Search results for "NOSE"

showing 10 items of 1793 documents

Sleep-wake disturbances in patients with amyotrophic lateral sclerosis

2011

Objective To evaluate the frequency, severity and determinants of sleep disturbances in patients with amyotrophic lateral sclerosis (ALS). Methods Information about night-time complaints was collected using a standardised questionnaire, the Pittsburgh Sleep Quality Index (PSQI), and the Epworth Sleepiness Scale (ESS) in a group of 100 patients with ALS and in 100 control subjects matched for age and sex. Functional disability was assessed using the ALS Functional Rating Scale-Revised (ALSFRS-R). Sleep was studied by overnight polysomnography in 12 patients. Results Fifty-nine patients with ALS and 36 controls reported sleep disturbances. The mean global PSQI score of patients with ALS was s…

AdultMaleSleep Wake Disordersmedicine.medical_specialtyNeuromuscular diseasePolysomnographyPolysomnographySeverity of Illness IndexPittsburgh Sleep Quality IndexSurveys and QuestionnairesmedicineHumansNocturiaamyotrophic lateral sclerosis sleep disordersWakefulnessAmyotrophic lateral sclerosisDepression (differential diagnoses)Agedmedicine.diagnostic_testEpworth Sleepiness ScaleAmyotrophic Lateral SclerosisMiddle Agedmedicine.diseaseSleep in non-human animalsPsychiatry and Mental healthCase-Control StudiesPhysical therapyFemaleSurgeryNeurology (clinical)medicine.symptomSleepPsychologyJournal of Neurology, Neurosurgery & Psychiatry
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Association Between Restless Legs Syndrome and Adult ADHD in a German Community-Based Sample

2015

Objective: Previous research in clinical samples indicated a significant association between ADHD and restless legs syndrome (RLS). The present study examined the association between adult ADHD and RLS in the German population. Method: Self-rating instruments to assess RLS, childhood ADHD, and adult ADHD were administered to a community-based sample ( N = 1,632). In addition, current depression and anxiety, sleep disturbances, weight, and height were assessed by self-report. Results: Adult ADHD was associated with statistically significant increases in the odds of meeting diagnostic criteria for RLS even when adjusting for potential confounding variables such as weight (odds ratio [OR] = 3…

AdultMaleSleep Wake Disordersmedicine.medical_specialtyPediatricsAnxietyOdds03 medical and health sciences0302 clinical medicineGermanyRestless Legs Syndromemental disordersPrevalenceDevelopmental and Educational PsychologymedicineHumansRestless legs syndromeAssociation (psychology)PsychiatryDepression (differential diagnoses)Depressive DisorderDepressionConfoundingOdds ratioMiddle Agedmedicine.diseaseConfidence interval030227 psychiatryClinical PsychologyAttention Deficit Disorder with HyperactivityAnxietyFemalemedicine.symptomPsychology030217 neurology & neurosurgeryJournal of Attention Disorders
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Pain and severe sleep disturbance in the general population: Primary data and meta-analysis from 240,820 people across 45 low- and middle-income coun…

2018

Objective:\ud Pain and sleep disturbances are widespread, and are an important cause of a reduced quality of life. Despite this, there is a paucity of multinational population data assessing the association between pain and sleep problems, particularly among low- and middle-income countries (LMICs). Therefore, we investigated the relationship between pain and severe sleep disturbance across 45 LMICs.\ud \ud Method: \ud Community-based data on 240,820 people recruited via the World Health Survey were analyzed. Multivariable logistic regression analyses adjusted for multiple confounders were performed to quantify the association between pain and severe sleep problems in the last 30 days. A me…

AdultMaleSleep Wake Disordersmedicine.medical_specialtySleep Pain Sleep disturbance Psychiatry Low- and middle-income countries*Low- and middle-income countriesPopulationSleep disturbancePainSleep Wake DisordersComorbidityAnxietyGlobal Health03 medical and health sciences*Sleep0302 clinical medicine*PainmedicineInsomniaHumans030212 general & internal medicineeducationDeveloping CountriesDepression (differential diagnoses)Psychiatryeducation.field_of_studySleep disorderLow- and middle-income countriesbusiness.industryDepressionLow- and middle-income countries; Pain; Psychiatry; Sleep; Sleep disturbance; Psychiatry and Mental HealthOdds ratio*Sleep disturbanceMiddle Agedmedicine.diseaseComorbidityHealth SurveysPsychiatry and Mental healthRC0321Physical therapyAnxiety*PsychiatryFemalemedicine.symptomSleepbusiness030217 neurology & neurosurgeryStress PsychologicalGeneral hospital psychiatry
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Sedentary behaviour and sleep problems among 42,489 community-dwelling adults in six low- and middle-income countries

2018

There is a lack of multinational research investigating the association between sleep problems and sedentary behaviour. In this study, we investigated the relationship between the time spent sedentary during waking hours and sleep problems in six low- and middle-income countries. Cross-sectional, community-based data from the Study on Global Ageing and Adult Health survey were analysed. Adjusted logistic regression analyses were undertaken to explore the relationship between self-reported sleep problems (such as difficulties falling asleep, waking up frequently during the night or waking up too early in the morning) in the last 30 days and self-reported sedentary time (categorized as <4,…

AdultMaleSleep Wake DisordersobesityAdolescentCognitive NeuroscienceinsomniaMotor ActivityLogistic regressionSitting03 medical and health sciencesBehavioral NeuroscienceYoung Adult0302 clinical medicineInsomniaMedicineHumans030212 general & internal medicinelow- and middle-income countriesPovertyDepression (differential diagnoses)MorningAgedbusiness.industryDepressionsittingGeneral MedicineMiddle Agedmedicine.diseaseObesityMental healthHealth SurveysConfidence intervalCross-Sectional StudiesFemaleIndependent LivingSelf Reportmedicine.symptomSedentary Behaviorbusiness030217 neurology & neurosurgeryDemography
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Prevalence and correlates of depression during the COVID-19 pandemic and the major role of stigmatization in low- and middle-income countries: A mult…

2021

Highlights • There are significant differences on the prevalence of depression between the four LMICs. • Stigmatization related to COVID-19, but not exposure to COVID-19 was the strongest predictor of depression. • Resilience was a protective factor for DR Congo and Togo. • Younger age, gender (female), and exposure and stigmatization related to Covid-19, and resilience were associated with depression in the pooled data.

AdultMaleSocial stigmaCross-sectional studymedia_common.quotation_subjectSocial StigmaAnxietyStigmatizationArticle03 medical and health sciencesYoung Adult0302 clinical medicineEnvironmental healthPandemicPrevalenceMedicineHumansYoung adultPandemicsPovertyDepression (differential diagnoses)Biological Psychiatrymedia_commonStereotypingPovertyResiliencebusiness.industryDepressionSARS-CoV-2RwandaCOVID-19Middle AgedMental healthDR Congo Haiti Rwanda and TogoHaiti030227 psychiatryPsychiatry and Mental healthCross-Sectional StudiesMental HealthTogoDemocratic Republic of the CongoIncomeEducational StatusFemalePsychological resiliencebusiness030217 neurology & neurosurgeryPsychiatry Research
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Effects of cold atmospheric plasma (CAP) on bacteria and mucosa of the upper aerodigestive tract.

2019

Abstract Objective Ear, nose and throat infections are among the most common reasons for absence from work. They are usually caused by various bacteria like Haemophilus influenzae, Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus pyogenes. Cold atmospheric plasma (CAP) can effectively eliminate even multi-resistant bacteria and has no cytotoxic or mutagenic effects on the mucosa when applied for less than 60 s. Aim of the study was to evaluate the effects of CAP on common ENT bacteria and on the mucosa of the upper aerodigestive tract. Methods The bactericidal effects of CAP against the bacteria most commonly causing ENT infections were investigated using the colony-forming…

AdultMaleStaphylococcus aureusNecrosisPlasma GasesCell SurvivalStreptococcus pyogenesColony Count MicrobialOropharynxRespiratory Mucosamedicine.disease_causeMicrobiologyHaemophilus influenzae03 medical and health sciencesNecrosisYoung Adult0302 clinical medicineOrgan Culture TechniquesStreptococcus pneumoniaeotorhinolaryngologic diseasesmedicineHumansOtitisViability assay030223 otorhinolaryngologyRespiratory Tract InfectionsNoseRhinitisbiologybusiness.industryPharyngitisGeneral MedicineMiddle Agedbiology.organism_classificationHaemophilus influenzae3. Good healthmedicine.anatomical_structureStreptococcus pneumoniaeOtorhinolaryngologyStaphylococcus aureus030220 oncology & carcinogenesisStreptococcus pyogenesSurgeryFemalemedicine.symptombusinessBacteriaAuris, nasus, larynx
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Use of alcohol, drugs, inhalants, and smoking tobacco and the long-term risk of depression in men: A nationwide Swedish cohort study from 1969–2017

2021

Background: The use of alcohol, drugs, inhalants, and smoking tobacco may lead to mood disorders such as depression. However, knowledge on the independent contributions of the use of these substances to the risk of depression is lacking. Methods: The study cohort consisted of 24,564 men included in the Swedish national military conscription register who were conscripted in 1969–1970 and followed until 2017. Cox proportional hazard ratios were used to estimate the risk of depression according to alcohol, drug, inhalant, and cigarette consumption, and adjusted for body mass index, verbal comprehension test scores, handgrip strength, and the other main exposures investigated. Results: During a…

AdultMaleSubstance-Related DisordersToxicologyCohort Studies03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsTobaccoTobacco SmokingMedicineHumansPharmacology (medical)030212 general & internal medicineAlcohol disorderDepression Drug abuse SmokingDepression (differential diagnoses)Proportional Hazards ModelsPharmacologySwedenPsychotropic DrugsHand Strengthbusiness.industryDepressionSmoking TobaccoHazard ratioSmokingTobacco ProductsMiddle Agedmedicine.diseaseSubstance abusePsychiatry and Mental healthMood disordersPharmaceutical PreparationsCohortFemalebusinessBody mass index030217 neurology & neurosurgeryDemographyCohort study
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Mental load during cognitive performance in complex regional pain syndrome I.

2018

Background Complex regional pain syndrome (CRPS) is associated with deficits in limb recognition. The purpose of our study was to determine whether mental load during this task affected performance, sympathetic nervous system activity or pain in CRPS patients. Methods We investigated twenty CRPS‐I patients with pain in the upper extremity and twenty age‐ and sex‐matched healthy controls. Each participant completed a limb recognition task. To experimentally manipulate mental load, the presentation time for each picture varied from 2 s (greatest mental load), 4, 6 to 10 s (least mental load). Before and after each run, pain intensity was assessed. Skin conductance was recorded continuously. R…

AdultMaleSympathetic nervous systemmedicine.medical_specialtySympathetic Nervous SystemEmotionsPainAnxiety03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationCognition030202 anesthesiologyTask Performance and AnalysisMedicineHumansEffects of sleep deprivation on cognitive performanceMental loadYoung adultAssociation (psychology)Depression (differential diagnoses)Agedbusiness.industryDepressionExtremitiesMiddle Agedmedicine.diseaseReflex Sympathetic DystrophyAnesthesiology and Pain Medicinemedicine.anatomical_structureComplex regional pain syndromeAnxietyFemalemedicine.symptombusiness030217 neurology & neurosurgeryEuropean journal of pain (London, England)
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Leukocyte telomere length in mastocytosis: correlations with depression and perceived stress.

2013

Abstract Background Mastocytosisis a rare disease associated with chronic symptoms related to mast cell mediator release. Patients with mastocytosis display high level of negative emotionality such as depression and stress sensibility. Brain mast cells are mainly localized in the diencephalon, which is linked to emotion regulatory systems. Negative emotionality has been shown to be associated with telomere shortening. Taken together these observations led us to hypothesize that mast cells activity could be involved in both negative emotionality and telomere shortening in mastocytosis. Objective To demonstrate a possible relationship between negative emotionality in mastocytosis and leukocyt…

AdultMaleTelomeraseImmunologyPopulationPerceived Stress ScaleDiseaseBehavioral NeuroscienceYoung AdultmedicineHumanseducationDepression (differential diagnoses)Telomere ShorteningAgededucation.field_of_studyEndocrine and Autonomic SystemsDepressionBeck Depression InventoryMiddle AgedMast cellTelomeremedicine.anatomical_structureImmunologyLeukocytes MononuclearFemalePsychologyMastocytosisStress PsychologicalBrain, behavior, and immunity
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Correlations between hormones, physical, and affective parameters in aging urologic outpatients.

2004

Abstract Objective: To determine the relationship between sex hormones, physical complaints, depression, sexuality, and life satisfaction in aging men. Methods: 263 outpatients aged 40 years and above ( M =56.2; 40–84 years) were recruited from 6 andrological outpatient departments in Germany to evaluate "aging male" symptoms. Subjects were assessed by standardised self-report questionnaires, physical, and endocrinological examination. Results: Total and free testosterone as well as DHEA-S (dehydroepiandrosterone-sulfate) levels decreased significantly with age. SHBG (sex hormone binding globulin) and LH (luteinizing hormone) increased; estradiol remained unchanged. Inactivity, lower urinar…

AdultMaleUrologic Diseasesmedicine.medical_specialtyAgingmedicine.drug_classUrologyPhysiologySex hormone-binding globulinLower urinary tract symptomsInternal medicineSurveys and QuestionnairesOutpatientsmedicineHumansGonadal Steroid HormonesDepression (differential diagnoses)AgedAged 80 and overbiologybusiness.industryDepressionTestosterone (patch)Middle AgedAndrogenmedicine.diseaseSexual desireErectile dysfunctionEndocrinologybiology.proteinQuality of LifebusinessLuteinizing hormoneSexualityEuropean urology
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