Search results for "Neurobiologia"
showing 9 items of 19 documents
Editorial: New Insights Into Adult Neurogenesis and Neurodegeneration: Challenges for Brain Repair.
2022
The formation of new neurons in the brain is probably one of the most controversial topics in the scientific community since in the 1960's Joseph Altman described for the first time that proliferating cells give rise to new neurons in the adult brain of rats and other mammals. This Research Topic includes 1 brief research report, 3 mini review, 4 review and 9 original research papers gathering different contributions highlighting new developments in the field of neurogenesis.
Prenatal Omega-6:Omega-3 Ratio and Attention Deficit and Hyperactivity Disorder Symptoms
2019
Supported by the Spanish Institute of Health Carlos III (Co-funded by European Regional Development Fund “A way to make Europe”) (CP14/00108, PI16/00261, MS14/00108 [to J.J.]), the Agència de Gestió d’Ajuts Universitaris i de Recerca, Generalitat de Catalunya - Fons Social Europeu (2017 FI_B 00636 [to N.V-T.]), the Spanish Ministry of Science and Innovation (RYC-2012-10995 [to P.D.] and RYC-2011-08796 [to D.R.]), Obra Social Cajastur/Fundación Liberbank, Universidad de Oviedo, CIBERESP, Department of Health of the Basque Government, the Provincial Government of Gipuzkoa, the municipalities of the study area (Zumarraga, Urretxu, Legazpi, Azkoitia y Azpeitia y Beasain), Generalitat Valenciana…
Irradiation of the head reduces adult hippocampal neurogenesis and impairs spatial memory, but leaves overall health intact in rats.
2021
Treatment of brain cancer, glioma, can cause cognitive impairment as a side‐effect, possibly because it disrupts the integrity of the hippocampus, a structure vital for normal memory. Radiotherapy is commonly used to treat glioma, but the effects of irradiation on the brain are still poorly understood, and other biological effects have not been extensively studied. Here we exposed healthy adult male rats to small and moderate‐dose irradiation of the head. We found no effect of irradiation on systemic inflammation, weight gain or gut microbiota diversity, although it increased the abundance of Bacteroidaceae family, namely Bacteroides genus in the gut microbiota. Irradiation had no effect on…
Addiction. Aspetti biologici e di ricerca
2010
Negli ultimi anni lo studio delle dipendenze patologiche si è arricchito di numerosi contributi scientifici ma anche di osservazioni cliniche che hanno ampliato l'area di indagine sulle condotte compulsive. Obiettivo degli autori è offrire le acquisizioni più recenti per affrontare la sfida che le dipendenze patologiche pongono oggi al clinico e al ricercatore, allo psicofarmacologo e allo psicoterapeuta
Temes 2, 3 i 4 de Neurobiologia, Grau de Biologia
2012
Neurotrofines, sinaptogènesi, supervivència i mort neuronal. Paper en el desenvolupament, la degeneració i en la neurotoxicitat. El con de creixement axònic. Estructura i funció neuronal. Estructura de la neurona i la sinapsi. La glia: Paper en el desenvolupament del sistema nerviós, la funció neural i la neurodegeneració. La presentació forma part dels materials docents programats mitjançant l'ajut del Servei de Política Lingüística de la Universitat de València.
Community detection‐based deep neural network architectures: A fully automated framework based on Likert‐scale data.
2020
Deep neural networks (DNNs) have emerged as a state‐of‐the‐art tool in very different research fields due to its adaptive power to the decision space since they do not presuppose any linear relationship between data. Some of the main disadvantages of these trending models are that the choice of the network underlying architecture profoundly influences the performance of the model and that the architecture design requires prior knowledge of the field of study. The use of questionnaires is hugely extended in social/behavioral sciences. The main contribution of this work is to automate the process of a DNN architecture design by using an agglomerative hierarchical algorithm that mimics the con…
Evaluación del efecto de duloxetina y pregabalina en un modelo de fibromialgia inducida por reserpina en rata
2017
INTRODUCCIÓN El síndrome de fibromialgia (FMS) es una enfermedad que se caracteriza principalmente por dolor muscular crónico generalizado o multifocal de origen desconocido, y la co-existencia de otras manifestaciones clínicas, como las alteraciones del estado de ánimo, los trastornos del sueño, la fatiga, la rigidez matutina, las disfunciones cognitivas, la ansiedad, los dolores de cabeza recurrentes, los mareos, el síndrome de colon irritable y/o el dolor urogenital. La alta prevalencia de este síndrome en la población general plantea un problema social y económico, además, la complejidad de su diagnóstico y la falta de eficacia y efectividad de los tratamientos farmacológicos evidencia …
The adult spinal cord harbors a population of GFAP-positive progenitors with limited self-renewal potential
2013
Adult neural stem cells (aNSCs) of the forebrain are GFAP-expressing cells that are intercalated within ependymal cells of the subventricular zone (SVZ). Cells showing NSCs characteristics in vitro can also be isolated from the periaqueductal region in the adult spinal cord (SC), but contradicting results exist concerning their glial versus ependymal identity. We used an induci- ble transgenic mouse line (hGFAP-CreERT2) to conditionally label GFAP-expressing cells in the adult SVZ and SC periaque- duct, and directly and systematically compared their self-renewal and multipotential properties in vitro. We demonstrate that a population of GFAP1 cells that share the morphology and the antigeni…
Rol de les xarxes perineuronals en la plasticitat d'interneurones de l'escorça cerebral adulta
2018
L’esquizofrènia és un trastorn psiquiàtric complex que afecta a aproximadament el 1% de la població mundial. Tot i que els mecanismes etiopatològics exactes romanen sense esclarir, un recent cos d’evidències apunta a la possible implicació de les xarxes perineuronals, uns agregats especialitzats de la matriu extracel·lular presents en el neocòrtex de mamífers. La formació de les xarxes perineuronals durant el desenvolupament postnatal, el seu possible paper en el control de la plasticitat sinàptica i la seva co-localització amb diferents poblacions neuronals GABAèrgiques que expressen parvalbúmina, suggereixen que l’alteració d’aquestes estructures podria trencar el balanç d’excitació/inhib…