Search results for "Nonparametric"
showing 7 items of 427 documents
Early developmental alterations of low-Mg2+ -induced epileptiform activity in the intact corticohippocampal formation of the newborn mouse in vitro.
2005
Abstract The generation, propagation and pharmacological properties of low-Mg 2+ -induced epileptiform activity were examined in the intact corticohippocampal formation (CHF) of the newborn (P0–4) mouse in vitro. Multi-site field potential recordings in dentate gyrus (DG), CA3, CA1, entorhinal cortex (EC) and temporal cortex (TC) revealed in 0.2 mM Mg 2+ -containing ACSF a stable pattern of spontaneous epileptiform activity consisting of recurrent ictal-like events (ILEs) and interictal events (IEs). Although this activity could be consistently observed as early as P0, ILEs were smaller in amplitude, less frequent and showed a slower onset in P0–2 as compared to P3–4 animals. In all age gro…
Transcriptional profiles from patients with dystrophinopathies and limb girdle muscular dystrophies as determined by qRT-PCR.
2003
Mutations in genes coding for the dystrophin-glycoprotein complex (DGC) cause inherited muscular dystrophies (MD), including Morbus Duchenne (DMD) and M. Becker (BMB) as well as limb-girdle muscular dystrophies (LGMD). New insights into the pathophysiology of the dystrophic muscle, the identification of compensatory mechanisms and additional proteins interacting with dystrophin are essential for developing new treatments. In order to define molecular mechanisms induced by lack of dystrophin and the subsequent counter-regulatory transcriptional response of degenerating muscle fibres, we have investigated the mRNA expression of 19 functionally linked genes in biopsies of patients with MD by m…
Common functional component modelling
2005
Functional data analysis (FDA) has become a popular technique in applied statistics. In particular, this methodology has received considerable attention in recent studies in empirical finance. In this talk we discuss selected topics of functional principal components analysis that are motivated by financial data.
Mixed estimation technique in semi-parametric space-time point processes for earthquake description
2013
An estimation approach for the semi-parametric intensity function of a particular space-time point process is introduced. In particular we want to account for the estimation of parametric and nonparametric components simultaneously, applying a forward predictive likelihood to semi-parametric models. For each event, the probability of being a background event or one belonging to a seismic sequence is therefore estimated.
SNP and SML estimation of univariate and bivariate binary–choice models
2008
We discuss the semi-nonparametric approach of Gallant and Nychka (1987, Econometrica 55: 363–390), the semiparametric maximum likelihood approach of Klein and Spady (1993, Econometrica 61: 387–421), and a set of new Stata commands for semiparametric estimation of three binary-choice models. The first is a univariate model, while the second and the third are bivariate models without and with sample selection, respectively. The proposed estimators are root-n consistent and asymptotically normal for the model parameters of interest under weak assumptions on the distribution of the underlying error terms. Our Monte Carlo simulations suggest that the efficiency losses of the semi-nonparametric a…
Confocal laser scanning microscopy for the study of the morphological changes of the postextraction sites
2012
A better understanding of the remodeling process of postextraction sockets is essential in dental treatment planning. The aim of this study was to evaluate whether confocal laser scanning microscopy (CLSM) can be applied to imaging contour changes of postextraction sites, as well as to its quantification with image analysis of obtained three-dimensional images. This work describes a new application of the CLSM technique. The system used was the OLS3100-USS, LEXT model (Olympus((R))). CLSM was used for the surface analysis of the extraction site. The measurements taken with CLSM were: (1) mesio-distal distance, (2) alveolar ridge thickness, and (3) vestibular and lingual alveolar ridge heigh…
La mesure de l'efficacité scolaire par la méthode de l'enveloppe : test des filières alternatives de recrutement des enseignants dans le cadre du pro…
2009
Data envelopment and school effectiveness: contract teachers' efficiency compared to civil servants in the Education for all process) In the context of EFA process, countries, in general the most depressed LDC, both constrained by scarcity of funding and urgency for expanding school access have set up new tracks for teacher recruitment on annually renewable contracts. Those teachers are often not professionally trained in regards with traditional pedagogical curricula. They receive much lower salaries than regular civil service teachers. This has been a controversial policy, but there is very limited evidence on the effectiveness or failure of contract teachers in improving student learning…