Search results for "Neogene"
showing 10 items of 109 documents
Chemokine Expression Is Involved in the Vascular Neogenesis of Ewing Sarcoma: A Preliminary Analysis of the Early Stages of Angiogenesis in a Xenogra…
2018
Background Ewing sarcoma (EWS) is the second most common bone cancer in pediatric patients. Angiogenesis is a major factor for tumor growth and metastasis. Our aim was to carry out a histological, immunohistochemical, and molecular characterization of the neovascularization established between xenotransplanted tumors and the host during the initial phases of growth in nude mice in three angiogenesis experiments (ES2, ES3, and ES4). Methods The original human EWS were implanted subcutaneously on the backs of three nude mice. Tumor pieces 3 mm–4 mm in size from early passages of Nu432, Nu495, and Nu471 were also implanted subcutaneously on the backs of three sets (ES2, ES3, and ES4) of athymi…
Pathway network inference from gene expression data
2014
[EN] Background: The development of high-throughput omics technologies enabled genome-wide measurements of the activity of cellular elements and provides the analytical resources for the progress of the Systems Biology discipline. Analysis and interpretation of gene expression data has evolved from the gene to the pathway and interaction level, i.e. from the detection of differentially expressed genes, to the establishment of gene interaction networks and the identification of enriched functional categories. Still, the understanding of biological systems requires a further level of analysis that addresses the characterization of the interaction between functional modules. Results: We presen…
Evolutionary trends in arvicolids and the endemic murid Mikrotia - New data and a critical overview
2014
Abstract The study of evolutionary rates dates back to the work of Simpson and Haldane in the 1940s. Small mammals, especially Plio-Pleistocene arvicolids (voles and lemmings), are particularly suited for such studies because they have an unusually complete fossil record and exhibit significant evolutionary change through time. In recent decades, arvicolids have been the focus of intensive research devoted to the tempo and mode of evolutionary change and the identification of trends in dental evolution that can be used to correlate and date fossil sites. These studies have raised interesting questions about whether voles and lemmings had unique evolutionary trajectories, or show convergent …
Factors affecting the distribution of recent lacustrine ostracoda from the Caicedo de Yuso-Arreo Lake (Western Ebro Basin, Spain)
2005
Recent Ostracoda assemblages of the Caicedo de Yuso Lake have been described as representative of palustrine/lacustrine environments in Iberian temperate lakes. This study considers the changes in assemblages at a fixed station during two consecutive annual cycles, as well as their distribution in summer and winter profiles of the lake. Total sample-assemblages have been quantified as species diversities, measured by the Shannon-Wiener index H (S). The trends of this index are compared to physical parameters (temperature, conductivity, dissolved oxygen, CO2) of the bottom waters of this lake. The Ostracoda assemblages (8100 adults and juvenile living specimens, belonging to 20 species) are …
Paleodiversity of the Superfamily Ursoidea (Carnivora, Mammalia) in the Spanish Neogene, related to environmental changes
2014
In the present study we analyse the diversity of the Superfamily Ursoidea during the Neogene of the Iberian Peninsula to further compare it with that of the Neogene of Western Europe to find the different associations of this group. The results indicate that both the diversity and the taxonomy amongst these two regions show important variations, thus letting their interpretation in terms of climatic differentiation. We might relate variations in the abundance of the Ursoidea to the environmental fluctuations taking place during the Miocene and Pliocene. Therefore, they could enable us to reach the assessment of these biogeographical distributions in order to deduce the preferential niches o…
Identification problems of arid environments in the Neogene–Quaternary mammal record of Spain
2006
Abstract In this work, we investigate if broadly used methodologies are adequate to detect periods of aridity based on the Spanish fossil record and try to infer which of them were more or less severe. Thus, we present a qualitative statistical approach to two popular palaeoecological methodologies: ecological diversity and cenograms. Discriminant models, derived from modern localities of known biome, determined the probable biomes of Neogene–Quaternary fossil assemblages. Principal component analyses (PCA) provided additional inference on their ordination within an aridity gradient. While models work adequately with modern faunas, the analyses of the palaeocommunities showed that their eco…
High-speed duetting - latency times of the female acoustic response within the bush-cricket genera
2018
Abstract To find a mate, male and female bush-crickets of the family Phaneropteridae typically engage in duets. The male sings and the female responds. For mutual recognition, the amplitude pattern of the male song and the species-specific timing of the female response have been shown to be very important. In the seven studied species, belonging to the genera Leptophyes and Andreiniimon, these duets are extremely fast and nearly completely in the ultrasonic range. The females produce very short sounds by fast closing movements of the tegmina. They respond with species-specific delays of 20 to 150 ms after the beginning of the male song. The different latency times are probably not important…
The architecture and Neogene to Recent evolution of the W Calabrian continental margin: an upper plate perspective to the Ionian subduction system (C…
2010
The western Calabria continental margin forms the transition between the Pliocene to Recent Marsili spreading center and continental Calabria, all parts of the upper plate of the Ionian subduction zone. Integrating high-resolution and crustal seismic images constrained by gravity modeling, we provide a detailed reconstruction of the architecture of the margin and develop a new scheme for its Miocene to present evolution. This time span encompasses the continent-continent collision between Africa and Eurasia, subsequent orogenic collapse and rifting apart between the two continental masses, and the Pliocene to Recent emplacement of oceanic crust in the Vavilov and Marsili basins. The crust o…
Fauna Europaea: Hymenoptera - Apocrita (excl. Ichneumonoidea)
2015
Fauna Europaea provides a public web-service with an index of scientific names (including important synonyms) of all living European land and freshwater animals, their geographical distribution at country level (up to the Urals, excluding the Caucasus region), and some additional information. The Fauna Europaea project covers about 230,000 taxonomic names, including 130,000 accepted species and 14,000 accepted subspecies. This represents a huge effort by more than 400 contributing specialists throughout Europe and is a unique (standard) reference suitable for many users in science, government, industry, nature conservation and education. Hymenoptera is one of the four largest orders of inse…
PESI - a taxonomic backbone for Europe
2015
Reliable taxonomy underpins communication in all of biology, not least nature conservation and sustainable use of ecosystem resources. The flexibility of taxonomic interpretations, however, presents a serious challenge for end-users of taxonomic concepts. Users need standardised and continuously harmonised taxonomic reference systems, as well as highquality and complete taxonomic data sets, but these are generally lacking for nonspecialists. The solution is in dynamic, expertly curated web-based taxonomic tools. The Pan-European Species-directories Infrastructure (PESI) worked to solve this key issue by providing a taxonomic e-infrastructure for Europe. It strengthened the relevant social (…