Search results for "NTSR"
showing 3 items of 3 documents
Activation of Corticothalamic Layer 6 Cells Decreases Angular Tuning in Mouse Barrel Cortex.
2019
In the mouse whisker system, the contribution of L6 corticothalamic cells (L6 CT) to cortical and thalamic processing of the whisker deflection direction was investigated. A genetically defined population of L6 CT cells project to infragranular GABAergic interneurons that hyperpolarize neurons in somatosensory barrel cortex (BC). Optogenetic activation of these neurons switched BC to an adapted mode in which excitatory cells lost their angular tuning. In contrast, however, this was not the case with a general activation of inhibitory interneurons via optogenetic activation of Gad2-expressing cells. The decrease in angular tuning, when L6 CT cells were activated, was due to changes in cortic…
A transcriptomics-based approach enables the first identification of candidate genes involved in non-target-site-based resistance to herbicides in a …
2013
International audience; Herbicides are the most effective way to control weeds. Yet, the evolution of resistance in many weed species is a considerable threat to herbicide efficacy. Non-target-site-based resistance (NTSR) is the most threatening facet of herbicide resistance. NTSR is widespread, involves a variety of mechanisms, and can confer unpredictable resistance to herbicides, regardless of the herbicide mode of action. Because NTSR is endowed by differences in the expression of a number of genes in resistant and sensitive weed plants, few genes governing NTSR are currently known. This renders NTSR diagnosis and management tricky. The rise of next-generation sequencing technologies no…
Les phytoprotecteurs (« Safeners ») associés aux herbicides jouent-ils un rôle dans la sélection de résistances non liées à la cible ?
2016
Do herbicide-associated "Safeners" play a role in the selection for non-target-site resistances ? To ensure or improve crop selectivity, some herbicide molecules are applied in association with a “safener”. Safeners are compounds that, at the rate applied, enhance herbicide-degrading metabolic pathways supposedly specifically in crop plants. The metabolic pathways enhanced by safeners in crop plants are highly similar to those exacerbated in taxonomically closely related weed species that evolved non-target-site based resistance (NTSR) to herbicides. Herein, we show an enhancing effect of herbicide safeners on NTSR in a major noxious grass weed: rye-grass (Lolium sp.).