Search results for "Note"

Taopatch® combined with home-based training protocol to prevent sedentary lifestyle and biochemical changes in MS patients during COVID-19 pandemic

2021

In Multiple sclerosis (MS) it is important to preserve the residual physiological functions of subjects. The aim of the present study was to investigate the influence of nanotechnological device treatment combined with home-based training program (TP) on lactate level, hand grip strength and cervical mobility on MS patients. Seventeen MS patients were enrolled in the study and randomly assigned to an experimental group (EG) in which the Taopatch® nanotechnological device was applied or to a control group (CG). All the participants carried out a cervical range of motion (1) assessment and the hand grip test at baseline (T0) and after TP (T1), also investigating the lactate levels to figure o…

Targeted Therapies for Colorectal Cancer

2015

In the last decades, the standard chemotherapeutic approach for the metastatic colorectal cancer (mCRC) treatment was represented by a 5-FU-based regimen with the addition of either oxaliplatin or irinotecan. Recent discoveries in the molecular biology field led to the spread of so-called targeted agents whose mechanism of action is based on the binding with specific target molecules (cellular receptors or soluble proteins) responsible for the activation of many transduction pathways required for malignant cell growth and survival. Among these, the most important consist of monoclonal antibodies (mAbs) and the tyrosine kinase inhibitors (TKIs). As a consequence, the different mechanism of a…

Kriminālatbildība par ceļu satiksmes noteikumu un transportlīdzekļu ekspluatācijas noteikumu pārkāpšanu

2017

Ceļu satiksmes noteikumu un transportlīdzekļu ekspluatācijas noteikumu pārkāpšana ir aktuāls jautājums ne tikai administratīvajās tiesībās, bet arī krimināltiesībās. Noteikumu pārkāpšana apdraud sabiedriskās drošības intereses transportlīdzekļu kustības drošības un ekspluatācijas jomās. Bakalaura darba mērķis ir izpētīt ceļu satiksmes noteikumu un transportlīdzekļu ekspluatācijas noteikumu pārkāpšanas krimināltiesiskos aspektus, veicot noziedzīga nodarījuma analīzi un noteikumu pārkāpšanas krimināltiesisko regulējumu. Autore pētot Krimināllikuma 260.pantu pievēršas regulēšanas un piemērošanas problēmjautājumiem, un sniedz priekšlikumus. Rezultātā tiek uzsvērts, ka ceļu satiksmes noteikumu u…

Enhanced quantum sieving of hydrogen isotopes via molecular rearrangement of the adsorbed phase in chabazite

2020

Coadsorption experiments reveal an unexpected increase of the D2/H2 selectivity with loading in pure silica chabazite at 47 K. This effect is correlated with the appearance of a step in the adsorption isotherms of H2 and D2. Grand canonical Monte Carlo simulations show that this phenomenon is related to a molecular rearrangement of the adsorbed phase induced by its strong confinement. In the case of a H2 and D2 mixture, this rearrangement favors the adsorption of D2 having a smaller size due to quantum effects.

Efficient and rapid transformation of high silica CHA zeolite from FAU zeolite in the absence of water

2017

High silica CHA zeolite plays an important role in selective catalytic reduction of NOx with NH3 (NH3-SCR), but its synthesis is not highly efficient due to the use of a relatively high-cost structural directing agent (SDA) N,N,N-trimethyl-adamantammonium hydroxide (TMAdaOH) and relatively long crystallization time under hydrothermal conditions. Herein, we report an efficient and rapid synthesis of a high silica CHA zeolite possessing good crystallinity and uniform crystals (CHA-ST). The method includes interzeolite transformation of high silica FAU zeolite in the absence of water but the presence of zeolite seeds and a bromide form of the SDA. The absence of water in the synthesis signific…

Snapshots of the Formation of Inorganic MoS2 Onion-Type Fullerenes: A “Shrinking Giant Bubble” Pathway

2010

IF-ReS2 with Covalently Linked Porphyrin Antennae

2010

The preparation of inorganic and organic hybrid materials, of metals or semiconductor systems which are functionalized with functional molecules to fabricate devices — nanotechnology — is currently an area of intense activity in both fundamental science and applied science on an international scale. Principally, nanotechnology aims at manipulating atoms, molecules, and nanosize particles in a precise and controlled manner in order to build materials with a fundamentally new organization and novel properties. The embryonic stage of nanotechnology is atomic assembly, whereas the mature form of nanotechnology will be molecular assembly to make nano-building blocks for the design of nanocomposi…

A Novel Strategy to Study Electrostatic Effects in Chemical Reactions: Differences between the Role of Solvent and the Active Site of Chalcone Isomer…

2015

The electrostatic behavior of active site residues in enzyme catalysis is quite different from that of water molecules in solution. To highlight the electrostatic differences between both environments, we propose a QM/MM strategy to study the role of the environment in chemical reactions. The novelty of the present communication is that free energy surfaces are generated by means of two distinguished reaction coordinates: a solute coordinate and the electrostatic potential created by the environment. This is applied to analyze the origin of catalysis in the transformation of a chalcone into a flavanone, a Michael addition that requires the desolvation of the nucleophile.

Working Principles of Perovskite Solar Cells

2018

Role of hydrophobic forces in bilayer adhesion and fusion.

1992

With the aim of gaining more insight into the forces and molecular mechanisms associated with bilayer adhesion and fusion, the surface forces apparatus (SFA) was used for measuring the forces and deformations of interacting supported lipid bilayers. Concerning adhesion, we find that the adhesion between two bilayers can be progressively increased by up to two orders of magnitude if they are stressed to expose more hydrophobic groups. Concerning fusion, we find that the most important force leading to direct fusion is the hydrophobic attraction acting between the (exposed) hydrophobic interiors of bilayers; however, the occurrence of fusion is not simply related to the strength of the attrac…