Search results for "Nanohybrides"
showing 2 items of 2 documents
Elaboration of functionalized nanoparticles : applications as MRI contrast agent
2010
Spinel structured iron oxide nanoparticles open the way of biomedical applications of nanomaterials.Superparamagnetic properties of ten nanometer size crystallites permit to use them in diagnosis such as Magnetic Resonance Imaging (MRI).The aim of this work was to synthesize colloidal suspension of magnetite or maghemite (called USPIO for Ultrasmall SuperParamagnetic Iron Oxide) stable in physiological conditions (pH = 7.4 and [NaCl] = 0.15M).By classical co-precipitation method, UPSIO were synthesized with a mean crystallite size of 8 nm, with a specific surface area of 110 m².g-1 and an aggregate size of 20 nm. To stabilize these nano-objects, two ways were investigated. Electrostatic age…
Iron oxides nanoparticles and titanate nanotubes dedicated to multimodal imaging and anticancer therapy
2013
The new implementations of nanoparticles in the medical field are one of the essential factors of the medical progress expected at the beginning of this XXIst century. Thus, the domain of the medical imaging is also affected by this technological evolution. This work consisted in developing theranostic probes with iron oxides nanoparticles (SPIO) and titanate nanotubes (TiONts) for multimodal imaging (magnetic/nuclear or magnetic/optical) and also possessing a therapeutic effect (hyperthermia/PDT or radiosensitization/PDT).The titanate nanotubes of this study have an average length of about 150 nm and were obtained by Kasuga's hydrothermal synthesis. These nanotubes present an outside diame…