Search results for "NS-2"
showing 10 items of 23 documents
CCDC 245910: Experimental Crystal Structure Determination
2006
Related Article: R.Frohlich, T.C.Rosen, O.G.J.Meyer, K.Rissanen, G.Haufe|2006|J.Mol.Struct.|787|50|doi:10.1016/j.molstruc.2005.10.033
CCDC 222577: Experimental Crystal Structure Determination
2004
Related Article: M.Alajarin, A.Vidal, F.Tovar, M.C.R.de Arellano|2004|Tetrahedron:Asymm.|15|489|doi:10.1016/j.tetasy.2003.11.025
Clostridium difficile Toxins Disrupt Epithelial Barrier Function by Altering Membrane Microdomain Localization of Tight Junction Proteins
2001
ABSTRACT The anaerobic bacterium Clostridium difficile is the etiologic agent of pseudomembranous colitis. C. difficile toxins TcdA and TcdB are UDP-glucosyltransferases that monoglucosylate and thereby inactivate the Rho family of GTPases (W. P. Ciesla, Jr., and D. A. Bobak, J. Biol. Chem. 273:16021–16026, 1998). We utilized purified reference toxins of C. difficile , TcdA-10463 (TcdA) and TcdB-10463 (TcdB), and a model intestinal epithelial cell line to characterize their influence on tight-junction (TJ) organization and hence to analyze the mechanisms by which they contribute to the enhanced paracellular permeability and disease pathophysiology of pseudomembranous colitis. The increase i…
VCD studies on cyclic peptides assembled from L-α-amino acids and a trans-2-aminocyclopentane- or trans-2-aminocyclohexane carboxylic acid.
2010
The increasing interest in peptidomimetics of biological relevance prompted us to synthesize a series of cyclic peptides comprising trans-2-aminocyclohexane carboxylic acid (Achc) or trans-2-aminocyclopentane carboxylic acid (Acpc). NMR experiments in combination with MD calculations were performed to investigate the three-dimensional structure of the cyclic peptides. These data were compared to the conformational information obtained by electronic circular dichroism (ECD) and vibrational circular dichroism (VCD) spectroscopy. Experimental VCD spectra were compared to theoretical VCD spectra computed quantum chemically at B3LYP/6-31G(d) density functional theory (DFT) level. The good agreem…
Zvaigžņotā Debess: 2008, Rudens
2008
Latvijas Zinātņu akadēmija, Latvijas Universitāte
Zvaigžņotā Debess: 60.gadskārta
2019
Contents: In Remembrance of Jānis Ikaunieks, Arturs Balklavs and Andrejs Alksnis: I.Pundure. «ZVAIGŽŅOTĀ DEBESS» Was Leading to the Truth … ; I.Pundure. Astronomers of Latvian Origin in IAU Management ; DISCOVERIES: I.Pundure. Gaia’s Most Accurate Star Map of Milky Way and Its Surroundings ; SPACE RESEARCH and EXPLORATION: I.Pundure. ESA Selects Three New Missions to Explore the Universe ; LATVIAN SCIENTISTS: The List of Popular Science Papers (1958-2016) by Professor Andrejs Alksnis (concluded) ; In memoriam: Dr.sc.ing. Edgars Bervalds (1936-2019) ; In memoriam: Dr.phys. Natālija Cimahoviča (1926-2019) ; FLASHBACK: I.Pundure. On Hawking’s Publication in the Vatican’s Commentarii Series ; F…
CCDC 882133: Experimental Crystal Structure Determination
2012
Related Article: M.V.Leskinen, Kai-Tai Yip, A.Valkonen, P.M.Pihko|2012|J.Am.Chem.Soc.|134|5750|doi:10.1021/ja300684r
CCDC 280350: Experimental Crystal Structure Determination
2006
Related Article: R.Frohlich, T.C.Rosen, O.G.J.Meyer, K.Rissanen, G.Haufe|2006|J.Mol.Struct.|787|50|doi:10.1016/j.molstruc.2005.10.033
CCDC 245916: Experimental Crystal Structure Determination
2006
Related Article: R.Frohlich, T.C.Rosen, O.G.J.Meyer, K.Rissanen, G.Haufe|2006|J.Mol.Struct.|787|50|doi:10.1016/j.molstruc.2005.10.033
CCDC 882134: Experimental Crystal Structure Determination
2012
Related Article: M.V.Leskinen, Kai-Tai Yip, A.Valkonen, P.M.Pihko|2012|J.Am.Chem.Soc.|134|5750|doi:10.1021/ja300684r