Search results for "NPR."
showing 10 items of 144 documents
<p>Preoperative Anemia and Iron Deficiency Screening, Evaluation and Management: Barrier Identification and Implementation Strategy Mapping<…
2020
Introduction and aims: Patients undergoing major surgery risk significant blood loss and transfusion, which increases substantially if they have pre-existing anemia. Preoperative Anemia and Iron Deficiency Screening, Evaluation and Management Pathways (PAIDSEM-P) outline recommended blood tests and treatment to optimize patients before surgery. Documented success using PAIDSEM-P to reduce transfusions and improve patient outcomes exists, but the reporting quality of such studies is suboptimal. It remains unclear what implementation strategies best support the implementation of PAIDSEM-P. Method: Maximum variation, purposive sampling was used to recruit a total of 15 partici-pants, including…
The effects of glutamate receptor antagonists on cerebellar granule cell survival and development.
2007
N-Methyl-d-aspartate (NMDA) receptor stimulation promotes neuronal survival and differentiation under both in vitro and in vivo conditions. We studied the effects of various NMDA receptor antagonists acting at different NMDA receptor binding sites and non-NMDA receptor antagonists on the development and survival of cerebellar granule cell (CGC) culture. Only three of the drugs tested induced neurotoxicity-MK-801 (non-competitive NMDA channel blocking antagonist), ifenprodil (an antagonist of the NR2B site and polyamine site of the NMDA receptor) and L-701.324 (full antagonist at glycine site), while CGP-37849 (a competitive NMDA antagonist), (+)-HA-966 (a partial agonist of the glycine site…
The NMDA receptor complex: a promising target for novel antiepileptic strategies.
2001
Antiepileptic drugs (AEDs) cover a broad spectrum of pathological conditions ranging from seizures following congenital or acquired brain disorders to behavioural and psychiatric disorders and recently neuropathic pain. The need for novel antiepileptics raises from the expanding field of indications as well as from the fact, that special seizure types are refractory to common AEDs. In addition, many of the conventional antiepileptic drugs exhibit an unfavourable side-effect profile. Since there is growing evidence, that NMDA receptor activation might play a crucial role in epilepsy, NMDA receptor antagonists have become compounds of interest in preventing and treating seizures. This review …
Viaggi nell’immaginario: il turismo virtuale nel sito UNESCO di Tarragona
2023
Le nuove tecnologie hanno trasformato in modo radicale non solo la geografia come disciplina, ma anche le geografie del mondo. Il digitale ha assunto, infatti, un ruolo di mediazione sempre più pervasivo nella produzione dello spazio, come delle conoscenze e degli immaginari geografici. Le possibilità offerte dal virtuale, in particolare, offrono oggi un contributo decisivo nella comunicazione dei significati attribuiti ai luoghi e rispondono in modo sempre più efficace ai bisogni emergenti del settore turistico. Le esperienze di visita mediate dal digitale mirano a coinvolgere i sensi e risultano efficaci quando promuovono immersioni rigorosamente realistiche. Nel quadro di queste riflessi…
Il Piano nazionale di ripresa e resilienza e le sue fonti: dinamiche dei processi normativi in tempo di crisi
2022
Il libro descrive ed opera un'analisi critica del quadro normativo Euro-nazionale nell'ambito del quale è stato definito il Piano nazionale di ripresa e resilienza italiano (PNRR). Oggetto principale dell'analisi è l'impatto del quadro normativo UE nell'ambito del quale è stato sviluppato Next Generation EU ed, in particolare, il Dispositivo sulla ripresa e la resilienza, sul sistema delle fonti che caratterizza l'ordinamento costituzionale italiano. Sono prese in esame, in particolare le "misure legislative" previste dal piano, il sistema di indicatori di valutazione delle stesse per verificare se è stata data "soddisfacente" attuazione al Piano e le prassi attuative. The book gives an ove…
Dynamics of non-local systems handled by fractional calculus
2007
Mechanical vibrations of non-local systems with long-range, cohesive, interactions between material particles have been studied in this paper by means of fractional calculus. Long-range cohesive forces between material particles have been included in equilibrium equations assuming interaction distance decay with order α . This approach yields as limiting case a partial fractional differential equation of order α involving space-time variables. It has been shown that the proposed model may be obtained by a discrete, mass-spring model that includes non-local interactions by non-adjacent particles and the mechanical vibrations of the particles have been obtained by an approximation fractional …
P26 Early motherhood: a qualitative study exploring experiences of adolescent mothers in the hohoe municipality of ghana
2018
Background Each year between 14 and 15 million adolescent girls give birth, accounting for more than 10% of births globally. Motherhood is an exciting time for every woman and the society at large and also seen as a significant part of any woman’s identity but that is often not the case for the adolescent mother. Adolescent motherhood can be a time of mixed feelings as it occurs at a critical time of their lives. This study examined challenges adolescent mothers face during early motherhood and strategies to improve early motherhood for better social and health outcomes. Methods Based on a phenomenological perspective, this qualitative study was conducted in the Hohoe Municipality where pur…
PENGARUH BEBAN, KOMPENSASI DAN LINGKUNGAN KERJA TERHADAP DISIPLIN KERJA KARYAWAN
2020
This study aims to determine whether the workload, compensation and partial and simultaneous work environment of employee work discipline at PT. Bank Rakyat Indonesia (Persero) Tbk Manokwari Branch Office. 
 This type of research is associative quantitative research. The sample used in this study was 53 respondents with a sampling technique using Nonprobability Sampling. Data collection uses observation, interviews, and questionnaires.
 The results of this study prove that work is significant for employee work discipline, significant compensation for employee work discipline, and work environment significantly affects employee work discipline. Simultaneously the workload, compensa…
How to make head or tail of ‘bridging’ and ‘bonding’?: addressing the methodological ambiguity1
2008
A distinction has recently been proposed between bridging (or encompassing) and bonding (or inward-looking) social networks. However, existing theoretical contributions remain vague as to the fundamental meaning of both concepts. As a consequence, two distinct interpretations have developed alongside each other. In the present paper, we employ data on voluntary association membership in Flanders to empirically illustrate that both approaches can lead to substantially different outcomes and therefore appear to tap into different dimensions of bridging versus bonding. These findings underline the problematic nature of the current conceptual ambiguity. We conclude that should the bridging/bond…