Search results for "Neurologi"

Methylprednisolone-induced hepatotoxicity in a 16-year-old girl with multiple sclerosis.

2018

Multiple sclerosis (MS) is a chronic inflammatory disease with demyelination of the central nervous system. High-dosage corticosteroids are the first-line therapy in the acute relapsing of MS. We report a case of severe high-dose methylprednisolone-induced acute hepatitis in a patient with a new diagnosis of MS. A 16-year-old girl was admitted for urticaria, angioedema, nausea and vomiting a month later she had been diagnosed with MS and treated with high-dosage methylprednisolone. Laboratory investigations showed hepatic insufficiency with grossly elevated liver enzymes. A liver biopsy showed focal centrilobular hepatocyte necrosis with interface hepatitis. Methylprednisolone-induced hepat…

SPORADIC PARKINSON DISEASE AND AMYOTROPHIC LATERAL SCLEROSIS COMPLEX (BRAIT-FAHN-SCHWARTZ DISEASE).

2013

Planning and executing sequential motor acts in Parkinson Disease

1997

Many experimental evidences highlighted that Parkinson Disease (PD) patients are particularly impaired in performing a sequence of movements. In the present experiment we focused to study how PD patients plan and execute an action constituted by the sequence of reaching-grasping an object (first motor act) and placing it on a second target (second motor act). We wished to determine whether properties of the target of the second motor act influenced the kinematics of first motor act. The results showed that PD patients modified, as the controls, the initial ballistic phase of reaching according to variation of second target position (object extrinsic properties). In particular, peak accelera…

Valutazione della sonnolenza diurna e dei disturbi del sonno in una popolazione di pazienti epilettici

2011

Clinical features and disease out come in patients with pediatric and young adult onset Multiple Sclerosis

2012

EMERGING ROLE OF ULTRASOUND IMAGING ASSOCIATED TO CLINICAL NEUROPHYSIOLOGY AS A SUPPLEMENTARY DIAGNOSTICS TECHNIQUE OF PERIPHERAL NERVES PATHOLOGIES:…

2013

PURPOSE: to show the relevance of peripheral nerve ultrasound imaging as a supplementary technique in a clinical neurophysiological evaluation. METHODS: peripheral nerves ultrasound (US) examination was performed in patients with a medical history of nerve entrapment and/or post-traumatic neuropathy but with clinical or neurophysiological unusual findings. A 10-18 MHz transducer was used. RESULTS: we recruited 50 patients with clinical evidence of peripheral neuropathies (25M, 25F): 24 median nerves, 1 anterior interosseous, 14 ulnar, 3 brachial plexus, 2 posterior interosseus, 1 superficial radial, 1 superficial peroneal and 4 common peroneal nerves. Overall 20/50 patients had a history of…

A Systematic Review of International Clinical Guidelines for Rehabilitation of People With Neurological Conditions: What Recommendations Are Made for…

2019

Background: Upper limb impairment is a common problem for people with neurological disabilities, affecting activity, performance, quality of life, and independence. Accurate, timely assessments are required for effective rehabilitation, and development of novel interventions. International consensus on upper limb assessment is needed to make research findings more meaningful, provide a benchmark for quality in clinical practice, more cost-effective neurorehabilitation and improved outcomes for neurological patients undergoing rehabilitation.Aim: To conduct a systematic review, as part of the output of a European COST Action, to identify what recommendations are made for upper limb assessmen…

Nine new cases of hypnic headache

2011

Identification of three novel progranulin mutations in a series of patients affected by sporadic and familial frontotemporal lobar de generation. Pla…

2009

Facing the music : a critical enquiry into 'the dodo-bird verdict' to develop music psychotherapy theory

2015

‘The dodo-bird verdict’ represents a boggling outcome of research that shows no significant difference between the outcomes of a variety of psychotherapy treatments. Not being able to scientifically discriminate between psychotherapeutic treatments, casts doubt on their theoretical underpinnings, and even on their efficacy. This in turn presents professionals who use psychotherapeutic techniques - including music therapists - with a conundrum: What can explain this inability? And what can be done to solve the problem? Conceptual research methods were used to analyse literature in order to answer these questions. Various weaknesses were identified, both in theory construction and in research…