Search results for "NODAL"
showing 10 items of 264 documents
Dezinfekcijas līdzekļu un individuālo aizsarglīdzekļu ietekme uz māsas pašsajūtu ķirurģijas nodaļā
2022
Bakalaura darba tēmas nosaukums ir “Dezinfekcijas līdzekļu un individuālo aizsarglīdzekļu ietekme uz māsas pašsajūtu ķirurģijas nodaļā”. Ņemot vērā, ka dezinfekcijas līdzekļi tiek ražoti koncentrētāki, kā arī individuālie aizsarglīdzekļi tiek pielietoti aizvien vairāk, to pielietojums ir paredzēts, lai aizsargātu māsas un citu ārstniecības personāla un pacienta veselību, tomēr šie līdzekļi var ietekmēt māsas pašsajūtu- pasliktinot gan fizisko, gan psihoemocionālo stāvokli, tad par bakalaura darba mērķi tika izvirzīts- noskaidrot dezinfekcijas līdzekļu un individuālo aizsarglīdzekļu lietošanas ietekmi uz māsas pašsajūtu ķirurģijas nodaļā. Uzsākot pētījuma darbu, tika izvirzīts arī pētījuma j…
On Noncoercive (p, q)-Equations
2021
We consider a nonlinear Dirichlet problem driven by a (p, q)-Laplace differential operator (1 < q < p). The reaction is (p - 1)-linear near +/-infinity and the problem is noncoercive. Using variational tools and truncation and comparison techniques together with critical groups, we produce five nontrivial smooth solutions all with sign information and ordered. In the particular case when q = 2, we produce a second nodal solution for a total of six nontrivial smooth solutions all with sign information.
A distributed dynamic load balancer and its implementation on multi-transputer systems for molecular dynamics simulation
1990
Abstract A new and efficient approach is described to the dynamic load-balancing problem which is central in concurrent computing. A transputer-based implementation is tested on a molecular dynamics simulation of spinodal phase separation.
Least energy solutions to the Dirichlet problem for the equation −D(u) = f (x, u)
2017
Let be a bounded smooth domain in RN. We prove a general existence result of least energy solutions and least energy nodal ones for the problem −u = f(x, u) in u = 0 on ∂ (P) where f is a Carathéodory function. Our result includes some previous results related to special cases of f . Finally, we propose some open questions concerning the global minima of the restriction on the Nehari manifold of the energy functional associated with (P) when the nonlinearity is of the type f(x, u) = λ|u| s−2u − μ|u| r−2u, with s, r ∈ (1, 2) and λ,μ > 0.
Ectopic hbox12 Expression Evoked by Histone Deacetylase Inhibition Disrupts Axial Specification of the Sea Urchin Embryo
2015
Dorsal/ventral patterning of the sea urchin embryo depends upon the establishment of a Nodal-expressing ventral organizer. Recently, we showed that spatial positioning of this organizer relies on the dorsal-specific transcription of the Hbox12 repressor. Building on these findings, we determined the influence of the epigenetic milieu on the expression of hbox12 and nodal genes. We find that Trichostatin-A, a potent and selective histone-deacetylases inhibitor, induces histone hyperacetylation in hbox12 chromatin, evoking broad ectopic expression of the gene. Transcription of nodal concomitantly drops, prejudicing dorsal/ventral polarity of the resulting larvae. Remarkably, impairing hbox12 …
Function of RAR? and RAR?2 at the initiation of retinoid signaling is essential for avian embryo survival and for distinct events in cardiac morphoge…
2003
Avian embryogenesis requires retinoid receptor activation by the vitamin A active form, retinoic acid (RA), during neurulation. We conducted loss-of-function analysis in quail embryos by nutritional deprivation of RA and by blocking generation of retinoid receptors. Here we identify a distinct role for RARα2 in cardiac inflow tract morphogenesis and for RARγ in cardiac left/right orientation and looping morphogenesis. Blocking normal embryos with antisense oligonucleotides to RARα2 or RXRα diminishes GATA-4 transcripts, while blocking RARγ or RXRα diminishes nodal and Pitx2 transcripts; the expression of these genes in the heart forming region resembles that of the vitamin A-deficient embry…
Early asymmetric cues triggering the dorsal/ventral gene regulatory network of the sea urchin embryo
2014
Dorsal/ventral (DV) patterning of the sea urchin embryo relies on a ventrally-localized organizer expressing Nodal, a pivotal regulator of the DV gene regulatory network. However, the inceptive mechanisms imposing the symmetry-breaking are incompletely understood. In Paracentrotus lividus, the Hbox12 homeodomain-containing repressor is expressed by prospective dorsal cells, spatially facing and preceding the onset of nodal transcription. We report that Hbox12 misexpression provokes DV abnormalities, attenuating nodal and nodal-dependent transcription. Reciprocally, impairing hbox12 function disrupts DV polarity by allowing ectopic expression of nodal. Clonal loss-of-function, inflicted by b…
Lymphoid lesions of salivary glands : malignant and Benign
2007
Lesions of salivary glands with a prominent lymphoid component are a heterogeneous group of diseases that include benign reactive lesions and malignant neoplasms. Occasionally, these pathologic entities present difficulties in the clinical and pathological diagnosis and prognosis. Lymphoepithelial sialadenitis, HIV-associated salivary gland disease, chronic sclerosing sialadenitis, Warthin tumor, and extranodal marginal zone B-cell lymphoma are examples of this pathology that are sometimes problematic to differentiate from one another. In this paper the author reviewed the main clinical, pathological and prognostic features of these lesions.
Micropropagation ofAgeratum houstonianumby nodal segments
2017
Ageratum houstonianum is a bedding and flowering potted plant originated from Central America which is generally propagate by seed. In this report a preliminary in vitro technique for propagation of A. houstonianum was investigated. In vitro germinated seeds were used to establish aseptic shoot cultures of several clones. Seedling stem segments bearing 3-4 nodes were placed on Murashige and Skoog (MS) basal medium plus 20 g L-1 sucrose, 8.0 g L-1 Agar to induce axillary shoot development. Axillary shoots were subcultured into the same medium and nodal segments were sectioned and subcultured to increase the stock of shoot cultures. Shoot cultures of the selected clone AG14 were used to accom…
Extranodal extension of nodal metastasis is the main prognostic moderator in squamous cell carcinoma of the esophagus after neoadjuvant chemoradiothe…
2017
Several studies, including comprehensive systematic reviews with meta-analyses of our group of research, have demonstrated the negative prognostic impact of the extranodal extension of nodal metastasis (ENE) in different cancer types, including squamous cell carcinoma (SCC) of the vulva, of the penis and of head and neck, as well as in tumors of the digestive and genitourinary systems, in thyroid cancer and others (1-17).