Search results for "NUMB"

showing 10 items of 3956 documents

An unsupervised region growing method for 3D image segmentation

1995

The paper deals with 3D shape decomposition problem, objects are modelled as finite unions of almost-convex primitives. A new region growing method is proposed to extract meaningful objects parts. Parts are individuated by performing a set-partitioning of surface dominating points. The partition step returns labelled seeds from which to start a region growing procedure that propagate labels onto object surface patches. A fuzzy concept of λ-convexity is introduced to test noised real images. Experimental results are given.

business.industryRegion growingComputer sciencePartition (number theory)Fuzzy conceptPattern recognitionArtificial intelligenceExtreme pointbusinessReal imageDecomposition problem
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Large-eddy simulations of turbulent flow with heat transfer in simple and complex geometries using Harwell-FLOW3D

1996

Abstract Large-eddy simulation (LES) results are presented and discussed for the turbulent flow with heat transfer in different geometrical configurations, including a plane channel, a channel bearing transverse square ribs on one of the walls, and a crossed-corrugated air heater. They were obtained using the computational fluid dynamics (CFD) code Harwell-FLOW3D (Release 2), finite-volume grids having up to 423 nodes, and the Smagorinsky subgrid model with several variants regarding near-wall damping and wall boundary conditions. The first problem (plane turbulent Poiseuille flow with heat transfer) was mainly used as a benchmark to investigate the influence of numerical methods (pressure-…

business.industryTurbulenceApplied MathematicsPrandtl numberTurbulence modelFluid mechanicsGeometryMechanicsComputational fluid dynamicsHeat TransferHagen–Poiseuille equationLarge Eddy SimulationSubgrid modelPhysics::Fluid Dynamicssymbols.namesakeModelling and SimulationModeling and SimulationHeat transfersymbolsBoundary value problemCFDbusinessSettore ING-IND/19 - Impianti NucleariMathematicsLarge eddy simulationApplied Mathematical Modelling
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Spectrum of novel mutations found in Waardenburg syndrome types 1 and 2: implications for molecular genetic diagnostics

2013

Objectives Till date, mutations in the genes PAX3 and MITF have been described in Waardenburg syndrome (WS), which is clinically characterised by congenital hearing loss and pigmentation anomalies. Our study intended to determine the frequency of mutations and deletions in these genes, to assess the clinical phenotype in detail and to identify rational priorities for molecular genetic diagnostics procedures. Design Prospective analysis. Patients 19 Caucasian patients with typical features of WS underwent stepwise investigation of PAX3 and MITF . When point mutations and small insertions/deletions were excluded by direct sequencing, copy number analysis by multiplex ligation-dependent probe …

business.industryWaardenburg syndromePoint mutationResearch16971689Copy number analysisTietz syndromeGenetics and GenomicsGeneral MedicineGene mutationMicrophthalmia-associated transcription factorBioinformaticsmedicine.diseaseCongenital hearing lossMedicineMissense mutation1506business1719BMJ Open
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Genetic and Molecular Characterization of The Human Osteosarcoma 3AB-OS Cancer Stem Cell Line: A Possible Model For Studying Osteosarcoma Origin and …

2013

Finding new treatments targeting cancer stem cells (CSCs) within a tumor seems to be critical to halt cancer and improve patient survival. Osteosarcoma is an aggressive tumor affecting adolescents, for which there is no second-line chemotherapy. Uncovering new molecular mechanisms underlying the development of osteosarcoma and origin of CSCs is crucial to identify new possible therapeutic strategies. Here, we aimed to characterize genetically and molecularly the human osteosarcoma 3AB-OS CSC line, previously selected from MG63 cells and which proved to have both in vitro and in vivo features of CSCs. Classic cytogenetic studies demonstrated that 3AB-OS cells have hypertriploid karyotype wit…

cancer stem cellsPhysiologyClinical Biochemistrymedicine.disease_causePolymerase Chain ReactionOsteosarcoma cancer stem cellSettore BIO/10 - BiochimicaChromosomes HumanGene Regulatory NetworksCopy-number variationOligonucleotide Array Sequence AnalysisGeneticsComparative Genomic HybridizationOsteosarcomabiologychromosomal aberrationGene Expression Regulation NeoplasticPhenotypemiRNAsNeoplastic Stem CellsOsteosarcomaMitosisBone NeoplasmsHMGA2Cancer stem cellCell Line TumormicroRNABiomarkers Tumorgene expression profilingmedicineHumansOsteosarcoma cancer stem cells; karyotype; chromosomal aberrations; gene expression profiling; miRNAsCell LineageGenetic Predisposition to DiseaseRNA MessengerCell NucleusChromosome AberrationsPloidiesModels GeneticComputational BiologyCancerCell Biologymedicine.diseasekaryotypeMicroRNAsKaryotypingbiology.proteinCancer researchCarcinogenesisComparative genomic hybridization
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An updated catalogue of chromosome numbers in the genus Isoetes L. (Isoetaceae, Lycopodiophyta)

2010

cariology systematics taxonomy chromosome numbers ploidy polyploidy evolution Isoetes Isoetaceae LycopodiophytaSettore BIO/02 - Botanica Sistematica
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Report 1751. Isoetes todaroana Troia & Raimondo. In: Kamari, G., Blanché, C. & Siljak-Yakovlev, S. (eds): Mediterranean chromosome number reports

2011

caryology biosystematics chromosome numberSettore BIO/02 - Botanica Sistematica
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Acid—base properties of azo dyes in the presence of surfactants

1991

Abstract The changes in the acid—base properties of an azo dye produced by the presence of surfactants, at surfactant concentrations below and above the CMC, are quantitatively described using a simple model and spectrophotometric and potentiometric measurements. The azo dye formed by aniline and N -(1-naphthyl)-ethylenediamine, and the surfactants sodium dodecyl sulphate, Triton X-100 and N -cetylpyridinium chloride (NCPC) are used. The protonation constants of the free and surfactant-bound dye species, the binding constant of the protonated and unprotonated forms of the dye, and the average aggregation number of the dye—NCPC aggregates are evaluated.

chemistry.chemical_classificationAggregation numberBase (chemistry)Potentiometric titrationInorganic chemistryProtonationCetylpyridinium chlorideBinding constantSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsBiomaterialschemistry.chemical_compoundColloid and Surface ChemistryAnilinechemistryPulmonary surfactantJournal of Colloid and Interface Science
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Gas phase charged aggregates of bis(2-ethylhexyl)sulfosuccinate (AOT) and divalent metal ions: first evidence of AOT solvated aggregates

2011

Assembling and chelating properties of sodium bis(2-ethylhexyl)sulfosuccinate (AOTNa) towards divalent metal ions have been investigated in the gas phase by electrospray ionization mass spectrometry. A variety of positively charged monometallated and mixed metal aggregates are formed. Interestingly, several ions contain solvent (MeOH, H2O) molecules and constitute the most abundant AOT cationic aggregates not containing sodium. These species are the first example of solvated AOT-metal ion aggregates in the gas phase. By increasing the surfactant aggregation number, the abundance of solvated species becomes lower than that of unsolvated ones. Decompositions of ionic species have been studied…

chemistry.chemical_classificationAggregation numberChemistryElectrospray ionizationInorganic chemistryIonic bondingMoleculePhotochemistryMass spectrometrySpectroscopyAlkylDivalentIonJournal of Mass Spectrometry
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Self-assembly and intra-cluster reactions of erbium and ytterbium bis(2-ethylhexyl)sulfosuccinates in the gas phase

2014

RATIONALE The study of surfactant organization in vacuum allows surfactant–surfactant interaction to be unveiled in the absence of surrounding solvent molecules. Knowledge on their chemical-physical properties may also lead to the definition of more efficient gas-phase carriers, air-cleaning agents and nanoreactors. In addition, the presence of lanthanide-group ions adds unique photochemical properties to surfactants. METHODS The structural features, stability and fragmentation patterns of charged aggregates formed by lanthanide-functionalized surfactants, ytterbium and erbium bis(2-ethylhexyl)sulfosuccinate ((AOT)3Yb and (AOT)3Er), have been investigated by electrospray ionization mass spe…

chemistry.chemical_classificationAggregation numberChemistryElectrospray ionizationOrganic ChemistryAnalytical chemistryMass spectrometryPhotochemistryAnalytical ChemistrySupramolecular assemblyMassFragmentation (mass spectrometry)MoleculeSpectroscopyAlkylRapid Communications in Mass Spectrometry
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Structural organization of surfactant aggregates in vacuo: a molecular dynamics and well-tempered metadynamics study

2015

Experimental investigations using mass spectrometry have established that surfactant molecules are able to form aggregates in the gas phase. However, there is no general consensus on the organization of these aggregates and how it depends on the aggregation number and surfactant molecular structure. In the present paper we investigate the structural organization of some surfactants in vacuo by molecular dynamics and well-tempered metadynamics simulations to widely explore the space of their possible conformations in vacuo. To study how the specific molecular features of such compounds affect their organization, we have considered as paradigmatic surfactants, the anionic single-chain sodium …

chemistry.chemical_classificationAggregation numberChemistryMetadynamicsGeneral Physics and AstronomyIonic bondingmolecular dynamics simulations well-tempered metadynamics simulationsMicellechemistry.chemical_compoundMolecular dynamicsPulmonary surfactantChemical physicsOrganic chemistryPhysical and Theoretical ChemistrySodium dodecyl sulfateAlkylSettore CHIM/02 - Chimica Fisica
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