Search results for "Native"
showing 10 items of 1727 documents
Neuroprotective potential of Ginkgo biloba in retinal diseases
2019
AbstractLike other tissues of the central nervous system, the retina is susceptible to damage by oxidative processes that result in several neurodegenerative disease such as age-related macular degeneration, diabetic retinopathy, glaucoma, ischaemic retinal disease, retinal disease produced by light oxidation, and detached retina, among other diseases. The use of antioxidant substances is a solution to some health problems caused by oxidative stress, because they regulate redox homeostasis and reduce oxidative stress. This is important for neurodegeneration linked to oxidation processes. In line with this, Ginkgo biloba is a medicinal plant with excellent antioxidant properties whose effect…
Native-state pea albumin and globulin behavior upon transglutaminase treatment
2015
International audience; The behavior of pea albumin (Alb) and globulin (Glob) in their native state upon microbial transglutaminase (MTGase) treatment was studied. Only Glob was able to form a gel, at up to a 10% (w/w) concentration, with a minimum gelling concentration of 6% (w/w), and with a cross-linking degree of 25%. The most affected Glob subunits were convicilin (71 kDa), vicilins (55, 50, and 35 kDa), and legumin acidic subunit (40 kDa). In contrast, the legumin basic subunit (20 kDa) and vicilins of molecular weight less than 20 kDa remained mostly intact in all studied conditions. The cross-linking degree of Alb was 12%, which was not sufficient to form MTGase-induced gel. Major a…
Local dynamic properties of the heme pocket in native and solvent-induced molten-globule-like states of cytochrome c
2002
We report the Soret absorption band, down to cryogenic temperature, of native and molten-globule-like state of horse heart cytochrome c. The band profile is analyzed in terms of vibronic coupling of the heme normal modes to the electronic transition in the framework of the Franck-Condon approximation. From the temperature dependence of the Gaussian broadening and of the peak position, we obtain information on the 'bath' of low frequency harmonic motions of the heme group within the heme pocket. The reported data indicate that, compared to the native state, the less rigid tertiary structure of the molten globule is reflected in a higher flexibility of the heme pocket and in greater conformat…
Styryl-lactones from Goniothalamus species— A review
1999
Thirty-one bioactive styryl-lactones, with six different basic skeletons, have been isolated from Goniothalamus species. Aspects of their isolation, structural elucidation, biogenesis and biological activity are reviewed. Copyright © 1999 John Wiley & Sons, Ltd.
Present participles in the new Gothic palimpsest
2015
A new Gothic text has recently been discovered and it is contained in a palimpsest bifolium of the Archive of the Board of Trustees of San Petronio’s Basilica in Bologna. Two scholars of Milan, R. Bianca Finazzi and Paola Tornaghi, have studied the palimpsest. The author received their paper directly from the two colleagues, who had received word of the interest the discovery of the new Gothic text had kindled in him. In his examination of the text, the author was able to find two cases confirming and one supplementing what he had written in Melazzo (1992) about the two different Gothic forms of the nominative singular of the present participle in the masculine, of which one ends in -ndaand…
Los toques de queda, confinamientos territoriales, prohibiciones de pequeñas reuniones y de actividades y horarios en la contención del Covid-19
2021
Se analizan los “toques de queda”, los confinamientos territoriales o perimetrales, las prohibiciones de pequeñas reuniones, así como las restricciones de actividades y horarios de los establecimientos y sus dudosas garantías. Todas estas restricciones Covid-19 bajo los estados de alarma o el muy cuestionable artículo 3 Ley Orgánica 3/1986 no han sido especial objeto de atención, ha habido fuertes divergencias entre tribunales y están pendientes recursos y cuestiones de constitucionalidad. Se afirman lineamientos y criterios para una deseable futura regulación. Finalmente se concluye que especialmente el gobierno y el legislador estatal no han superado el "test de estrés" al sistema jurídi…
Análisis de las calificaciones compartidas en la modalidad participativa de la evaluación colaborativa entre docente y estudiantes
2020
Current trends in educational assessment in different branches of higher education share the common goal of uniting learning with assessment. Most approaches and theoretical and practical developments in this field revolve around four main factors: feedback, democratization, alignment and relevance. This paper proposes the use of co-assessment as a means of ensuring dialogue-based, democratic and fairer evaluations. With co-assessment, the responsibility is shared by the teacher and the students, who negotiate and agree on the appraisal of student tasks and, in this paper, also on the awarded mark. The aim of this study is to analyse the relationship between a series of jointly agreed marks…
Chemical composition and biological activity of Salvia verbenaca essential oil
2011
Salvia verbenaca L. (syn. S. minore) is a perennial herb known in the traditional medicine of Sicily as “spaccapetri” and is used to resolve cases of kidney stones, chewing the fresh leaves or in decoction. The chemical composition of the essential oil obtained from aerial parts of S. verbenaca collected in Piano Battaglia (Sicily) on July 2009, was analyzed by GC and GC-MS. The oil was strongly characterized by fatty acids (39.5%) and carbonylic compounds (21.2%), with hexadecanoic acid (23.1%), ( Z)-9-octadecenoic acid (11.1%) and benzaldehyde (7.3%) as the main constituents. The in vitro activity of the essential oil against some microorganisms in comparison with chloramphenicol by the …
DEEP EUTECTIC SOLVENTS E LIQUIDI IONICI: SOLVENTI PER LO SVILUPPO DI PROCESSI ECO-COMPATIBILI
2020
L’obiettivo di questi tre anni di Dottorato è stato lo studio e l’utilizzo nuovi solventi di reazione in grado di sostituire i solventi organici classici. In particolare sono stati studiati i Deep Eutectic Solvent (DES) e le miscele di Liquidi Ionici (IL). I DES sono stati utilizzati come solventi per lo studio di reazioni organiche, usate per la formazione di nuovi legami C-C. Nello specifico sono state studiate la reazione di Diels-Alder, e diverse reazioni di coupling C-C catalizzate da Pd. In seguito, i DES sono stati utilizzati per la formazione di nuovi gel supramolecolari, chiamati eutectogel. Questi gel sono stati formati usando come gelator amminoacidi naturali, consentendo quindi …
Texture analysis for infarcted myocardium detection on delayed enhancement MRI
2017
Detection of infarcted myocardium in the left ventricle is achieved with delayed enhancement magnetic resonance imaging (DE-MRI). However, manual segmentation is tedious and prone to variability. We studied three texture analysis methods (run-length matrix, co-occurrence matrix, and autoregressive model) in combination with histogram features to characterize the infarcted myocardium. We evaluated 10 patients with chronic infarction to select the most discriminative features and to train a support vector machine (SVM) classifier. The classifier model was then used to segment five human hearts from the STACOM DE-MRI challenge at MICCAI 2012. The Dice coefficient was used to compare the segmen…