Search results for "Neurologi"

showing 10 items of 1189 documents

Hypoxanthine and purine compounds in plasma from patients with multiple sclerosis and psoriasis

2011

HypoxanthineSettore BIO/10 - BiochimicaPsoriasisMultiple sclerosiSettore MED/26 - NeurologiaHypoxanthine; Multiple sclerosis; Psoriasis
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Inclusive Design for Alzheimer’s Disease: Low-cost Treatments, Design and ICT

2019

Inability to acquire new memories, difficulty to remember recent events and to recognize objects, places and people, visual-spatial disorientation, these are some of the disorders with which who is affected by neurological diseases must learn to live with. In a continuously evolving society, where the decreasing birth rate and the drops in mortality are consistent, the job of Architecture is precisely to interpret the requirements and needs of people who have lost the canonical relationship with the world and give them the possibility to recover it or maintain it through communication channels that use their remaining ability to understand. The indoors and outdoors acquire a “prosthesis fun…

Incapacità di acquisire nuovi ricordi difficoltà nel ricordare eventi osservati recentemente mancata identificazione delle cose dei luoghi e delle persone disorientamento visivo-spaziale sono questi e molti altri i disturbi con cui devono imparare a convivere coloro che sono colpiti da malattie neurologiche. In una società in continua evoluzione dove la diminuzione della natalità e l’innalzamento della soglia di mortalità divengono costanti il compito dell’Architettura è proprio quello d’interpretare le esigenze e i bisogni di persone che hanno perso il rapporto canonico con il mondo e offrire loro le possibilità di recuperarlo o di mantenerlo attraverso canali di comunicazione che sfruttino le loro residue capacità di comprensione. Lo spazio interno ed esterno assume così una “funzione protesica” contenendo ed esprimendo in sé le conoscenze necessarie per la sua corretta fruizione riducendo il senso di frustrazione attraverso la sensazione di sicurezza e di benessere che il malato deve percepire vivendolo. Il presente saggio propone un contributo alla diffusione di conoscenze e di informazioni utili a coloro che operano nel settore della programmazione e della progettazione di strutture socio-sanitarie riportando soluzioni terapeutiche “non farmacologiche” low-cost e sostenibili promosse dalla ricerca tecnologica internazionale e nazionale nel settore della progettazione tecnologica e delle ICT e che hanno dimostrato di essere in grado di produrre significativi benefici sia ai malati sia ai caregivers.Settore ICAR/12 - Tecnologia Dell'Architettura
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Multi-subject fMRI analysis via combined independent component analysis and shift-invariant canonical polyadic decomposition

2014

Canonical polyadic decomposition (CPD) may face a local optimal problem when analyzing multi-subject fMRI data with inter-subject variability. Beckmann and Smith proposed a tensor PICA approach that incorporated an independence constraint to the spatial modality by combining CPD with ICA, and alleviated the problem of inter-subject spatial map (SM) variability.This study extends tensor PICA to incorporate additional inter-subject time course (TC) variability and to connect CPD and ICA in a new way. Assuming multiple subjects share common TCs but with different time delays, we accommodate subject-dependent TC delays into the CP model based on the idea of shift-invariant CP (SCP). We use ICA …

Independent component analysis (ICA)Speech recognitionModels NeurologicalMotor ActivityNeuropsychological TestsInter-subject variabilityta3112TimeMulti-subject fMRI dataFingersHumansCanonical polyadic decomposition (CPD)Computer SimulationMotor activityInvariant (mathematics)ta217ta113Brain MappingShift-invariant CP (SCP)General NeuroscienceBrainMagnetic Resonance ImagingIndependent component analysisAuditory PerceptionTensor PICASpatial mapsPsychologyAlgorithmJournal of Neuroscience Methods
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The Tachykinin Neuroimmune Connection in Inflammatory Pain

1991

Inflammationbusiness.industryCalcitonin Gene-Related PeptideGeneral NeuroscienceModels NeurologicalNeuropeptidesGenes fosPainSubstance PInflammatory painArthritis ExperimentalNervous SystemGeneral Biochemistry Genetics and Molecular BiologyRatsConnection (mathematics)History and Philosophy of ScienceTachykininsAnimalsHumansMedicineNervous System Physiological PhenomenaNeurons AfferentbusinessNeuroscienceAnnals of the New York Academy of Sciences
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Modelling the insect Mushroom Bodies: Application to sequence learning

2015

Learning and reproducing temporal sequences is a fundamental ability used by living beings to adapt behaviour repertoire to environmental constraints. This paper is focused on the description of a model based on spiking neurons, able to learn and autonomously generate a sequence of events. The neural architecture is inspired by the insect Mushroom Bodies (MBs) that are a crucial centre for multimodal sensory integration and behaviour modulation. The sequence learning capability coexists, within the insect brain computational model, with all the other features already addressed like attention, expectation, learning classification and others. This is a clear example that a unique neural struc…

InsectaComputer scienceCognitive NeuroscienceModels NeurologicalContext; Insect brain; Insect mushroom bodies; Learning; Neural model; Neuroscience; Spiking neurons; Algorithms; Animals; Attention; Computer Simulation; Insecta; Mushroom Bodies; Robotics; Serial Learning; Models NeurologicalContext (language use)Sensory systemSerial LearningInsect brain; Insect mushroom bodies; LearningArtificial IntelligenceLearningAnimalsAttentionComputer SimulationMushroom BodiesStructure (mathematical logic)Sequencebusiness.industryRoboticsInsect mushroom bodiesMushroom bodiesSequence learningArtificial intelligencebusinessInsect brainAlgorithmsNeural Networks
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Transcranial magnetic resonance imaging-guided focused ultrasound treatment at 1.5 T: a retrospective study on treatment and patient-related paramete…

2020

Objective: To present a retrospective analysis of patient- and sonication-related parameters of a group of patients treated with a transcranial magnetic resonance imaging (MRI)-guided focused ultrasound (tcMRgFUS) system integrated with a 1.5-T MRI unit. Methods: The data obtained from 59 patients, who underwent the tcMRgFUS procedure from January 2015 to April 2019, were retrospectively reviewed for this study. The following data, among others, were mainly collected: skull density ratio (SDR), skull area (SA), number of available transducer elements (Tx), and estimated focal power at target (FP). For each of the four different treatment stages, we calculated the number of sonication proces…

Interventional magnetic resonance imagingMaterials Science (miscellaneous)medicine.medical_treatmentParkinson's diseaseEssential TremorBiophysicsGeneral Physics and Astronomy01 natural sciencesFocused ultrasound0103 physical sciencesmedicinePlane orientationInterventional Magnetic Resonance ImagingPhysical and Theoretical Chemistry010306 general physicsMathematical Physicsmedicine.diagnostic_testbusiness.industryThalamotomySettore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaMagnetic resonance imagingRetrospective cohort studystereotaxic techniqueslcsh:QC1-999Settore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Parkinson Disease.essential tremor; high-intensity focused ultrasound ablation; interventional magnetic resonance imaging; Parkinson's disease; stereotaxic techniquesCoronal planeStereotaxic techniqueHigh-Intensity Focused Ultrasound AblationStereotaxic TechniqueSettore MED/26 - NeurologiaNuclear medicinebusinessSettore MED/36 - Diagnostica Per Immagini E Radioterapialcsh:Physics
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Diagnosis and therapeutic management of primary headache in an emergency setting

2013

Introduction and aim: Much headachers are under or mis-diagnoses and data regarding the proportion of patients attending an emergency department (ED) because of headache are still few. We conducted a retrospective observational study in an ED with the following aims: (a) estimate the proportion of headache attending to an ED (b) to estimate and describe the therapeutic management of primary headache and (c) to assessment the exam most frequently requested. Materials and methods: We collected data regarding patients diagnosed with headache consecutively attending the ED of the University of Palermo between September 2011 and March 2012. The study was approved by the ethics committee. Results: Between the semester evaluated 25110 subjects were admitted to ED headache suffers were equal to 1.6 %. Of these 263 (63.1 %) were woman and 154 (36.9 %). Mean age was 44.2 (DS ± 18.4) years (p = 0.068).According to ED registry headache admission was as follow assigned: 76.5 % with a diagnosis of headache 22.8 % with a secondary headache 0.7 % with Trigeminal Autonomic Cephalgias (TACs). Among those with a primary headache about 36 % of patient did not received a pharmacological treatment. Monotherapy was prescribed less frequently than combination therapy (19.1 vs 44.5 %).In monotherapy the most frequent medication were NSAIDs (28.3 %) benzodiazepines (26.7 %) and dopamine antagonists (11.7 %). Among those with a primary headache a CT scan was performed in the 124 subjects and 111 (34.8 %) had a neurologist consultation. Discussion: Our data are in line with the one previously reported in literature. The most frequently medication in the Italian ED were NSAIDs benzodiazepines dopamine antagonists and steroids. Neverless our data unlikely can be compared to other study give a snapshot. We believe that much more can be done to improve treatment of primary headache in ED.Settore MED/26 - Neurologia
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Frequency of John Cunningham virus (JCV) DNA and of antibodies against JCV in patients affected by multiple sclerosis and their relationship with nat…

2012

JCV virus Natalizumab Multiple SclerosisSettore MED/26 - Neurologia
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Repeated courses of granulocyte colony-stimulating factor in amyotrophic lateral sclerosis: clinical and biological results from a prospective multic…

2011

Granulocyte colony-stimulating factor (G-CSF) induces a transient mobilization of hematopoietic progenitor cells from bone marrow to peripheral blood. Our aim was to evaluate safety of repeated courses of G-CSF in patients with amyotrophic lateral sclerosis (ALS), assessing disease progression and changes in chemokine and cytokine levels in serum and cerebrospinal fluid (CSF). Twenty-four ALS patients entered an open-label, multicenter trial in which four courses of G-CSF and mannitol were administered at 3-month intervals. Levels of G-CSF were increased after treatment in the serum and CSF. Few and transitory adverse events were observed. No significant reduction of the mean monthly decrea…

Keywords:amyotrophic lateral sclerosiclinical trialhematopoietic stem cellSettore MED/26 - Neurologiagranulocyte colony-stimulating factorneuroinflammation
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LEPROSY: A CASE REPORT FROM SICILY, ITALY

2009

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LEPROSYSettore MED/26 - Neurologia
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