Search results for "Native"

La metacomprensione nei nativi digitali

2012

La tecnologia è progredita anche oltre la nostra capacità d’uso e il lavoro da compiere è quello esplorare i possibili orientamenti didattici per lo sviluppo e la promozione delle abilità di lettura nei ragazzi. L’attenzione alla lettura di testi letterari, informativi, normativi, istruttivi, su supporto cartaceo, dovrebbe essere equilibrata da quella per la lettura di testi digitali, di testi in cui il valore delle parole, accostate a immagini e suoni o rese esse stesse immagine e suono, si dispiegano in un inedito contesto multimediale. Una delle difficoltà che sovente gli insegnanti riscontrano negli allievi, di qualsiasi ordine e grado scolastico, attiene alla loro capacità di comprende…

Gender, Age, and Generational Differences in the Use Intention of Mobile Payments and Its Antecedents

2022

Although mobile payments have gained considerable attention in academic research, there still are major gaps in our more in-depth understanding of the antecedents of their acceptance and use. In this study, we aim to address these gaps by examining the potential gender and age differences in the use intention of mobile payments and its antecedents in terms of the effects of the antecedent factors on use intention as well as the antecedent factors and use intention themselves while also considering the critical prerequisite of measurement invariance. Moreover, through a careful selection of the compared age groups, we extend the examination to cover also the potential generational difference…

Monilukutaidon opetus on ennen kaikkea uusien kirjoitustaitojen opetusta

2014

Täysipainoinen osallistuminen tulevaisuuden yhteiskuntaan vaatii paljon laajempia kirjoitustaitoja kuin koulun kirjoittamisen opetus tällä hetkellä tarjoaa. Uusiin opetussuunnitelmiin tuleva monilukutaito voi tarjota väylän näiden uusien kirjoitustaitojen opiskeluun, mikäli aktiiviseen osallistumiseen ja luovaan sisällöntuotantoon ohjaavat uudet kirjoitustaidot nostetaan tasaveroisesti uusien lukutaitojen rinnalle. Uudistuksella on kuitenkin jo kiire, sillä oppilaat elävät vapaa-ajalla pitkälti jo uusien kirjoitustaitovaatimusten keskellä. nonPeerReviewed

(...) dass man sich traut, zu versuchen : Erfahrungen von Lernern und Lehrern mit einem Native-speaker als Assistenzlehrer in der gymnasialen Oberstu…

2001

Standardisation of methods for assessing mould germination: a workshop report.

2006

International audience; The first workshop on predictive mycology was held in Marseille, France, 2–4 February 2005 under the auspices of the French Microbiological Society. The purpose of the workshop was to list the different techniques and definitions used by scientists for assessing mould germination and to evaluate the influence of the different techniques on the experimental results. Recommendations were made when a large consensus was obtained. In order to facilitate the study of germination, alternative methods to microscopic examination were examined.

Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development.

2015

International audience; Myotonic dystrophy type 1 (DM1) is caused by an unstable expanded CTG repeat located within the DMPK gene 3'UTR. The nature, severity and age at onset of DM1 symptoms are very variable in patients. Different forms of the disease are described, among which the congenital form (CDM) is the most severe. Molecular mechanisms of DM1 are well characterized for the adult form and involve accumulation of mutant DMPK RNA forming foci in the nucleus. These RNA foci sequester proteins from the MBNL family and deregulate CELF proteins. These proteins are involved in many cellular mechanisms such as alternative splicing, transcriptional, translational and post-translational regul…

Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model

2012

SummaryMyotonic dystrophy type 1 (DM1) is a genetic disease caused by the pathological expansion of a CTG trinucleotide repeat in the 3' UTR of the DMPK gene. In the DMPK transcripts, the CUG expansions sequester RNA-binding proteins into nuclear foci, including transcription factors and alternative splicing regulators such as MBNL1. MBNL1 sequestration has been associated with key features of DM1. However, the basis behind a number of molecular and histological alterations in DM1 remain unclear. To help identify new pathogenic components of the disease, we carried out a genetic screen using a Drosophila model of DM1 that expresses 480 interrupted CTG repeats, i(CTG)480, and a collection of…

Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene

2008

Myotonic Dystrophy type 1 (DM1) is a multi-system disorder characterized by muscle wasting, myotonia, cardiac conduction defects, cataracts, and neuropsychological dysfunction. DM1 is caused by expansion of a CTG repeat in the 3 untranslated region (UTR) of the Dystrophia Myotonica Protein Kinase (DMPK) gene. A body of work demonstrates that DMPK mRNAs containing abnormally expanded CUG repeats are toxic to several cell types. A core mechanism underlying symptoms of DM1 is that mutant DMPK RNA interferes with the developmentally regulated alternative splicing of defined pre-mRNAs. Expanded CUG repeats fold into ds(CUG) hairpins that sequester nuclear proteins including human Muscleblind-lik…

Acupuncture in the treatment of temporomandibular disorders, facial pain, and postural neuromuscular disorders. Presentation of a clinical case

2021

Abstract Background and objectives Temporomandibular disorders have a multifactorial etiology and involve the masticatory muscles, temporomandibular joint and associated structures. Therefore, different treatments are proposed and used. The aim of this paper is the use of acupuncture to treat temporomandibular disorders and associated symptoms. This article presents a clinical case study of a 39-year-old patient who presented temporomandibular disorders and headache of muscular origin. Results After 10 acupuncture sessions, the results were highly satisfactory, with complete relief of headache pain and absence of joint disorders. These results suggest the efficacy of acupuncture in the symp…

Rhythmic exercises as tools for rehabilitation following cerebellar stroke: A case study integrating music therapy and physiotherapy techniques

2022

Introduction: This article explores the use of music and multisensory stimuli in the construction of compensatory neural networks for motoric functioning in a patient recovering from cerebellar strokes (CS). This study aimed to address the real-world clinical concern of patients having a passive role in therapy, by arousing the client’s interest and self-motivation in rehabilitation. Method: The article presents a case study of a CS survivor, using data derived from rehabilitation sessions combining music therapy techniques with physiotherapy techniques to improve the fluency and accuracy of his motor performance. Qualitative and quantitative data are used to identify, describe, and evaluat…