Search results for "Neet"
showing 10 items of 1432 documents
Mitochondrial DNA variation of Drosophila obscura (Diptera: Drosophilidae) across Europe
2022
Drosophila obscura is a common fruit fly that inhabits the temperate forests of Europe. While it is abundant in the north compared to other Drosophila, its density decreases southwards, where it is gradually replaced by other Drosophila species. This study describes variation in the mitochondrial Cyt b gene of D. obscura from several European populations. We observed a large number of haplotypes, together with the structuring of genetic variation. Genetic variation is higher in the west where O1 and related divergent haplotypes dominate. In the east, the O2 haplotype is most frequent, together with haplotypes that recently arose from it. In the central part of the species range, both O1 and…
The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network
2021
AbstractTo investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This cross-sectional study includes 1558 individuals from the Helsinki Birth Cohort Study. Between 2001 and 2004, the Short Form-36 questionnaire was employed to assess mental and physical components of HRQoL and Beck Depression Inventory (BDI) to assess depressive symptoms. Depressive symptoms were categorized into minimal (BDI < 10), non-melancholic and melancholic types of depression. The ePRS-IRs were calculated for the hippocampal (hePRS-IR) and the mesocorticolim…
Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia : a randomized controlled study
2018
Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0-100mm), and functional status was assessed by the Fibromyalgia Impact Questio…
Alaraajojen luun mineraalipitoisuuden ja polven nivelruston väliset yhteydet postmenopausaalisilla naisilla
2011
Tämän poikkileikkaustutkimuksen tarkoituksena oli selvittää luuston (reisiluun kaula, lanneranka L2-L4) mineraalitiheysarvojen ja polven nivelruston (reisiluu, sääriluu) eheyttä kuvaavien dGEMRIC-arvojen välistä yhteyttä postmenopausaalisilla naisilla. Tutkimukseen rekrytoitiin 82 naista (keskimääräiseltä iältään 57,7 vuotta, SD 4,2) lehti-ilmoituksen perusteella. Sisäänottokriteerinä oli rtg:llä arvioidun Kellgren-Lawrence-luokituksen (K/L) mukaan ensimmäisen (K/L1) tai toisen (K/L2) asteen lievä polven nivelrikko. Reisiluun kaulan ja lannerangan (L2–L4) BMC-arvot mitattiin DXA-laitteistolla. Tutkimushenkilöillä ei ollut osteoporoosia, jonka kynnysarvona käytettiin T-arvoa >2,5. Tibian ja …
Quadrupole deformation of Xe-130 measured in a Coulomb-excitation experiment
2020
Physical review / C 102(5), 054304 (2020). doi:10.1103/PhysRevC.102.054304
A fugacity model assessment of ibuprofen, diclofenac, carbamazepine, and their transformation product concentrations in an aquatic environment
2018
An updated version of FATEMOD, a multimedia fugacity model for environmental fate of organic chemicals, was set up to assess environmental behaviour of three pharmaceuticals in northern Lake Päijänne, Finland. Concentrations of ibuprofen, diclofenac, and carbamazepine were estimated at various depths at two sites: near a wastewater treatment plant and 3.5 km downstream the plant. When compared with environmental sampling data from corresponding depths and sites, the predicted concentrations, ranging from nanograms to hundreds of nanograms per litre, were found to be in good agreement. Weather data were utilised with the model to rationalise the effects of various environmental parameters on…
Interplay of spin-dependent delocalization and magnetic anisotropy in the ground and excited states of [Gd2@C78]− and [Gd2@C80]−
2017
The magnetic properties and electronic structure of the ground and excited states of two recently characterized endohedral metallo-fullerenes, [Gd2@C78]- (1) and [Gd2@C80]- (2), have been studied by theoretical methods. The systems can be considered as [Gd2]5+ dimers encapsulated in a fullerene cage with the fifteen unpaired electrons ferromagnetically coupled into an S = 15/2 high-spin configuration in the ground state. The microscopic mechanisms governing the Gd-Gd interactions leading to the ferromagnetic ground state are examined by a combination of density functional and ab initio calculations and the full energy spectrum of the ground and lowest excited states is constructed by means …
Unraveling the interaction between doxorubicin and DNA origami nanostructures for customizable chemotherapeutic drug release
2021
We thank Dr H. Häkkänen for technical assistance and S. Julin for the 24HB DNA origami design. We acknowledge the provision of facilities and technical support by Aalto University Bioeconomy Facilities and OtaNano – Nanomicroscopy Center (Aalto-NMC). The research was carried out under the Academy of Finland Centres of Excellence Programme (2014–2019). Academy of Finland [308578 to M.A.K.]; Deutsche Forschungsgemeinschaft [Emmy Noether Programme to A.H.-J., SFB1032 (Project A06) to T.L.]; Emil Aaltonen Foundation [to H.I. and V.L.]; Jane and Aatos Erkko Foundation [to J.A.I. and V.L.]; Sigrid Jusélius Foundation [to V.L.]; Vilho, Yrjö and Kalle Väisälä Foundation of the Finnish Academy of Sc…
Which direction should I go? A quest for understanding the effect of TMS stimulus orientation on evoked responses
2023
The orientation of the electric field (E-field) induced by transcranial magnetic stimulation (TMS) plays a significant role in determining the magnitude of motor evoked potentials (MEP) and TMS-evoked potentials (TEP). However, fundamental mechanisms explaining the interaction of the induced E-field and the underlying neuronal populations are still largely unknown. We recently entered a quest to understand and describe neurophysiological and physical factors affecting the effect of the E-field orientation on the MEP and TEP. We developed a dual-coil TMS transducer capable of fast and accurate electronic control of the induced E-field orientation. With this transducer, we could scan the effe…