Search results for "Neuropilins"

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Presence of the Transmembrane Protein Neuropilin in Cytokine-induced Killer Cells

2020

Background/aim Cytokine-induced killer (CIK) cells are a heterogenous population of immune cells showing promising applications in immunotherapeutic cancer treatment. Neuropilin (NRP) proteins have been proven to play an important role in cancer development and prognosis. In this study, CIK cells were tested for expression of NRPs, transmembrane proteins playing a role in the proliferation and survival of cancer cells. Materials and methods CIK cells were analyzed at different time points via flow cytometry and quantitative real-time polymerase chain reaction for neuropilin expression. Results Phenotyping results showed CIK cells having developed properly, and low levels of NRP2 were detect…

Cancer ResearchImmunologyCellBiologyFlow cytometryCytokine-Induced Killer CellsImmune systemNeoplasmsNeuropilin 1medicineNeuropilinHumansNeuropilinsFlow cytometryNeuropilin.A549 cellmedicine.diagnostic_testCytokine-induced killer cellGeneral MedicinePrognosisNeuropilin-1Neuropilin-2Gene Expression Regulation NeoplasticBrain tumorCytokine-induced killer cellmedicine.anatomical_structureOncologyA549 CellsCancer cellCancer researchImmunotherapyLung cancerAnticancer Research
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