Search results for "Normal"
showing 10 items of 2571 documents
The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation.
1999
Gonadal differentiation is dependent upon a molecular cascade responsible for ovarian or testicular development from the bipotential gonadal ridge. Genetic analysis has implicated a number of gene products essential for this process, which include Sry, WT1, SF-1, and DAX-1. We have sought to better define the role of WT1 in this process by identifying downstream targets of WT1 during normal gonadal development. We have noticed that in the developing murine gonadal ridge, wt1 expression precedes expression of Dax-1, a nuclear receptor gene. We document here that the spatial distribution profiles of both proteins in the developing gonad overlap. We also demonstrate that WT1 can activate the D…
Physiological activation of the IgH 3' enhancer in B lineage cells is not blocked by Pax-5.
1996
The mouse 3' enhancer contains a high-affinity binding site for the paired box protein Pax-5. Here, we demonstrate by genomic footprinting that the rat 3' enhancer contains a low-affinity binding site for Pax-5, which is occupied in activated splenic B cells. Thus, binding of Pax-5 to the IgH 3' enhancer appears to be evolutionarily conserved in rodents. Analysis of Pax-5 expression in primary B cells demonstrates that Pax-5 remains expressed after 4 days of lipopolysaccharide (LPS) induction, but is down-regulated in 5-day stimulated cells. Similarly, the expression of Pax-5 is down-regulated in vivo in activated large splenocytes, in contrast to small resting cells. Multimerization of the…
A note on finite PST-groups
2007
[EN] A finite group G is said to be a PST-group if, for subgroups H and K of G with H Sylow-permutable in K and K Sylow-permutable in G, it is always the case that H is Sylow-permutable in G. A group G is a T*-group if, for subgroups H and K of G with H normal in K and K normal in G, it is always the case that H is Sylow-permutable in G. In this paper, we show that finite PST-groups and finite T*-groups are one and the same. A new characterisation of soluble PST-groups is also presented.
Algebraic (2, 2)-transformation groups
2009
This paper contains the more significant part of the article with the same title that will appear in the Volume 12 of Journal of Group Theory (2009). In this paper we determine all algebraic transformation groups $G$, defined over an algebraically closed field $\sf k$, which operate transitively, but not primitively, on a variety $\Omega$, provided the following conditions are fulfilled. We ask that the (non-effective) action of $G$ on the variety of blocks is sharply 2-transitive, as well as the action on a block $\Delta$ of the normalizer $G_\Delta$. Also we require sharp transitivity on pairs $(X,Y)$ of independent points of $\Omega$, i.e. points contained in different blocks.
Normal and Abnormal Tissue Classification in Positron Emission Tomography Oncological Studies
2018
Positron Emission Tomography (PET) imaging is increasingly used in radiotherapy environment as well as for staging and assessing treatment response. The ability to classify PET tissues, as normal versus abnormal tissues, is crucial for medical analysis and interpretation. For this reason, a system for classifying PET area is implemented and validated. The proposed classification is carried out using k-nearest neighbor (KNN) method with the stratified K-Fold Cross-Validation strategy to enhance the classifier reliability. A dataset of eighty oncological patients are collected for system training and validation. For every patient, lesion (abnormal tissue) and background (normal tissue around …
Laparoscopic management of an isolated left fallopian tube torsion due to twisted Morgagni hydatid in a pre-menarcheal girl.
2014
Isolated torsion of fallopian tube, meanwhile uncommon, should be considered in diagnosis of pelvic and lower abdominal pain. US investigation is an useful diagnostic tool. A prompt diagnosis could avoid salpingectomy and preserve fertility. Laparoscopy, as the first approach, should be preferred. We report a case of isolated tubal torsion occurring in a premenarcheal girl successfully managed by laparoscopy.
How relevant are local climate zones and urban climate zones for urban climate research? Dijon (France) as a case study.
2018
17 pages; International audience; Several typologies of urban surface properties have been proposed, in recent years, for urban heat island studies and climate modeling. Some were specifically developed for cities and urban climate issues, like the Urban Climate Zones, and the more recent Local Climate Zones. The initial objective of this paper is to evaluate the capacity of these two typologies to identify thermal environments in and around cities, and to determine which typology best captures the daily spatio-temporal patterns of surface and urban canopy heat islands. To simulate urban climate with a model, LULC data based on a given typology are required. To avoid circularity, we combine…
Por una muerte digna para la educación artística
2020
Resumen: El año 2020 ha estado marcado por una pandemia global causante de una situación extraña e impredecible a nivel planetario. Todos los países del mundo se encuentran en procesos de prevención sanitaria contra la COVID-19, un virus que ataca agresivamente el sistema inmunológico de las personas. Intentar llevar a cabo cualquier actividad supone un riesgo de contagio, ya que el coronavirus se propaga sobre todo a través del aliento humano, lo cual ha supuesto la irrupción de nuevos hábitos cotidianos, como usar siempre la mascarilla, o no poder reunirse con otra gente para celebraciones y eventos, ni tampoco dar clase en el aula. Inmersos en esta tesitura, desfavorable para cualquier i…
La música en Galdós II. La época de Fernando VII
2021
Las numerosas novelas históricas y las novelas normales de Galdós sitúan su acción entre 1804 y los comienzos del siglo XX. Este segundo estudio analiza los años entre 1814 a 1833, es decir, lo que ocurre respecto a la música en la época de Fernando VII. En ella encontraremos mucha música, pero también imágenes musicales como recurso comparativo.
Presència i ús del valencià en l'àmbit comercial
2021
El castellà i el valencià són les llengües oficials del País Valencià, però la seua presència i ús són desiguals. En aquesta superposició entre dues llengües, el castellà ocupa una posició hegemònica i el valencià una posició subordinada, la qual cosa provoca una diversificació de les seues funcions i dels seus àmbits d’ús, i l’adscripció de cada varietat (i dels seus parlants) a un estatus sociocultural específic. Els comportaments diglòssics i el bilingüisme de les persones valencianoparlants evidencien l’existència d’un conflicte lingüístic, que alhora és un conflicte sociopolític. Parlar de llengua al País Valencià és parlar de conflicte. L’objecte d’aquesta tesi és estudiar la presènci…