (generalized) Gray images of suitable codes over Galois rings. Exponential sums over these rings help determine--or bound--the parameters of such codes.
Polynomial method to study the entanglement of pure N-qubit states
2009
We present a mapping which associates pure N-qubit states with a polynomial. The roots of the polynomial characterize the state completely. Using the properties of the polynomial we construct a way to determine the separability and the number of unentangled qubits of pure N-qubit states.
An exact and efficient approach for computing a cell in an arrangement of quadrics
2006
AbstractWe present an approach for the exact and efficient computation of a cell in an arrangement of quadric surfaces. All calculations are based on exact rational algebraic methods and provide the correct mathematical results in all, even degenerate, cases. By projection, the spatial problem is reduced to the one of computing planar arrangements of algebraic curves. We succeed in locating all event points in these arrangements, including tangential intersections and singular points. By introducing an additional curve, which we call the Jacobi curve, we are able to find non-singular tangential intersections. We show that the coordinates of the singular points in our special projected plana…
Associative rings whose adjoint semigroup is locally nilpotent
2001
The set of all elements of an associative ring R, not necessarily with a unit element, forms a semigroup R ad under the circle operation \({r\circ s}={r+s+rs}\) on R. The ring R is called radical if R ad is a group. It is proved that the semigroup R ad is nilpotent of class n (in sense of A. Mal'cev or B. H. Neumann and T. Taylor) if and only if the ring R is Lie-nilpotent of class n. This yields a positive answer to a question posed by A. Krasil'nikov and independently considered by D. Riley and V. Tasic. It is also shown that the adjoint group of a radical ring R is locally nilpotent if and only if R is locally Lie-nilpotent.
The role of histamine in doxorubicin and teniposide-induced cardiotoxicity in dog and mouse.
1987
In previous studies we reported that teniposide (VM26) induced acute cardiac effects in dogs seem to be related to a release of histamine and that a prior treatment with chlorpheniramine, an H, histamine blocker, prevents the onset of this phenomenon. Since histamine and other vasoactive substances also seem to be involved in doxorubicin (DXR)-induced acute cardiac effects, experiments were undertaken in the aim to prevent, as in the case of VM26, the onset of this phenomenon by administering chlorpheniramine. Since DXR-induced chronic cardiomyopathy also seems to be related to the same mechanisms involved in the onset of acute cardiac effects induced by this drug, additional studies were …
Functionalized Poly(N-isopropylacrylamide)-Based Microgels in Tumor Targeting and Drug Delivery
2021
Over the past several decades, the development of engineered small particles as targeted and drug delivery systems (TDDS) has received great attention thanks to the possibility to overcome the limitations of classical cancer chemotherapy, including targeting incapability, nonspecific action and, consequently, systemic toxicity. Thus, this research aims at using a novel design of Poly(N-isopropylacrylamide) p(NIPAM)-based microgels to specifically target cancer cells and avoid the healthy ones, which is expected to decrease or eliminate the side effects of chemotherapeutic drugs. Smart NIPAM-based microgels were functionalized with acrylic acid and coupled to folic acid (FA), targeting the f…
Trading off accuracy for efficiency by randomized greedy warping
2016
Dynamic Time Warping (DTW) is a widely used distance measure for time series data mining. Its quadratic complexity requires the application of various techniques (e.g. warping constraints, lower-bounds) for deployment in real-time scenarios. In this paper we propose a randomized greedy warping algorithm for finding similarity between time series instances. We show that the proposed algorithm outperforms the simple greedy approach and also provides very good time series similarity approximation consistently, as compared to DTW. We show that the Randomized Time Warping (RTW) can be used in place of DTW as a fast similarity approximation technique by trading some classification accuracy for ve…
The association of depression and all-cause and cause-specific mortality: An umbrella review of systematic reviews and meta-analyses
2018
Background Depression is a prevalent and disabling mental disorder that frequently co-occurs with a wide range of chronic conditions. Evidence has suggested that depression could be associated with excess all-cause mortality across different settings and populations, although the causality of these associations remains unclear. Methods We conducted an umbrella review of systematic reviews and meta-analyses of observational studies. PubMed, PsycINFO, and Embase electronic databases were searched through January 20, 2018. Systematic reviews and meta-analyses that investigated associations of depression and all-cause and cause-specific mortality were selected for the review. The evidence was g…
Discovery of varlaxins, new aeruginosin-type inhibitors of human trypsins
2022
Low-molecular weight natural products display vast structural diversity and have played a key role in the development of novel therapeutics. Here we report the discovery of novel members of the aeruginosin family of natural products, which we named varlaxins. The chemical structures of varlaxins 1046A and 1022A were determined using a combination of mass spectrometry, analysis of one- and two-dimensional NMR spectra, and HPLC analysis of Marfey's derivatives. These analyses revealed that varlaxins 1046A and 1022A are composed of the following moieties: 2-O-methylglyceric acid 3-O-sulfate, isoleucine, 2-carboxy-6-hydroxyoctahydroindole (Choi), and a terminal arginine derivative. Varlaxins 10…